The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing

CD13 Regulates Dendritic Cell Cross-Presentation and T Cell Responses by Inhibiting Receptor-Mediated Antigen Uptake

(2012) M. Ghosh et al.   JOURNAL OF IMMUNOLOGY

Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain

(2012) Bernard P. Roques et al.   NATURE REVIEWS DRUG DISCOVERY

Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment

(2012) L. Guzman-Rojas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1

(2011) Tina T Nguyen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Plasmodium falciparum Malaria M1 Alanyl Aminopeptidase (PfA-M1): Insights of Catalytic Mechanism and Function from MD Simulations

(2011) Peter M. Jones et al.   PLoS One

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

(2011) G. Kochan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1

(2011) Amit Gandhi et al.   Scientific Reports

A Leukotriene A4 Hydrolase-Related Aminopeptidase from Yeast Undergoes Induced Fit upon Inhibitor Binding

(2010) Charlotte Helgstrand et al.   JOURNAL OF MOLECULAR BIOLOGY

Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules

(2009) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Aminopeptidase Fingerprints, an Integrated Approach for Identification of Good Substrates and Optimal Inhibitors

(2009) Marcin Drag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for the inhibition of the essentialPlasmodium falciparumM1 neutral aminopeptidase

(2009) Sheena McGowan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiotensins in Alzheimer's disease – friend or foe?

(2009) Patrick G. Kehoe et al.   TRENDS IN NEUROSCIENCES

The neovasculature homing motif NGR: more than meets the eye

(2008) A. Corti et al.   BLOOD

Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase

(2008) Siew Chai et al.   BMC NEUROSCIENCE

Structure-Based Dissection of the Active Site Chemistry of Leukotriene A4 Hydrolase: Implications for M1 Aminopeptidases and Inhibitor Design

(2008) Fredrik Tholander et al.   CHEMISTRY & BIOLOGY

CD13 is a novel mediator of monocytic/endothelial cell adhesion

(2008) Paola Mina-Osorio et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The moonlighting enzyme CD13: old and new functions to target

(2008) Paola Mina-Osorio   TRENDS IN MOLECULAR MEDICINE