Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs

Design and synthesis of novel anti-tuberculosis agents from the celecoxib pharmacophore

(2015) Santosh B. Salunke et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Repurposing—a ray of hope in tackling extensively drug resistance in tuberculosis

(2015) Arundhati Maitra et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Virulence genes and cytokine profile in systemic murineCampylobacter coliinfection

(2015) Anja Klančnik et al.   Virulence

DNA Replication Is the Target for the Antibacterial Effects of Nonsteroidal Anti-Inflammatory Drugs

(2014) Zhou Yin et al.   CHEMISTRY & BIOLOGY

Medicinal properties of organotin compounds and their limitations caused by toxicity

(2014) Lin Niu et al.   INORGANICA CHIMICA ACTA

Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis

(2014) Stephen H. Gillespie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-inflammatory drugs interacting with Zn (II) metal ion based on thiocyanate and azide ligands: Synthesis, spectroscopic studies, DFT calculations and antibacterial assays

(2014) Hossein Chiniforoshan et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

TB Summit 2014

(2014) Arundhati Maitra et al.   Virulence

Efflux Inhibition with Verapamil Potentiates Bedaquiline in Mycobacterium tuberculosis

(2013) Shashank Gupta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inflammation in tuberculosis: interactions, imbalances and interventions

(2013) Stefan HE Kaufmann et al.   CURRENT OPINION IN IMMUNOLOGY

Low-Dose Aspirin and Ibuprofen's Sterilizing Effects on Mycobacterium tuberculosis Suggest Safe New Adjuvant Therapies for Tuberculosis

(2013) D. P. Eisen et al.   JOURNAL OF INFECTIOUS DISEASES

Ibuprofen Therapy Resulted in Significantly Decreased Tissue Bacillary Loads and Increased Survival in a New Murine Experimental Model of Active Tuberculosis

(2013) Cristina Vilaplana et al.   JOURNAL OF INFECTIOUS DISEASES

Nonsteroidal Antiinflammatory Drugs for Adjunctive Tuberculosis Treatment

(2013) Juraj Ivanyi et al.   JOURNAL OF INFECTIOUS DISEASES

Adjuvant Host-Directed Therapy with Types 3 and 5 but Not Type 4 Phosphodiesterase Inhibitors Shortens the Duration of Tuberculosis Treatment

(2013) Mamoudou Maiga et al.   JOURNAL OF INFECTIOUS DISEASES

Advances in the development of new tuberculosis drugs and treatment regimens

(2013) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor

(2013) A. Simonetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay

(2013) Juan D Guzman et al.   BMJ Open

Drug Repurposing: Far Beyond New Targets for Old Drugs

(2012) T. I. Oprea et al.   AAPS Journal

Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections

(2012) Leonard Amaral et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

An integrated surrogate model for screening of drugs against Mycobacterium tuberculosis

(2012) A. Gupta et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Is repositioning of drugs a viable alternative in the treatment of tuberculosis?

(2012) J. C. Palomino et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves

(2012) C. Brentnall et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials

(2012) B. Gold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis

(2011) Wen-Jun Gui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophages and control of granulomatous inflammation in tuberculosis

(2011) J L Flynn et al.   Mucosal Immunology

Efficacy and Safety of Ibuprofen and Acetaminophen in Children and Adults: A Meta-Analysis and Qualitative Review

(2010) Catherine A Pierce et al.   ANNALS OF PHARMACOTHERAPY

Inhibition of Bacterial Multidrug Resistance by Celecoxib, a Cyclooxygenase-2 Inhibitor

(2010) Arunasree M. Kalle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rip Van Winkle Wakes Up: Development of Tuberculosis Treatment in the 21st Century

(2010) William J. Burman   CLINICAL INFECTIOUS DISEASES

Drogas antituberculose: interações medicamentosas, efeitos adversos e utilização em situações especiais - parte 2: fármacos de segunda linha

(2010) Marcos Abdo Arbex et al.   Jornal Brasileiro de Pneumologia

Diffusion loading and drug delivery characteristics of alginate gel microparticles produced by a novel impinging aerosols method

(2010) Dewi M. Hariyadi et al.   JOURNAL OF DRUG TARGETING

Role of aspirin in tuberculous meningitis: A randomized open label placebo controlled trial

(2010) U.K. Misra et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Mycobacterium tuberculosis Drugome and Its Polypharmacological Implications

(2010) Sarah L. Kinnings et al.   PLoS Computational Biology

The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target

(2009) K. Mazumdar et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Organotin meclofenamic complexes: Synthesis, crystal structures and antiproliferative activity of the first complexes of meclofenamic acid – Novel anti-tuberculosis agents

(2009) Dimitra Kovala-Demertzi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Ibuprofen: pharmacology, efficacy and safety

(2009) K. D. Rainsford   INFLAMMOPHARMACOLOGY

Occupational carprofen photoallergic contact dermatitis

(2008) A.C. Kerr et al.   BRITISH JOURNAL OF DERMATOLOGY

The anti-inflammatory drug Diclofenac retains anti-listerial activityin vivo

(2008) N.K. Dutta et al.   LETTERS IN APPLIED MICROBIOLOGY

Determination of Molecular Properties Effectuating the Growth Inhibition of Mycobacterium Tuberculosis by Various Small Molecule Hydrazides

(2008) Ronald Bartzatt et al.   Letters in Drug Design & Discovery