Endothelial-mesenchymal transition harnesses HSP90α-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma

MNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer

(2019) Yue Cheng et al.   Cancer Management and Research

Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications

(2019) Yuxin Lin et al.   Journal of Hematology & Oncology

LncRNA MNX1-AS1 promotes glioblastoma progression through inhibition of miR-4443

(2018) Yan Gao et al.   ONCOLOGY RESEARCH

Cancer-associated fibroblasts induce antigen-specific deletion of CD8+ T Cells to protect tumour cells

(2018) Matthew A. Lakins et al.   Nature Communications

Myeloid-derived macrophages and secreted HSP90α induce pancreatic ductal adenocarcinoma development

(2018) Chia-Chi Chen et al.   OncoImmunology

Prognostic implications of tumor-infiltrating macrophages, M2 macrophages, regulatory T-cells, and indoleamine 2,3-dioxygenase-positive cells in primary diffuse large B-cell lymphoma of the central nervous system

(2018) Soo Jeong Nam et al.   OncoImmunology

Tumor-associated macrophages: from basic research to clinical application

(2017) Li Yang et al.   Journal of Hematology & Oncology

Osteopontin–integrin engagement induces HIF-1α–TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer

(2017) Chi-Shuan Fan et al.   Oncotarget

CD163-positive tumor-associated macrophages and CD8-positive cytotoxic lymphocytes are powerful diagnostic markers for the therapeutic stratification of osteosarcoma patients: An immunohistochemical analysis of the biopsies fromthe French OS2006 phase 3 trial

(2017) Anne Gomez-Brouchet et al.   OncoImmunology

Loss of Macrophage Low-Density Lipoprotein Receptor–Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-α InhibitionHighlights

(2016) Lin Zhu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression

(2016) M Zou et al.   ONCOGENE

The Endothelin-Integrin Axis Is Involved in Macrophage-induced Breast Cancer Cell Chemotactic Interactions with Endothelial Cells

(2014) Chia-Chi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1

(2013) Jia Lu et al.   CANCER CELL

Targeting the Tumor Microenvironment: From Understanding Pathways to Effective Clinical Trials

(2013) H. Fang et al.   CANCER RESEARCH

Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients

(2013) Mercedes Herrera et al.   CANCER SCIENCE

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders

(2011) Sonsoles Piera-Velazquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation

(2010) Patricia G. Yancey et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Secreted Heat Shock Protein 90α Induces Colorectal Cancer Cell Invasion through CD91/LRP-1 and NF-κB-mediated Integrin αVExpression

(2010) Jinn-Shiun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Desmoplasia of Pancreatic Ductal Adenocarcinoma

(2009) Stephen Pandol et al.   Clinical Gastroenterology and Hepatology

Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer

(2009) Hiroshi Kurahara et al.   JOURNAL OF SURGICAL RESEARCH

The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy

(2009) Xiaofeng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transforming Growth Factor   (TGF )-Stimulated Secretion of HSP90 : Using the Receptor LRP-1/CD91 To Promote Human Skin Cell Migration against a TGF -Rich Environment during Wound Healing

(2008) C.-F. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY