Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2

Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity

(2019) Bruno Sovran et al.   Scientific Reports

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases

(2019) Mathias L. Richard et al.   Nature Reviews Gastroenterology & Hepatology

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

(2019) José Luís Fachi et al.   Cell Reports

Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

(2019) Eunyoung Chun et al.   IMMUNITY

Vulnerability of the industrialized microbiota

(2019) Justin L. Sonnenburg et al.   SCIENCE

Inhibiting Growth of Clostridioides difficile by Restoring Valerate, Produced by the Intestinal Microbiota

(2018) Julie A.K. McDonald et al.   GASTROENTEROLOGY

Regulation of type 2 innate lymphoid cell–dependent airway hyperreactivity by butyrate

(2018) Christina Li-Ping Thio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

(2018) Rachel Fellows et al.   Nature Communications

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

You are what you eat: diet, health and the gut microbiota

(2018) Niv Zmora et al.   Nature Reviews Gastroenterology & Hepatology

Microbial metabolite sensor GPR43 controls severity of experimental GVHD

(2018) Hideaki Fujiwara et al.   Nature Communications

CXCL1 and CXCL2 Regulate NLRP3 Inflammasome Activation via G-Protein–Coupled Receptor CXCR2

(2017) Monoranjan Boro et al.   JOURNAL OF IMMUNOLOGY

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

(2016) Gerard E. Kaiko et al.   CELL

Dietary fiber and the short-chain fatty acid acetate promote resolution of neutrophilic inflammation in a model of gout in mice

(2016) Angélica T. Vieira et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection

(2015) Michael C. Abt et al.   Cell Host & Microbe

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

Interleukin-22 and CD160 play additive roles in the host mucosal response toClostridium difficileinfection in mice

(2015) Amir A. Sadighi Akha et al.   IMMUNOLOGY

Unique and redundant functions of NKp46+ILC3s in models of intestinal inflammation

(2015) Christina Song et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clostridium difficile infection and intestinal microbiota interactions

(2015) C. Rodriguez et al.   MICROBIAL PATHOGENESIS

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

(2015) Laurence Macia et al.   Nature Communications

Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance

(2015) Priscilla Johanesen et al.   Genes

Interleukin-22 Regulates the Complement System to Promote Resistance against Pathobionts after Pathogen-Induced Intestinal Damage

(2014) Mizuho Hasegawa et al.   IMMUNITY

Tryptophan Catabolism Restricts IFN-γ–Expressing Neutrophils andClostridium difficileImmunopathology

(2014) Mohamad El-Zaatari et al.   JOURNAL OF IMMUNOLOGY

An in vitro model of innate lymphoid cell function and differentiation

(2014) D SJ Allan et al.   Mucosal Immunology

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

(2014) Hao Xu et al.   NATURE

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

(2014) Casey M. Theriot et al.   Nature Communications

Role of Microbiota and Innate Immunity in RecurrentClostridium difficileInfection

(2014) Stefano Bibbò et al.   Journal of Immunology Research

The Central Role of the Gut Microbiota in Chronic Inflammatory Diseases

(2014) Caroline Marcantonio Ferreira et al.   Journal of Immunology Research

Faecal microbiota transplantation for the treatment of recurrent Clostridium difficile infection

(2013) Mark J. Koenigsknecht et al.   CURRENT OPINION IN GASTROENTEROLOGY

Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

(2013) Myung H. Kim et al.   GASTROENTEROLOGY

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adenosine A2A receptor activation reduces recurrence and mortality from Clostridium difficileinfection in mice following vancomycin treatment

(2012) Yuesheng Li et al.   BMC INFECTIOUS DISEASES

Critical Role for MyD88-Mediated Neutrophil Recruitment during Clostridium difficile Colitis

(2012) Irene Jarchum et al.   INFECTION AND IMMUNITY

Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression

(2012) Dallas R. Donohoe et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protective Role of Commensals against Clostridium difficile Infection via an IL-1 -Mediated Positive-Feedback Loop

(2012) M. Hasegawa et al.   JOURNAL OF IMMUNOLOGY

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

(2012) Samuel Huber et al.   NATURE

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

(2012) Trevor D. Lawley et al.   PLoS Pathogens

SCFAs Induce Mouse Neutrophil Chemotaxis through the GPR43 Receptor

(2011) Marco A. R. Vinolo et al.   PLoS One

Biology of Clostridium difficile: Implications for Epidemiology and Diagnosis

(2010) Carroll Karen C. et al.   Annual Review of Microbiology

Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

(2010) Jeffrey Ng et al.   GASTROENTEROLOGY

Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon

(2010) M. C. Rea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial diversity associated with the hydrothermal shrimpRimicaris exoculatagut and occurrence of a resident microbial community

(2009) Lucile Durand et al.   FEMS MICROBIOLOGY ECOLOGY

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

A Mouse Model of Clostridium difficile–Associated Disease

(2008) Xinhua Chen et al.   GASTROENTEROLOGY

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

(2008) Hiroaki Takatori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-22 in mucosal immunity

(2008) W Ouyang et al.   Mucosal Immunology

The role of microbiota in infectious disease

(2008) Bärbel Stecher et al.   TRENDS IN MICROBIOLOGY