Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

(2019) Gerard Minuesa et al.   Nature Communications

The PLGF/c-MYC/miR-19a axis promotes metastasis and stemness in gallbladder cancer

(2018) Huaifeng Li et al.   CANCER SCIENCE

MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial–mesenchymal transition

(2018) Feihu Hu et al.   OncoTargets and Therapy

The roles of ZEB1 in tumorigenic progression and epigenetic modifications

(2018) Yu Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Msi2 plays a carcinogenic role in esophageal squamous cell carcinoma via regulation of the Wnt/β-catenin and Hedgehog signaling pathways

(2017) Zhiwei Li et al.   EXPERIMENTAL CELL RESEARCH

Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer

(2017) Weiwei Sheng et al.   FASEB JOURNAL

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

(2017) Angela M. Krebs et al.   NATURE CELL BIOLOGY

Myc mediates cancer stem-like cells and EMT changes in triple negative breast cancers cells

(2017) Shuping Yin et al.   PLoS One

Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway

(2017) Weiwei Sheng et al.   Cell Death & Disease

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

(2017) Bogdan-Tiberius Preca et al.   Oncotarget

ERK signalling modulates epigenome to drive epithelial to mesenchymal transition

(2017) Mohit Navandar et al.   Oncotarget

ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC

(2017) Darina Lazarova et al.   Journal of Cancer

Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2

(2017) Melanie C. MacNicol et al.   Scientific Reports

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

(2016) Jill E. Larsen et al.   JOURNAL OF CLINICAL INVESTIGATION

Musashi-2 promotes migration and invasion in bladder cancer via activation of the JAK2/STAT3 pathway

(2016) Chenlu Yang et al.   LABORATORY INVESTIGATION

Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer

(2016) M-H Kang et al.   ONCOGENE

The ERK–ZEB1 pathway mediates epithelial–mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids

(2016) L-Y Chiu et al.   ONCOGENE

Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis

(2016) Alexander E. Kudinov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein

(2016) Weiwei Sheng et al.   Oncotarget

Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin

(2015) Yixiang Han et al.   PLoS One

Gli1 promotes transforming growth factor-beta1– and epidermal growth factor–induced epithelial to mesenchymal transition in pancreatic cancer cells

(2015) Qingfeng Liu et al.   SURGERY

Transformation of the intestinal epithelium by the MSI2 RNA-binding protein

(2015) Shan Wang et al.   Nature Communications

Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer

(2015) Gab-Yong Bae et al.   Oncotarget

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

(2014) Sun-Mi Park et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition

(2013) Lu He et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MSI2 expression is decreased in grade II of gastric carcinoma

(2013) Modjtaba Emadi-Baygi et al.   PATHOLOGY RESEARCH AND PRACTICE

The SOX2-Interactome in Brain Cancer Cells Identifies the Requirement of MSI2 and USP9X for the Growth of Brain Tumor Cells

(2013) Jesse L. Cox et al.   PLoS One

An MAPK-dependent pathway induces epithelial-mesenchymal transition via Twist activation in human breast cancer cell lines

(2013) Neill Y. Li et al.   SURGERY

c-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-beta induced epithelial–mesenchymal transition and invasion in prostate cancer

(2012) Michael D. Amatangelo et al.   CARCINOGENESIS

MSI2 protein expression predicts unfavorable outcome in acute myeloid leukemia

(2011) R. J. Byers et al.   BLOOD

Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer

(2011) Hiroshi Kurahara et al.   JOURNAL OF SURGICAL ONCOLOGY

Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells

(2010) Kyoung Bin Cho et al.   CANCER LETTERS

Regulation of myeloid leukaemia by the cell-fate determinant Musashi

(2010) Takahiro Ito et al.   NATURE