The SOX2-Interactome in Brain Cancer Cells Identifies the Requirement of MSI2 and USP9X for the Growth of Brain Tumor Cells

Concise Review: The Sox2-Oct4 Connection: Critical Players in a Much Larger Interdependent Network Integrated at Multiple Levels

(2013) Angie Rizzino   STEM CELLS

Complexities of TGF-β Targeted Cancer Therapy

(2012) Erin C. Connolly et al.   International Journal of Biological Sciences

Determination of Protein Interactome of Transcription Factor Sox2 in Embryonic Stem Cells Engineered for Inducible Expression of Four Reprogramming Factors

(2012) Zhiguang Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel mutations target distinct subgroups of medulloblastoma

(2012) Giles Robinson et al.   NATURE

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

(2012) Pieter J A Eichhorn et al.   NATURE MEDICINE

RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI3 Kinase/Akt Signaling Pathways

(2012) Jun Muto et al.   PLoS One

Musashi2 Is Required for the Self-Renewal and Pluripotency of Embryonic Stem Cells

(2012) Erin L. Wuebben et al.   PLoS One

BAG3 Protein Is Overexpressed in Human Glioblastoma and Is a Potential Target for Therapy

(2011) Michelina Festa et al.   AMERICAN JOURNAL OF PATHOLOGY

Aggressive myeloid leukemia formation is directed by the Musashi 2/Numb pathway

(2011) Lori N. Griner et al.   CANCER BIOLOGY & THERAPY

VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells

(2011) Lymor Ringer et al.   CANCER BIOLOGY & THERAPY

Oct4 links multiple epigenetic pathways to the pluripotency network

(2011) Junjun Ding et al.   CELL RESEARCH

NUMB does not impair growth and differentiation status of experimental gliomas

(2011) Philipp Euskirchen et al.   EXPERIMENTAL CELL RESEARCH

Banf1 is required to maintain the self-renewal of both mouse and human embryonic stem cells

(2011) J. L. Cox et al.   JOURNAL OF CELL SCIENCE

Systems biology provides new insights into the molecular mechanisms that control the fate of embryonic stem cells

(2011) Sunil K. Mallanna et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Landscape of the SOX2 protein-protein interactome

(2011) Xuefeng Fang et al.   PROTEOMICS

Refinements to Label Free Proteome Quantitation: How to Deal with Peptides Shared by Multiple Proteins

(2010) Ying Zhang et al.   ANALYTICAL CHEMISTRY

Ubiquitin becomes ubiquitous in cancer

(2010) Dingding Shi et al.   CANCER BIOLOGY & THERAPY

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

(2010) Debbie L.C. van den Berg et al.   Cell Stem Cell

An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease

(2010) Mercedes Pardo et al.   Cell Stem Cell

USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly

(2010) Delphine Théard et al.   EMBO JOURNAL

Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

(2010) Yoon-Jae Cho et al.   JOURNAL OF CLINICAL ONCOLOGY

Regulation of myeloid leukaemia by the cell-fate determinant Musashi

(2010) Takahiro Ito et al.   NATURE

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

(2010) Michael G Kharas et al.   NATURE MEDICINE

Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas

(2010) R Sutter et al.   ONCOGENE

Sox2 Uses Multiple Domains to Associate with Proteins Present in Sox2-Protein Complexes

(2010) Jesse L. Cox et al.   PLoS One

Proteomic Analysis of Sox2-Associated Proteins During Early Stages of Mouse Embryonic Stem Cell Differentiation Identifies Sox21 as a Novel Regulator of Stem Cell Fate

(2010) Sunil K. Mallanna et al.   STEM CELLS

FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination

(2009) Sirio Dupont et al.   CELL

Genomic Analyses of Musashi1 Downstream Targets Show a Strong Association with Cancer-related Processes

(2009) Raquel de Sousa Abreu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal

(2009) M. Abdouh et al.   JOURNAL OF NEUROSCIENCE

Ubiquitin-like Sequence in ASK1 Plays Critical Roles in the Recognition and Stabilization by USP9X and Oxidative Stress-Induced Cell Death

(2009) Hiroaki Nagai et al.   MOLECULAR CELL

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

(2009) Martin Schwickart et al.   NATURE

Control of AMPK-related kinases by USP9X and atypical Lys29/Lys33-linked polyubiquitin chains

(2008) Abdallah K. Al-Hakim et al.   BIOCHEMICAL JOURNAL

Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro

(2008) Qiang Huang et al.   BMC CANCER

Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy

(2008) Patricia C Sanchez-Diaz et al.   BMC CANCER

Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast

(2008) X. Cheng et al.   DEVELOPMENT

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

(2008) Jiancong Liang et al.   NATURE CELL BIOLOGY

SOX2Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity

(2008) Rosaria Maria Rita Gangemi et al.   STEM CELLS

The Ubiquitin E3 Ligase MARCH7 is Differentially Regulated by the Deubiquitylating Enzymes USP7 and USP9X

(2008) James A. Nathan et al.   TRAFFIC