Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
出版年份 2016 全文链接
标题
Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
作者
关键词
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出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 173, Issue 23, Pages 3292-3306
出版商
Wiley
发表日期
2016-10-17
DOI
10.1111/bph.13616
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Glutamine transporters in mammalian cells and their functions in physiology and cancer
- (2016) Yangzom D. Bhutia et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The Concise Guide to PHARMACOLOGY 2015/16: Transporters
- (2015) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2015/16: Enzymes
- (2015) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Experimental design and analysis and their reporting: new guidance for publication in BJP
- (2015) Michael J Curtis et al. BRITISH JOURNAL OF PHARMACOLOGY
- Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP
- (2015) John C McGrath et al. BRITISH JOURNAL OF PHARMACOLOGY
- Amino Acid Transporters in Cancer and Their Relevance to "Glutamine Addiction": Novel Targets for the Design of a New Class of Anticancer Drugs
- (2015) Y. D. Bhutia et al. CANCER RESEARCH
- The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
- (2015) Christopher Southan et al. NUCLEIC ACIDS RESEARCH
- Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal Adenocarcinoma
- (2015) Alan R. Penheiter et al. Biomed Research International
- The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy
- (2014) Yangzom D. Bhutia et al. Asian Journal of Pharmaceutical Sciences
- Physical Biology in Cancer. 4. Physical cues guide tumor cell adhesion and migration
- (2013) Kimberly M. Stroka et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target
- (2013) Luika A. Timmerman et al. CANCER CELL
- Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer
- (2013) G. Zhang et al. CLINICAL CANCER RESEARCH
- Imaging Tumour ATB0,+ Transport Activity by PET with the Cationic Amino Acid O-2((2-[18F]fluoroethyl)methyl-amino)ethyltyrosine
- (2013) Adrienne Müller et al. MOLECULAR IMAGING AND BIOLOGY
- Amino acid signalling upstream of mTOR
- (2013) Jenna L. Jewell et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Molecular Analysis of Precursor Lesions in Familial Pancreatic Cancer
- (2013) Tatjana Crnogorac-Jurcevic et al. PLoS One
- Nutrient signaling to mTOR and cell growth
- (2013) Jenna L. Jewell et al. TRENDS IN BIOCHEMICAL SCIENCES
- The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function
- (2012) Veena Coothankandaswamy et al. BIOCHEMICAL JOURNAL
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells
- (2012) Sayka Barry et al. CLINICAL & EXPERIMENTAL METASTASIS
- Integrative Survival-Based Molecular Profiling of Human Pancreatic Cancer
- (2012) Timothy R. Donahue et al. CLINICAL CANCER RESEARCH
- Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling
- (2012) D. A. Altomare et al. CURRENT MEDICINAL CHEMISTRY
- Differential Expression of Metabolic Genes in Tumor and Stromal Components of Primary and Metastatic Loci in Pancreatic Adenocarcinoma
- (2012) Nina V. Chaika et al. PLoS One
- Developments in metastatic pancreatic cancer: Is gemcitabine still the standard?
- (2012) Jie-Er Ying WORLD JOURNAL OF GASTROENTEROLOGY
- α-methyl-L-tryptophan: mechanisms for tracer localization of epileptogenic brain regions
- (2011) Diane C Chugani Biomarkers in Medicine
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- mTOR signaling in protein homeostasis
- (2011) Crystal S. Conn et al. CELL CYCLE
- Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
- (2011) Robbie Loewith et al. GENETICS
- SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer
- (2011) Senthil Karunakaran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Animal research: Reporting in vivo experiments: The ARRIVE guidelines
- (2010) Carol Kilkenny et al. BRITISH JOURNAL OF PHARMACOLOGY
- CXCL17 and ICAM2 Are Associated With a Potential Anti-Tumor Immune Response in Early Intraepithelial Stages of Human Pancreatic Carcinogenesis
- (2010) Nobuyoshi Hiraoka et al. GASTROENTEROLOGY
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt
- (2009) Huadong Pei et al. CANCER CELL
- Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
- (2009) Paul Nicklin et al. CELL
- Gemcitabine chemoresistance in pancreatic cancer: Molecular mechanisms and potential solutions
- (2009) Roland Andersson et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy
- (2008) Senthil Karunakaran et al. BIOCHEMICAL JOURNAL
- Therapeutic strategy targeting the mTOR-HIF-1α-VEGF pathway in ovarian clear cell adenocarcinoma
- (2008) Masaki Miyazawa et al. PATHOLOGY INTERNATIONAL
- Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond
- (2008) Vadivel Ganapathy et al. PHARMACOLOGY & THERAPEUTICS
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