Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection

Interplay of DDP4 and IP-10 as a Potential Mechanism for Cell Recruitment to Tuberculosis Lesions

(2018) Thomas Blauenfeldt et al.   Frontiers in Immunology

An Adjuvanted, Postfusion F Protein–Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults

(2017) Judith Falloon et al.   JOURNAL OF INFECTIOUS DISEASES

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

(2017) Ting Shi et al.   LANCET

In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity

(2016) Stephan Halle et al.   IMMUNITY

Structural and Nonstructural Viral Proteins Are Targets of T-Helper Immune Response against Human Respiratory Syncytial Virus

(2016) Elena Lorente et al.   MOLECULAR & CELLULAR PROTEOMICS

Altered Treg and cytokine responses in RSV-infected infants

(2016) Allison F. Christiaansen et al.   PEDIATRIC RESEARCH

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

(2016) Nicholas Collins et al.   Nature Communications

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection

(2016) Matheswaran Kandasamy et al.   PLoS Pathogens

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus

(2015) Maximillian S. Habibi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Enhanced Detection of Antigen-Specific CD4+T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers

(2015) Christopher J. Holland et al.   JOURNAL OF IMMUNOLOGY

Nonglycosylated G-Protein Vaccine Protects against Homologous and Heterologous Respiratory Syncytial Virus (RSV) Challenge, while Glycosylated G Enhances RSV Lung Pathology and Cytokine Levels

(2015) Sandra Fuentes et al.   JOURNAL OF VIROLOGY

Antiviral B cell and T cell immunity in the lungs

(2015) Christopher Chiu et al.   NATURE IMMUNOLOGY

The emerging role of resident memory T cells in protective immunity and inflammatory disease

(2015) Chang Ook Park et al.   NATURE MEDICINE

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

(2015) Agnieszka Jozwik et al.   Nature Communications

Airway Inflammation and Illness Severity in Response to Experimental Rhinovirus Infection in Asthma

(2014) Jie Zhu et al.   CHEST

Current concepts and progress in RSV vaccine development

(2014) Aleks K Guvenel et al.   Expert Review of Vaccines

CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection

(2014) Brian J. Laidlaw et al.   IMMUNITY

The CD4 T cell response to respiratory syncytial virus infection

(2014) Allison F. Christiaansen et al.   IMMUNOLOGIC RESEARCH

Prophylaxis with a Respiratory Syncytial Virus (RSV) Anti-G Protein Monoclonal Antibody Shifts the Adaptive Immune Response to RSV rA2-line19F Infection from Th2 to Th1 in BALB/c Mice

(2014) S. Boyoglu-Barnum et al.   JOURNAL OF VIROLOGY

The Increased Type-1 and Type-2 Chemokine Levels in Children with Acute RSV Infection Alter the Development of Adaptive Immune Responses

(2014) Valerija Vojvoda et al.   Biomed Research International

Lung dendritic cells imprint T cell lung homing and promote lung immunity through the chemokine receptor CCR4

(2013) Zamaneh Mikhak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lung-resident memory CD8 T cells (TRM ) are indispensable for optimal cross-protection against pulmonary virus infection

(2013) Tao Wu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lung niches for the generation and maintenance of tissue-resident memory T cells

(2013) D L Turner et al.   Mucosal Immunology

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

Protective and dysregulated T cell immunity in RSV infection

(2013) Peter J Openshaw et al.   Current Opinion in Virology

CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin

(2012) Akihiko Ichikawa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection

(2012) J Loebbermann et al.   Mucosal Immunology

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination

(2012) Xi Li et al.   VACCINE

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

A review of palivizumab and emerging therapies for respiratory syncytial virus

(2011) Kristin A Shadman et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes

(2011) Jason Greenbaum et al.   IMMUNOGENETICS

High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+T cell responses

(2011) Joseph J. Sabatino et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction of CXCR3- and CCR5-associated chemokines during acute hepatitis C virus infection

(2011) Marija Zeremski et al.   JOURNAL OF HEPATOLOGY

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

Respiratory Syncytial Virus Interferon Antagonist NS1 Protein Suppresses and Skews the Human T Lymphocyte Response

(2011) Shirin Munir et al.   PLoS Pathogens

Viral Load Drives Disease in Humans Experimentally Infected with Respiratory Syncytial Virus

(2010) John P. DeVincenzo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CD4+ T cells clear virus but augment disease in mice infected with respiratory syncytial virus. Comparison with the effects of CD8+ T cells

(2010) W. H. ALWAN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The HLA genomic loci map: expression, interaction, diversity and disease

(2009) Takashi Shiina et al.   JOURNAL OF HUMAN GENETICS

The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response

(2009) R. S. Akondy et al.   JOURNAL OF IMMUNOLOGY

Infection of HLA-DR1 Transgenic Mice with a Human Isolate of Influenza A Virus (H1N1) Primes a Diverse CD4 T-Cell Repertoire That Includes CD4 T Cells with Heterosubtypic Cross-Reactivity to Avian (H5N1) Influenza Virus

(2009) K. A. Richards et al.   JOURNAL OF VIROLOGY

CXCL10/CXCR3-mediated responses promote immunity to respiratory syncytial virus infection by augmenting dendritic cell and CD8+T cell efficacy

(2008) Dennis M. Lindell et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells

(2008) P. A. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA