Current concepts and progress in RSV vaccine development

Macronutrients during Pregnancy and Life-Threatening Respiratory Syncytial Virus Infections in Children

(2013) F. Martín Ferolla et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

High Morbidity and Mortality in Adults Hospitalized for Respiratory Syncytial Virus Infections

(2013) N. Lee et al.   CLINICAL INFECTIOUS DISEASES

Attenuation of Live Respiratory Syncytial Virus Vaccines Is Associated With Reductions in Levels of Nasal Cytokines

(2013) Ruth A. Karron et al.   JOURNAL OF INFECTIOUS DISEASES

Kinetics of the Neutralizing Antibody Response to Respiratory Syncytial Virus Infections in a Birth Cohort

(2013) C.J. Sande et al.   JOURNAL OF MEDICAL VIROLOGY

Regulatory T Cells Prevent Th2 Immune Responses and Pulmonary Eosinophilia during Respiratory Syncytial Virus Infection in Mice

(2013) L. R. Durant et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus G Protein CX3C Motif Impairs Human Airway Epithelial and Immune Cell Responses

(2013) T. Chirkova et al.   JOURNAL OF VIROLOGY

A Respiratory Syncytial Virus (RSV) Anti-G Protein F(ab')2 Monoclonal Antibody Suppresses Mucous Production and Breathing Effort in RSV rA2-line19F-Infected BALB/c Mice

(2013) S. Boyoglu-Barnum et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus and Recurrent Wheeze in Healthy Preterm Infants

(2013) Maarten O. Blanken et al.   NEW ENGLAND JOURNAL OF MEDICINE

Respiratory Syncytial Virus-Associated Hospitalizations Among Children Less Than 24 Months of Age

(2013) C. B. Hall et al.   PEDIATRICS

Safety and Immunogenicity of a Live Attenuated RSV Vaccine in Healthy RSV-Seronegative Children 5 to 24 Months of Age

(2013) Elissa Malkin et al.   PLoS One

Neonatal antibody responses are attenuated by interferon-  produced by NK and T cells during RSV infection

(2013) J. S. Tregoning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells

(2013) J. Loebbermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

Respiratory syncytial virus vaccine development

(2013) Larry J. Anderson   SEMINARS IN IMMUNOLOGY

Genetic stability of RSV-F expression and the restricted growth phenotype of a live attenuated PIV3 vectored RSV vaccine candidate (MEDI-534) following restrictive growth in human lung cells

(2013) Christine L. Nelson et al.   VACCINE

Bovine respiratory syncytial virus: infection dynamics within and between herds

(2013) T. B. Klem et al.   VETERINARY RECORD

Respiratory Syncytial Virus: Current Progress in Vaccine Development

(2013) Rajeev Rudraraju et al.   Viruses-Basel

Protective and dysregulated T cell immunity in RSV infection

(2013) Peter J Openshaw et al.   Current Opinion in Virology

Advances in and the potential of vaccines for respiratory syncytial virus

(2013) Patricia A Jorquera et al.   Expert Review of Respiratory Medicine

Adults 65 Years Old and Older Have Reduced Numbers of Functional Memory T Cells to Respiratory Syncytial Virus Fusion Protein

(2012) Anu Cherukuri et al.   Clinical and Vaccine Immunology

Increased Genetic and Phenotypic Stability of a Promising Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate by Reverse Genetics

(2012) C. Luongo et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

(2012) Gale Smith et al.   PLoS One

The role of non-viral antigens in the cotton rat model of respiratory syncytial virus vaccine-enhanced disease

(2012) Christine A. Shaw et al.   VACCINE

Safety and immunogenicity of a Sf9 insect cell-derived respiratory syncytial virus fusion protein nanoparticle vaccine

(2012) Gregory M. Glenn et al.   VACCINE

Nonclinical phenotypic and genotypic analyses of a Phase 1 pediatric respiratory syncytial virus vaccine candidate MEDI-559 (rA2cp248/404/1030ΔSH) at permissive and non-permissive temperatures

(2012) Jeanne H. Schickli et al.   VIRUS RESEARCH

A Critical Phenylalanine Residue in the Respiratory Syncytial Virus Fusion Protein Cytoplasmic Tail Mediates Assembly of Internal Viral Proteins into Viral Filaments and Particles

(2012) F. Y. Shaikh et al.   mBio

Animal models of human respiratory syncytial virus disease

(2011) Reinout A. Bem et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children

(2011) Harish Nair et al.   BMC PUBLIC HEALTH

Respiratory Syncytial Virus Binds and Undergoes Transcription in Neutrophils From the Blood and Airways of Infants With Severe Bronchiolitis

(2011) Clare P. Halfhide et al.   JOURNAL OF INFECTIOUS DISEASES

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

(2011) J. S. McLellan et al.   JOURNAL OF VIROLOGY

Phase 1 Study of the Safety and Immunogenicity of a Live, Attenuated Respiratory Syncytial Virus and Parainfluenza Virus Type 3 Vaccine in Seronegative Children

(2011) David I. Bernstein et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Progress in understanding and controlling respiratory syncytial virus: Still crazy after all these years

(2011) Peter L. Collins et al.   VIRUS RESEARCH

Viral Load Drives Disease in Humans Experimentally Infected with Respiratory Syncytial Virus

(2010) John P. DeVincenzo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

(2010) Barney S. Graham   IMMUNOLOGICAL REVIEWS

Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence

(2010) A. F. G. Antonis et al.   JOURNAL OF GENERAL VIROLOGY

Respiratory Syncytial Virus F and G Proteins Induce Interleukin 1α, CC, and CXC Chemokine Responses by Normal Human Bronchoepithelial Cells

(2010) Christine M. Oshansky et al.   JOURNAL OF INFECTIOUS DISEASES

Neutralization of Human Respiratory Syncytial Virus Infectivity by Antibodies and Low-Molecular-Weight Compounds Targeted against the Fusion Glycoprotein

(2010) M. Magro et al.   JOURNAL OF VIROLOGY

Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life

(2010) N. Sigurs et al.   THORAX

The cotton rat model of respiratory viral infections

(2009) Marina S. Boukhvalova et al.   BIOLOGICALS

Innate Cells and T Helper 2 Cell Immunity in Airway Inflammation

(2009) Nora A. Barrett et al.   IMMUNITY

Activation of Interferon Response Through Toll-Like Receptor 3 Impacts Viral Pathogenesis and Pulmonary Toll-Like Receptor Expression During Respiratory Syncytial Virus and Influenza Infections in the Cotton Rat Sigmodon hispidus Model

(2009) Marina S. Boukhvalova et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I

(2009) Z. Ling et al.   JOURNAL OF VIROLOGY

The Level and Duration of RSV-Specific Maternal IgG in Infants in Kilifi Kenya

(2009) Rachel Ochola et al.   PLoS One

A dose-ranging study of a subunit Respiratory Syncytial Virus subtype A vaccine with and without aluminum phosphate adjuvantation in adults ≥65 years of age

(2009) Joanne M. Langley et al.   VACCINE

Soluble G protein of respiratory syncytial virus inhibits Toll-like receptor 3/4-mediated IFN-beta induction

(2008) M. Shingai et al.   INTERNATIONAL IMMUNOLOGY

Young Infants Can Develop Protective Levels of Neutralizing Antibody after Infection with Respiratory Syncytial Virus

(2008) Joshua J. Shinoff et al.   JOURNAL OF INFECTIOUS DISEASES

The Secreted Form of Respiratory Syncytial Virus G Glycoprotein Helps the Virus Evade Antibody-Mediated Restriction of Replication by Acting as an Antigen Decoy and through Effects on Fc Receptor-Bearing Leukocytes

(2008) A. Bukreyev et al.   JOURNAL OF VIROLOGY

The Role of T Cells in the Enhancement of Respiratory Syncytial Virus Infection Severity during Adult Reinfection of Neonatally Sensitized Mice

(2008) J. S. Tregoning et al.   JOURNAL OF VIROLOGY

Effectiveness of Maternal Influenza Immunization in Mothers and Infants

(2008) K. Zaman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activation of the Granzyme Pathway in Children With Severe Respiratory Syncytial Virus Infection

(2008) Reinout A Bem et al.   PEDIATRIC RESEARCH

Efficient induction of mucosal and systemic immune responses by virus-like particles administered intranasally: implications for vaccine design

(2007) Juliana Bessa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY