Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection

Transplantation Survival Is Maintained by Granzyme B+ Regulatory Cells and Adaptive Regulatory T Cells

(2014) D. C. Gondek et al.   JOURNAL OF IMMUNOLOGY

Suppression of Murine Allergic Airway Disease by IL-2:Anti-IL-2 Monoclonal Antibody-Induced Regulatory T Cells

(2014) M. S. Wilson et al.   JOURNAL OF IMMUNOLOGY

Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice

(2011) Paul R. Hiebert et al.   EXPERIMENTAL GERONTOLOGY

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

(2011) Jerome Thiery et al.   NATURE IMMUNOLOGY

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

Selective depletion of Foxp3+ Treg during sensitization phase aggravates experimental allergic airway inflammation

(2010) Abdul Mannan Baru et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Foxp3+ T Cells Induce Perforin-Dependent Dendritic Cell Death in Tumor-Draining Lymph Nodes

(2010) Alexandre Boissonnas et al.   IMMUNITY

Foxp3+ CD4 Regulatory T Cells Limit Pulmonary Immunopathology by Modulating the CD8 T Cell Response during Respiratory Syncytial Virus Infection

(2010) R. B. Fulton et al.   JOURNAL OF IMMUNOLOGY

CD25+ Natural Regulatory T Cells Are Critical in Limiting Innate and Adaptive Immunity and Resolving Disease following Respiratory Syncytial Virus Infection

(2010) D. C. P. Lee et al.   JOURNAL OF VIROLOGY

Interleukin 18 Coexpression during Respiratory Syncytial Virus Infection Results in Enhanced Disease Mediated by Natural Killer Cells

(2010) J. A. Harker et al.   JOURNAL OF VIROLOGY

The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response

(2009) G. Zelinskyy et al.   BLOOD

Regulatory T Cells in Asthma

(2009) Clare M. Lloyd et al.   IMMUNITY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

(2009) Kylie E. Webster et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-Specific Abundance of Regulatory T Cells Correlates with CD8+ T Cell Dysfunction and Chronic Retrovirus Loads

(2009) L. Myers et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Promote Early Influx of CD8+ T Cells in the Lungs of Respiratory Syncytial Virus-Infected Mice and Diminish Immunodominance Disparities

(2009) T. J. Ruckwardt et al.   JOURNAL OF VIROLOGY

Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma

(2009) Wendy Anne Boivin et al.   LABORATORY INVESTIGATION

Alveolar Macrophages Are a Major Determinant of Early Responses to Viral Lung Infection but Do Not Influence Subsequent Disease Development

(2008) P. K. Pribul et al.   JOURNAL OF VIROLOGY

The Role of T Cells in the Enhancement of Respiratory Syncytial Virus Infection Severity during Adult Reinfection of Neonatally Sensitized Mice

(2008) J. S. Tregoning et al.   JOURNAL OF VIROLOGY

Activation of the Granzyme Pathway in Children With Severe Respiratory Syncytial Virus Infection

(2008) Reinout A Bem et al.   PEDIATRIC RESEARCH

Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells

(2008) J. M. Lund et al.   SCIENCE