The tyrosine kinase inhibitor dasatinib reduces lung inflammation and remodelling in experimental allergic asthma

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

(2015) Coen H. Wiegman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Patient-reported side effects, concerns and adherence to corticosteroid treatment for asthma, and comparison with physician estimates of side-effect prevalence: a UK-wide, cross-sectional study

(2015) Vanessa Cooper et al.   npj Primary Care Respiratory Medicine

Platelet-derived growth factor mediates interleukin-13-induced collagen I production in mouse airway fibroblasts

(2014) Jiamei Lu et al.   JOURNAL OF BIOSCIENCES

Mitochondrial Structural Changes and Dysfunction Are Associated with Experimental Allergic Asthma

(2014) U. Mabalirajan et al.   JOURNAL OF IMMUNOLOGY

Inhaled Corticosteroids in Lung Diseases

(2013) Hengameh H. Raissy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Combining dasatinib with dexamethasone long-term leads to maintenance of antiviral and antileukemia specific cytotoxic T cell responses in vitro

(2013) Thomas Nerreter et al.   EXPERIMENTAL HEMATOLOGY

New anti-inflammatory targets for chronic obstructive pulmonary disease

(2013) Peter J. Barnes   NATURE REVIEWS DRUG DISCOVERY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Bone marrow-derived mononuclear cells vs. mesenchymal stromal cells in experimental allergic asthma

(2013) Soraia C. Abreu et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Dasatinib inhibits proinflammatory functions of mature human neutrophils

(2012) K. Futosi et al.   BLOOD

Dasatinib inhibits leukaemic cell survival by decreasing PRH/Hhex phosphorylation resulting in increased repression of VEGF signalling genes

(2012) Peter Noy et al.   LEUKEMIA RESEARCH

What effect does asthma treatment have on airway remodeling? Current perspectives

(2011) Sheharyar R. Durrani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Severe asthma: Advances in current management and future therapy

(2011) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lidocaine-derivative JMF2-1 prevents ovalbumin-induced airway inflammation by regulating the function and survival of T cells

(2010) P. C. Olsen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Gene Expression Alterations in Immune System Pathways in the Thymus after Exposure to Immunosuppressive Chemicals

(2010) Rachel Frawley et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Genetics of allergic disease

(2010) John W. Holloway et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

(2010) Jean Bousquet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Combined pharmacogenetic effect of ADCY9 and ADRB2 gene polymorphisms on the bronchodilator response to inhaled combination therapy

(2010) S. H. Kim et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Effects of bone marrow-derived mononuclear cells on airway and lung parenchyma remodeling in a murine model of chronic allergic inflammation

(2010) Soraia C. Abreu et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Tyrosine kinase inhibitors for the treatment of fibrotic diseases such as systemic sclerosis: towards molecular targeted therapies

(2009) J H W Distler et al.   ANNALS OF THE RHEUMATIC DISEASES

The tyrosine kinase network regulating mast cell activation

(2009) Alasdair M. Gilfillan et al.   IMMUNOLOGICAL REVIEWS

Chronic inflammation and asthma

(2009) Jenna R. Murdoch et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Airway smooth muscle hyperplasia and hypertrophy correlate with glycogen synthase kinase-3β phosphorylation in a mouse model of asthma

(2008) J. Kelley Bentley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils

(2008) M. Kneidinger et al.   BLOOD

Dasatinib inhibits the proliferation and function of CD4+CD25+regulatory T cells

(2008) Fei Fei et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro

(2008) Stephen Blake et al.   CLINICAL IMMUNOLOGY

Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukemia antigens

(2008) Fei Fei et al.   EXPERIMENTAL HEMATOLOGY

Targeting TNF-α: A novel therapeutic approach for asthma

(2007) Christopher Brightling et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY