Genipin alleviates sepsis-induced liver injury by restoring autophagy

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Impaired Autophagy Induces Chronic Atrophic Pancreatitis in Mice via Sex- and Nutrition-Dependent Processes

(2015) Kalliope N. Diakopoulos et al.   GASTROENTEROLOGY

Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation

(2015) Xiaorong Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cleavage of IκBα by calpain induces myocardial NF-κB activation, TNF-α expression, and cardiac dysfunction in septic mice

(2014) Xiaoping Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sepsis-induced changes in amino acid transporters and leucine signaling via mTOR in skeletal muscle

(2014) Lacee J. Laufenberg et al.   AMINO ACIDS

Association of autophagy-related 16-like 1 (ATG16L1) gene polymorphism with sepsis severity in patients with sepsis and ventilator-associated pneumonia

(2014) A. Savva et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The Role of Autophagy during Group BStreptococcusInfection of Blood-Brain Barrier Endothelium

(2014) Andrew S. Cutting et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice

(2014) Bo Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Autophagy-Related IRGM Polymorphism Is Associated with Mortality of Patients with Severe Sepsis

(2014) Tomonori Kimura et al.   PLoS One

Calpain 1 induce lysosomal permeabilization by cleavage of lysosomal associated membrane protein 2

(2013) Gloria E. Villalpando Rodriguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protective Effects of Geniposide and Genipin against Hepatic Ischemia/Reperfusion Injury in Mice

(2013) Joonki Kim et al.   Biomolecules & Therapeutics

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Augmenting Autophagy to Treat Acute Kidney Injury during Endotoxemia in Mice

(2013) Gina M. Howell et al.   PLoS One

Autophagy Induced by Tumor Necrosis Factor α Mediates Intrinsic Apoptosis in Trophoblastic Cells

(2013) Hyun-Hwa Cha et al.   Reproductive Sciences

Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury

(2013) Yu-Ting Yen et al.   SURGERY

Enhanced Liver Autophagic Activity Improves Survival of Septic Mice Lacking Surfactant Proteins A and D

(2013) Zhe Tang et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Calpastatin Controls Polymicrobial Sepsis by Limiting Procoagulant Microparticle Release

(2012) Lara Zafrani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lc3 Over-Expression Improves Survival and Attenuates Lung Injury Through Increasing Autophagosomal Clearance in Septic Mice

(2012) Steven Lo et al.   ANNALS OF SURGERY

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

(2012) Ilaria Dando et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363

(2012) F. Lamoureux et al.   CLINICAL CANCER RESEARCH

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(2012) Tae-Hoon Kim et al.   MOLECULAR MEDICINE

Autophagy and the regulation of the immune response

(2012) Rut Valdor et al.   PHARMACOLOGICAL RESEARCH

Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

(2012) Peter Recknagel et al.   PLOS MEDICINE

Complete Induction of Autophagy Is Essential for Cardioprotection in Sepsis

(2011) Chi-Hsun Hsieh et al.   ANNALS OF SURGERY

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

(2011) Ian G. Ganley et al.   MOLECULAR CELL

Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

(2011) R Russo et al.   Cell Death & Disease

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genipin protects lipopolysaccharide-induced apoptotic liver damage in d-galactosamine-sensitized mice

(2010) Seok-Joo Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

Impaired Autolysosome Formation Correlates With Lamp-2 Depletion: Role of Apoptosis, Autophagy, and Necrosis in Pancreatitis

(2009) Franco Fortunato et al.   GASTROENTEROLOGY

Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study

(2009) Eizo Watanabe et al.   LABORATORY INVESTIGATION

Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes

(2008) Jae-Sung Kim et al.   HEPATOLOGY