SIRT3, PP2A and TTP protein stability in the presence of TNF‐α on vincristine‐induced apoptosis of leukaemia cells

Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton

(2018) Michel O. Steinmetz et al.   TRENDS IN CELL BIOLOGY

Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphoma

(2018) Fen Yang et al.   Frontiers in Pharmacology

Non-mitotic effect of albendazole triggers apoptosis of human leukemia cells via SIRT3/ROS/p38 MAPK/TTP axis-mediated TNF-α upregulation

(2018) Liang-Jun Wang et al.   BIOCHEMICAL PHARMACOLOGY

NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway

(2017) Karen Bernard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease

(2016) Aneesa Ansari et al.   AGING CELL

Microtubule destabilising agents: far more than just antimitotic anticancer drugs

(2016) Darcy Bates et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells

(2016) A. Kothari et al.   CANCER RESEARCH

Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia

(2016) Patrick D. Bhola et al.   JOURNAL OF CLINICAL INVESTIGATION

Interaction with Pyruvate Kinase M2 Destabilizes Tristetraprolin by Proteasome Degradation and Regulates Cell Proliferation in Breast Cancer

(2016) Liangqian Huang et al.   Scientific Reports

Redox control of protein degradation

(2015) Marta Pajares et al.   Redox Biology

Sirt3 attenuates hydrogen peroxide-induced oxidative stress through the preservation of mitochondrial function in HT22 cells

(2014) SHU-HUI DAI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Sirt3 Protects Cortical Neurons against Oxidative Stress via Regulating Mitochondrial Ca2+ and Mitochondrial Biogenesis

(2014) Shu-Hui Dai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting Microtubules by Natural Agents for Cancer Therapy

(2014) E. Mukhtar et al.   MOLECULAR CANCER THERAPEUTICS

NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents

(2014) W. T. Harkcom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidases

(2013) William M. Nauseef   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Multidrug resistance in chronic myeloid leukaemia: how much can we learn from MDR–CML cell lines?

(2013) Vivian M. Rumjanek et al.   BIOSCIENCE REPORTS

p38 MAPK/PP2Acα/TTP pathway on the connection of TNF-α and caspases activation on hydroquinone-induced apoptosis

(2013) Wen-Hsin Liu et al.   CARCINOGENESIS

The MID1 E3 Ligase Catalyzes the Polyubiquitination of Alpha4 (α4), a Regulatory Subunit of Protein Phosphatase 2A (PP2A)

(2013) Haijuan Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of protein phosphatase 2A stable latency

(2013) Li Jiang et al.   Nature Communications

SIRT3 Functions in the Nucleus in the Control of Stress-Related Gene Expression

(2012) T. Iwahara et al.   MOLECULAR AND CELLULAR BIOLOGY

Microtubule-targeted agents: When mitochondria become essential to chemotherapy

(2011) A. Rovini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

(2011) Yaohui Chen et al.   EMBO REPORTS

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

Arecoline-induced death of human leukemia K562 cells is associated with surface up-modulation of TNFR2

(2011) Ying-Jung Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitosis is not a key target of microtubule agents in patient tumors

(2011) Edina Komlodi-Pasztor et al.   Nature Reviews Clinical Oncology

Caffeine induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-fos pathway and activation of p38 MAPK/c-jun pathway

(2010) Wen-Hsin Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Microtubule-binding agents: a dynamic field of cancer therapeutics

(2010) Charles Dumontet et al.   NATURE REVIEWS DRUG DISCOVERY

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

(2010) J. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

α4 Is an Essential Regulator of PP2A Phosphatase Activity

(2009) Mei Kong et al.   MOLECULAR CELL