The MID1 E3 Ligase Catalyzes the Polyubiquitination of Alpha4 (α4), a Regulatory Subunit of Protein Phosphatase 2A (PP2A)

Mdm2 and MdmX partner to regulate p53

(2012) Xinjiang Wang et al.   FEBS LETTERS

Monoubiquitination Promotes Calpain Cleavage of the Protein Phosphatase 2A (PP2A) Regulatory Subunit α4, Altering PP2A Stability and Microtubule-associated Protein Phosphorylation

(2012) Guy R. Watkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TRIM16 Acts as an E3 Ubiquitin Ligase and Can Heterodimerize with Other TRIM Family Members

(2012) Jessica L. Bell et al.   PLoS One

The E3 Ubiquitin Ligase- and Protein Phosphatase 2A (PP2A)-binding Domains of the Alpha4 Protein Are Both Required for Alpha4 to Inhibit PP2A Degradation

(2011) Michele LeNoue-Newton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Phosphatase 2A (PP2A)-specific Ubiquitin Ligase MID1 Is a Sequence-dependent Regulator of Translation Efficiency Controlling 3-Phosphoinositide-dependent Protein Kinase-1 (PDPK-1)

(2011) Beatriz Aranda-Orgillés et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection and Characterization of the In Vitro E3 Ligase Activity of the Human MID1 Protein

(2011) Xiaofeng Han et al.   JOURNAL OF MOLECULAR BIOLOGY

α4 is highly expressed in carcinogen-transformed human cells and primary human cancers

(2011) L-P Chen et al.   ONCOGENE

Overexpression of immunoglobulin (CD79a) binding protein1 (IGBP-1) in small lung adenocarcinomas and its clinicopathological significance

(2011) Shingo Sakashita et al.   PATHOLOGY INTERNATIONAL

NMR Studies of the C-Terminus of alpha4 Reveal Possible Mechanism of Its Interaction with MID1 and Protein Phosphatase 2A

(2011) Haijuan Du et al.   PLoS One

Control of mTORC1 signaling by the Opitz syndrome protein MID1

(2011) E. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase

(2009) Koji Okamoto et al.   FEBS LETTERS

α4 Is an Essential Regulator of PP2A Phosphatase Activity

(2009) Mei Kong et al.   MOLECULAR CELL

Structure of the MID1 Tandem B-Boxes Reveals an Interaction Reminiscent of Intermolecular Ring Heterodimers†,‡

(2008) Hu Tao et al.   BIOCHEMISTRY

The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex

(2008) Beatriz Aranda-Orgillés et al.   HUMAN GENETICS

Active Transport of the Ubiquitin Ligase MID1 along the Microtubules Is Regulated by Protein Phosphatase 2A

(2008) Beatriz Aranda-Orgillés et al.   PLoS One