FGFRL1 affects chemoresistance of small‐cell lung cancer by modulating the PI3K/Akt pathway via ENO1

WW domain-binding protein 2 acts as an oncogene by modulating the activity of the glycolytic enzyme ENO1 in glioma

(2018) Shuai Chen et al.   Cell Death & Disease

FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling

(2018) Haiyan Tai et al.   Journal of Immunology Research

Impact of baseline characteristics on extensive-stage SCLC patients treated with etoposide/carboplatin: A secondary analysis of a phase III study

(2018) Omar Abdel-Rahman   Clinical Respiratory Journal

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(2018) Shirish M. Gadgeel   CURRENT TREATMENT OPTIONS IN ONCOLOGY

NGR‐hTNF and Doxorubicin as Second‐Line Treatment of Patients with Small Cell Lung Cancer

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Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway

(2018) Jingbo Dai et al.   Nature Communications

A novel lncRNA, TCONS_00006195, represses hepatocellular carcinoma progression by inhibiting enzymatic activity of ENO1

(2018) Songman Yu et al.   Cell Death & Disease

Alpha-enolase promotes gastric cancer cell proliferation and metastasis via regulating AKT signaling pathway

(2018) Liang Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Alpha-Enolase i ENO1 i a potential target in novel immunotherapies

(2017) Francesco Novelli   Frontiers in Bioscience-Landmark

Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancer

(2017) Xiaoling Qian et al.   Oncotarget

Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer

(2016) Liyan Jiang et al.   PLoS Genetics

Global cancer statistics, 2012

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Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway

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FBXW7 negatively regulates ENO1 expression and function in colorectal cancer

(2015) Panpan Zhan et al.   LABORATORY INVESTIGATION

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(2015) David M. Ornitz et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in glioma

(2014) Ye Song et al.   Molecular Cancer

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1

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Fibroblast Growth Factor Receptor Like-1 (FGFRL1) Interacts with SHP-1 Phosphatase at Insulin Secretory Granules and Induces Beta-cell ERK1/2 Protein Activation

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Expression analysis of fibroblast growth factor receptor-like 1 (FGFRL1) in esophageal squamous cell carcinoma

(2013) Yutaka Shimada et al.   Esophagus

Role of FGFRL1 and other FGF signaling proteins in early kidney development

(2012) Beat Trueb et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Comparison of the Gene Expression Profiles from Normal and Fgfrl1 Deficient Mouse Kidneys Reveals Downstream Targets of Fgfrl1 Signaling

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Interaction of the receptor FGFRL1 with the negative regulator Spred1

(2011) Lei Zhuang et al.   CELLULAR SIGNALLING

MicroRNA-210 Regulates Cancer Cell Proliferation through Targeting Fibroblast Growth Factor Receptor-like 1 (FGFRL1)

(2010) Soken Tsuchiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The FGFRL1 Receptor Is Shed from Cell Membranes, Binds Fibroblast Growth Factors (FGFs), and Antagonizes FGF Signaling inXenopusEmbryos

(2009) Florian Steinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the first FGFRL1 mutation identified in a craniosynostosis patient

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