Dl‐3n‐butylphthalide improves traumatic brain injury recovery via inhibiting autophagy‐induced blood‐brain barrier disruption and cell apoptosis

ERK1/2/mTOR/Stat3 pathway-mediated autophagy alleviates traumatic brain injury-induced acute lung injury

(2018) Xiupeng Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NaHS restores mitochondrial function and inhibits autophagy by activating the PI3K/Akt/mTOR signalling pathway to improve functional recovery after traumatic brain injury

(2018) Kebin Xu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mdivi-1 alleviates blood-brain barrier disruption and cell death in experimental traumatic brain injury by mitigating autophagy dysfunction and mitophagy activation

(2018) Qiong Wu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The role of autophagy in acute brain injury: A state of flux?

(2018) Michael S. Wolf et al.   NEUROBIOLOGY OF DISEASE

Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood–Brain Barrier Permeability During Early Reperfusion in Stroke

(2018) Shuai Zhang et al.   NEUROSCIENCE

Impaired autophagic flux is associated with the severity of trauma and the role of A2AR in brain cells after traumatic brain injury

(2018) Xu-Jia Zeng et al.   Cell Death & Disease

Protective Role of L-3-n-Butylphthalide in Cognitive Function and Dysthymic Disorders in Mouse With Chronic Epilepsy

(2018) Xiaowen Ye et al.   Frontiers in Pharmacology

Mitochondrial Division Inhibitor 1 Prevents Early-Stage Induction of Mitophagy and Accelerated Cell Death in a Rat Model of Moderate Controlled Cortical Impact Brain Injury

(2018) Fei Niu et al.   World Neurosurgery

Dl-3-n-butylphthalide prevents the disruption of blood-spinal cord barrier via inhibiting endoplasmic reticulum stress following spinal cord injury

(2017) Binbin Zheng et al.   International Journal of Biological Sciences

dl-3-n-Butylphthalide (NBP) Provides Neuroprotection in the Mice Models After Traumatic Brain Injury via Nrf2-ARE Signaling Pathway

(2017) Zhengwei Liu et al.   NEUROCHEMICAL RESEARCH

l-3-n-Butylphthalide Activates Akt/mTOR Signaling, Inhibits Neuronal Apoptosis and Autophagy and Improves Cognitive Impairment in Mice with Repeated Cerebral Ischemia–Reperfusion Injury

(2017) Jing Xu et al.   NEUROCHEMICAL RESEARCH

DL-3-n-butylphthalide induced neuroprotection, regenerative repair, functional recovery and psychological benefits following traumatic brain injury in mice

(2017) Yingying Zhao et al.   NEUROCHEMISTRY INTERNATIONAL

Dl-3-n-Butylphthalide Treatment Enhances Hemodynamics and Ameliorates Memory Deficits in Rats with Chronic Cerebral Hypoperfusion

(2017) Zhilin Xiong et al.   Frontiers in Aging Neuroscience

Rehabilitation Treatment and Progress of Traumatic Brain Injury Dysfunction

(2017) Baoqi Dang et al.   NEURAL PLASTICITY

Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury

(2016) Cuicui Xie et al.   Autophagy

Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis

(2016) Hongxing Ye et al.   BMC Neurology

Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury

(2016) Yulong Zhou et al.   International Journal of Biological Sciences

Autophagy inhibition upregulates CD4+ tumor infiltrating lymphocyte expression via miR-155 regulation and TRAIL activation

(2016) Paul Zarogoulidis et al.   Molecular Oncology

Live to die another way: modes of programmed cell death and the signals emanating from dying cells

(2015) Yaron Fuchs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice

(2015) Ke Ding et al.   NEUROCHEMISTRY INTERNATIONAL

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

The Blood–Brain Barrier as a Target in Traumatic Brain Injury Treatment

(2014) Serge C. Thal et al.   ARCHIVES OF MEDICAL RESEARCH

Autophagic neuron death in neonatal brain ischemia/hypoxia

(2014) Yasuo Uchiyama et al.   Autophagy

Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

(2014) Chinmoy Sarkar et al.   Autophagy

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

(2014) Pei Wang et al.   Autophagy

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Modulating autophagy affects neuroamyloidogenesis in an in vitro ischemic stroke model

(2014) T. Zhang et al.   NEUROSCIENCE

Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death

(2014) C-J Lin et al.   Cell Death & Disease

Regulation of Autophagy and Ubiquitinated Protein Accumulation by bFGF Promotes Functional Recovery and Neural Protection in a Rat Model of Spinal Cord Injury

(2013) Hong-Yu Zhang et al.   MOLECULAR NEUROBIOLOGY

Autophagy Reduces Neuronal Damage and Promotes Locomotor Recovery via Inhibition of Apoptosis After Spinal Cord Injury in Rats

(2013) Peifu Tang et al.   MOLECULAR NEUROBIOLOGY

Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

(2012) Xiucui Ma et al.   CIRCULATION

Blood–brain barrier permeability is positively correlated with cerebral microvascular perfusion in the early fluid percussion-injured brain of the rat

(2012) Yong Lin et al.   LABORATORY INVESTIGATION

Incidence of traumatic brain injury in New Zealand: a population-based study

(2012) Valery L Feigin et al.   LANCET NEUROLOGY

dl-3-n-Butylphthalide prevents neuronal cell death after focal cerebral ischemia in mice via the JNK pathway

(2010) Jimei Li et al.   BRAIN RESEARCH

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE