Protective Role of L-3-n-Butylphthalide in Cognitive Function and Dysthymic Disorders in Mouse With Chronic Epilepsy

Cognition and dementia in older patients with epilepsy

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Temporal lobe epilepsy-induced neurodegeneration and cognitive deficits: Implications for aging

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Enhanced susceptibility to stress and seizures in GAD65 deficient mice

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Les comorbidités psychiatriques dans l’épilepsie

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Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits

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Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

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ΔFosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer’s Disease

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L-3-n-butylphthalide Rescues Hippocampal Synaptic Failure and Attenuates Neuropathology in Aged APP/PS1 Mouse Model of Alzheimer's Disease

(2016) Yu Zhang et al.   CNS Neuroscience & Therapeutics

Interictal serum brain-derived neurotrophic factor level reflects white matter integrity, epilepsy severity, and cognitive dysfunction in chronic temporal lobe epilepsy

(2016) Nai-Ching Chen et al.   EPILEPSY & BEHAVIOR

Dl-3-n-butylphthalide-induced upregulation of antioxidant defense is involved in the enhancement of cross talk between CREB and Nrf2 in an Alzheimer's disease mouse model

(2016) Chun-Yan Wang et al.   NEUROBIOLOGY OF AGING

Prevalence and incidence of epilepsy

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Garcinol Upregulates GABAA and GAD65 Expression, Modulates BDNF-TrkB Pathway to Reduce Seizures in Pentylenetetrazole (PTZ)-Induced Epilepsy

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L-3-n-butylphthalide Promotes Neurogenesis and Neuroplasticity in Cerebral Ischemic Rats

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The GAD65 knock out mouse - a model for GABAergic processes in fear- and stress-induced psychopathology

(2015) Iris Müller et al.   GENES BRAIN AND BEHAVIOR

L-3-n-Butylphthalide attenuates neuroinflammatory responses by downregulating JNK activation and upregulating Heme oxygenase-1 in lipopolysaccharide-treated mice

(2015) Chun-Yang Zhao et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

GAD65 epitope mapping and search for novel autoantibodies in GAD-associated neurological disorders

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Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice

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Pilocarpine-induced epilepsy is associated with actin cytoskeleton reorganization in the mossy fiber-CA3 synapses

(2014) Yan-Feng Zhang et al.   EPILEPSY RESEARCH

MiR-219 Protects Against Seizure in the Kainic Acid Model of Epilepsy

(2014) Honghua Zheng et al.   MOLECULAR NEUROBIOLOGY

Life Extension Factor Klotho Enhances Cognition

(2014) Dena B. Dubal et al.   Cell Reports

Downregulated GABA and BDNF-TrkB Pathway in Chronic Cyclothiazide Seizure Model

(2014) Shuzhen Kong et al.   NEURAL PLASTICITY

L-3-n-butylphthalide protects rats' cardiomyocytes from ischaemia/reperfusion-induced apoptosis by affecting the mitochondrial apoptosis pathway

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Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

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Behavioral impairments in rats with chronic epilepsy suggest comorbidity between epilepsy and attention deficit/hyperactivity disorder

(2013) Eduardo Pineda et al.   EPILEPSY & BEHAVIOR

Role of BDNF epigenetics in activity-dependent neuronal plasticity

(2013) Nina N. Karpova   NEUROPHARMACOLOGY

Stiff Person Syndrome and Other Anti-GAD-Associated Neurologic Disorders

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Epilepsy and psychiatric comorbidity: A nationally representative population-based study

(2012) Dheeraj Rai et al.   EPILEPSIA

The somatic comorbidity of epilepsy: A weighty but often unrecognized burden

(2012) Athanasios Gaitatzis et al.   EPILEPSIA

Small-molecule Klotho enhancers as novel treatment of neurodegeneration

(2012) Carmela R Abraham et al.   Future Medicinal Chemistry

Uncovering the neurobehavioural comorbidities of epilepsy over the lifespan

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Post-Weaning to Pre-Pubertal (‘Juvenile’) Stress: A Model of Induced Predisposition to Stress-Related Disorders

(2012) O. Horovitz et al.   NEUROENDOCRINOLOGY

Overexpression of Reelin Prevents the Manifestation of Behavioral Phenotypes Related to Schizophrenia and Bipolar Disorder

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Hippocampal-Dependent Spatial Memory in the Water Maze is Preserved in an Experimental Model of Temporal Lobe Epilepsy in Rats

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L-3-n-Butylphthalide Improves Cognitive Impairment and Reduces Amyloid-  in a Transgenic Model of Alzheimer's Disease

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Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies

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