CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis

Insulin-responsive amino peptidase follows the Glut4 pathway but is dispensable for the formation and translocation of insulin-responsive vesicles

(2019) Xiang Pan et al.   MOLECULAR BIOLOGY OF THE CELL

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

(2019) Matteo Fumagalli et al.   eLife

Clathrin heavy chain 22 contributes to the control of neuropeptide degradation and secretion during neuronal development

(2018) Michael S. Nahorski et al.   Scientific Reports

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function

(2017) Philip N. Dannhauser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes

(2017) Xiang Pan et al.   MOLECULAR BIOLOGY OF THE CELL

Update on GLUT4 Vesicle Traffic: A Cornerstone of Insulin Action

(2017) Javier R. Jaldin-Fincati et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Sec16A is critical for both conventional and unconventional secretion of CFTR

(2017) He Piao et al.   Scientific Reports

SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes

(2016) Joanne Bruno et al.   JOURNAL OF CELL BIOLOGY

A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development

(2015) Michael S. Nahorski et al.   BRAIN

Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway

(2015) Sophie Trefely et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Legionella suppresses the host unfolded protein response via multiple mechanisms

(2015) Sean Treacy-Abarca et al.   Nature Communications

Dynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide

(2014) K. P. Foley et al.   Biology Open

The ER-Golgi intermediate compartment feeds the phagophore membrane

(2013) Liang Ge et al.   Autophagy

Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin

(2013) Guanrong Huang et al.   MOLECULAR BIOLOGY OF THE CELL

The CHC22 Clathrin-GLUT4 Transport Pathway Contributes to Skeletal Muscle Regeneration

(2013) Sachiko Hoshino et al.   PLoS One

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

(2013) Liang Ge et al.   eLife

Regulation of Glucose Transporter Translocation in Health and Diabetes

(2012) Jonathan S. Bogan   Annual Review of Biochemistry

Diversity of Clathrin Function: New Tricks for an Old Protein

(2012) Frances M. Brodsky   Annual Review of Cell and Developmental Biology

Synchronization of secretory protein traffic in populations of cells

(2012) Gaelle Boncompain et al.   NATURE METHODS

Regulation of glucose transport by insulin: traffic control of GLUT4

(2012) Dara Leto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Ubiquitin Regulatory X (UBX) Domain-containing Protein TUG Regulates the p97 ATPase and Resides at the Endoplasmic Reticulum-Golgi Intermediate Compartment

(2011) Charisse M. Orme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Glycosylation Is Critical for the Stability and Intracellular Trafficking of Glucose Transporter GLUT4

(2011) Yoshimi Haga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

The Sugar Is sIRVed: Sorting Glut4 and Its Fellow Travelers

(2011) Konstantin V. Kandror et al.   TRAFFIC

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step

(2010) Christopher Esk et al.   JOURNAL OF CELL BIOLOGY

Insulin-regulated Aminopeptidase Is a Key Regulator of GLUT4 Trafficking by Controlling the Sorting of GLUT4 from Endosomes to Specialized Insulin-regulated Vesicles

(2010) Ingrid Jordens et al.   MOLECULAR BIOLOGY OF THE CELL

Insulin-Regulated Trafficking of GLUT4 Requires Ubiquitination

(2010) Christopher A. Lamb et al.   TRAFFIC

Legionella pneumophila Promotes Functional Interactions between Plasma Membrane Syntaxins and Sec22b

(2010) Kohei Arasaki et al.   TRAFFIC

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

(2009) D. J. Fazakerley et al.   JOURNAL OF CELL SCIENCE

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis

(2009) F. E. Hood et al.   JOURNAL OF CELL SCIENCE

A Role for the CHC22 Clathrin Heavy-Chain Isoform in Human Glucose Metabolism

(2009) S. Vassilopoulos et al.   SCIENCE

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL

Self-assembly of Glut4 Storage Vesicles during Differentiation of 3T3-L1 Adipocytes

(2008) Jun Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanisms Controlling GLUT4 Intracellular Retention

(2008) Vincent Blot et al.   MOLECULAR BIOLOGY OF THE CELL

Clathrin-Dependent and Independent Endocytosis of Glucose Transporter 4 (GLUT4) in Myoblasts: Regulation by Mitochondrial Uncoupling

(2008) Costin N. Antonescu et al.   TRAFFIC