Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding

Breaking the chains: deubiquitylating enzyme specificity begets function

(2019) Michael J. Clague et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cezanne/OTUD7B is a cell cycle‐regulated deubiquitinase that antagonizes the degradation of APC/C substrates

(2018) Thomas Bonacci et al.   EMBO JOURNAL

The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway

(2017) Yanxi Ji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling

(2017) Bin Wang et al.   NATURE

Genetically encoding new bioreactivity

(2017) Lei Wang   New Biotechnology

Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors

(2017) Christopher Price et al.   Frontiers in Cellular and Infection Microbiology

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

(2016) Tycho E. T. Mevissen et al.   NATURE

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

CDD/SPARCLE: functional classification of proteins via subfamily domain architectures

(2016) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

(2016) Carsten C. Scholz et al.   PLOS BIOLOGY

Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction

(2016) Michelle Vincendeau et al.   Scientific Reports

Cezanne regulates E2F1-dependent HIF2  expression

(2015) S. Moniz et al.   JOURNAL OF CELL SCIENCE

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Layers of DUB regulation

(2015) Danny D. Sahtoe et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cezanne (OTUD7B) regulates HIF-1  homeostasis in a proteasome-independent manner

(2014) A. Bremm et al.   EMBO REPORTS

Solution Structure of the Ubiquitin-associated (UBA) Domain of Human Autophagy Receptor NBR1 and Its Interaction with Ubiquitin and Polyubiquitin

(2014) Erik Walinda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel

(2014) S. Karttunen et al.   JOURNAL OF CELL SCIENCE

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2)

(2013) K. Janke et al.   JOURNAL OF CELL SCIENCE

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

(2013) Hongbo Hu et al.   NATURE

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions

(2012) Koraljka Husnjak et al.   Annual Review of Biochemistry

A Universal Expression Tag for Structural and Functional Studies of Proteins

(2012) Vladimir V. Rogov et al.   CHEMBIOCHEM

A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family

(2011) Iraia García-Santisteban et al.   BIOCHEMICAL JOURNAL

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression

(2011) F Pareja et al.   ONCOGENE

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

(2010) Anja Bremm et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases

(2010) Christoph Loenarz et al.   TRENDS IN BIOCHEMICAL SCIENCES

FIH-Dependent Asparaginyl Hydroxylation of Ankyrin Repeat Domain-Containing Proteins

(2009) Matthew E. Cockman et al.   Annals of the New York Academy of Sciences

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

(2009) David Komander et al.   EMBO REPORTS

Avid interactions underlie the Lys63-linked polyubiquitin binding specificities observed for UBA domains

(2009) Joshua J Sims et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NF-κB Suppression by the Deubiquitinating Enzyme Cezanne

(2008) Karine Enesa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atypical Binding of the Swa2p UBA Domain to Ubiquitin

(2008) Edna Matta-Camacho et al.   JOURNAL OF MOLECULAR BIOLOGY

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential ubiquitin binding of the UBA domains from human c-Cbl and Cbl-b: NMR structural and biochemical insights

(2008) Zi-Ren Zhou et al.   PROTEIN SCIENCE