Staging Alzheimer’s Disease in the Brain and Retina of B6.APP/PS1 Mice by Transcriptional Profiling

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity

(2019) Kathryn Cimdins et al.   MOLECULAR NEUROBIOLOGY

The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer’s Disease: Critical Aspects to Unravel

(2019) Samuel Chiquita et al.   MOLECULAR NEUROBIOLOGY

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

Exercise prevents obesity-induced cognitive decline and white matter damage in mice

(2019) Leah C. Graham et al.   NEUROBIOLOGY OF AGING

Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer’s Disease Therapeutic Development

(2019) Nevado-Holgado et al.   Cells

Enhancing face validity of mouse models of Alzheimer’s disease with natural genetic variation

(2019) Kristen D. Onos et al.   PLoS Genetics

Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer's disease

(2019) Clarissa Ferolla Mendonça et al.   NEUROBIOLOGY OF DISEASE

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

(2019) Elizabeth Spangenberg et al.   Nature Communications

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

(2018) Mariet Allen et al.   Alzheimers & Dementia

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

(2018) Sara E. Nasrabady et al.   Acta Neuropathologica Communications

Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer’s disease mouse model 5xFAD

(2018) Antonio Boza-Serrano et al.   Scientific Reports

The role of neurovascular unit damage in the occurrence and development of Alzheimer’s disease

(2018) Xin Liu et al.   REVIEWS IN THE NEUROSCIENCES

Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies

(2018) Hasnaa A. Elfawy et al.   LIFE SCIENCES

Absence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects With Alzheimer Disease

(2017) Erik A. Williams et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer’s disease

(2017) Marius Chiasseu et al.   Molecular Neurodegeneration

ApoE4 Accelerates Early Seeding of Amyloid Pathology

(2017) Chia-Chen Liu et al.   NEURON

Obesity as a risk factor for Alzheimer's disease: weighing the evidence

(2017) S. Alford et al.   Obesity Reviews

Imaging retina to study dementia and stroke

(2017) Carol Yim-lui Cheung et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Toward more predictive genetic mouse models of Alzheimer's disease

(2016) Kristen D. Onos et al.   BRAIN RESEARCH BULLETIN

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

(2016) Leah C. Graham et al.   Scientific Reports

The Eye As a Biomarker for Alzheimer's Disease

(2016) Jeremiah K. H. Lim et al.   Frontiers in Neuroscience

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

(2015) Marie-Victoire Guillot-Sestier et al.   NEURON

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections

(2014) Rekin's Janky et al.   PLoS Computational Biology

In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques

(2014) Steffen Burgold et al.   Acta Neuropathologica Communications

Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease

(2013) Harriet M Jackson et al.   BMC GENOMICS

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease

(2013) Pete A. Williams et al.   NEUROBIOLOGY OF AGING

Loss of thioredoxin function in retinas of mice overexpressing amyloid β

(2012) Folami Lamoke et al.   FREE RADICAL BIOLOGY AND MEDICINE

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult

(2012) Shaefali P Rodgers et al.   Molecular Neurodegeneration

The retina as a window to the brain—from eye research to CNS disorders

(2012) Anat London et al.   Nature Reviews Neurology

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE