MicroRNAs in Vascular Eye Diseases

MicroRNA-145 regulates pathological retinal angiogenesis by suppression of TMOD3

(2019) Chi-Hsiu Liu et al.   Molecular Therapy-Nucleic Acids

VEGF in Signaling and Disease: Beyond Discovery and Development

(2019) Rajendra S. Apte et al.   CELL

Retinal miRNA Functions in Health and Disease

(2019) Marta Zuzic et al.   Genes

Downregulation of miR-145-5p elevates retinal ganglion cell survival to delay diabetic retinopathy progress by targeting FGF5

(2019) Jingjing Zhang et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model

(2019) Michel Desjarlais et al.   PLoS One

Serum microRNA-21 predicted treatment outcome and survival in HER2-positive breast cancer patients receiving neoadjuvant chemotherapy combined with trastuzumab

(2019) Baoquan Liu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

MicroRNA‑31 is a potential biomarker for screening B‑lymphoblastic leukemia in children

(2019) Yan Zhang et al.   Oncology Letters

MicroRNA as a prognostic biomarker for survival in childhood acute lymphoblastic leukemia: a systematic review

(2019) Wafaa M. Rashed et al.   CANCER AND METASTASIS REVIEWS

Role of endothelial microRNA-23 clusters in angiogenesis in vivo

(2018) Satoshi Oikawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Upregulation of miR-221 and -222 in response to increased extracellular signal-regulated kinases 1/2 activity exacerbates neointimal hyperplasia in diabetes mellitus

(2018) Daniel J. Lightell et al.   ATHEROSCLEROSIS

Expression, regulation and function of miR-126 in the mouse choroid vasculature

(2018) Fangkun Zhao et al.   EXPERIMENTAL EYE RESEARCH

Molecular and functional characterization of circulating extracellular vesicles from diabetic patients with and without retinopathy and healthy subjects

(2018) Aurora Mazzeo et al.   EXPERIMENTAL EYE RESEARCH

MicroRNA-145 attenuates high glucose-induced oxidative stress and inflammation in retinal endothelial cells through regulating TLR4/NF-κB signaling

(2018) Ying Hui et al.   LIFE SCIENCES

MicroRNA-10b expression in breast cancer and its clinical association

(2018) Jianhui Zhang et al.   PLoS One

MicroRNA and Microvascular Complications of Diabetes

(2018) F. Barutta et al.   International Journal of Endocrinology

Circulating miRNAs as Predictive Biomarkers of Type 2 Diabetes Mellitus Development in Coronary Heart Disease Patients from the CORDIOPREV Study

(2018) Rosa Jiménez-Lucena et al.   Molecular Therapy-Nucleic Acids

MicroRNAs in Retinal Development

(2018) Thomas A. Reh et al.   Annual Review of Vision Science

Non-coding RNAs in retinal development and function

(2018) Marianthi Karali et al.   HUMAN GENETICS

MicroRNAs as biomarkers for clinical studies

(2017) Igor P Pogribny   EXPERIMENTAL BIOLOGY AND MEDICINE

Evaluation of the plasma microRNA levels in stage 3 premature retinopathy with plus disease: preliminary study

(2017) T Metin et al.   EYE

Animal models of ocular angiogenesis: from development to pathologies

(2017) Chi-Hsiu Liu et al.   FASEB JOURNAL

MicroRNA-200b Expression in the Vitreous Humor of Patients with Proliferative Diabetic Retinopathy

(2017) Amir Ramadan Gomaa et al.   OPHTHALMIC RESEARCH

MicroRNA-126 Reduces Blood-Retina Barrier Breakdown via the Regulation of VCAM-1 and BCL2L11 in Ischemic Retinopathy

(2017) Xia Bai et al.   OPHTHALMIC RESEARCH

miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes

(2017) Shali Chen et al.   PLoS One

MiR-211 is essential for adult cone photoreceptor maintenance and visual function

(2017) Sara Barbato et al.   Scientific Reports

Advances in Roles of miR-132 in the Nervous System

(2017) Yun Qian et al.   Frontiers in Pharmacology

Retinal and Circulating miRNAs in Age-Related Macular Degeneration: An In vivo Animal and Human Study

(2017) Giovanni L. Romano et al.   Frontiers in Pharmacology

Regulation of intraocular pressure by microRNA cluster miR-143/145

(2017) Xinyu Li et al.   Scientific Reports

MicroRNA-126 and micro-/macrovascular complications of type 1 diabetes in the EURODIAB Prospective Complications Study

(2016) Federica Barutta et al.   ACTA DIABETOLOGICA

Circulating microRNA-192 as a diagnostic biomarker in human chronic lymphocytic leukemia

(2016) S Fathullahzadeh et al.   CANCER GENE THERAPY

Identifying circulating microRNAs as biomarkers of cardiovascular disease: a systematic review

(2016) Rokas Navickas et al.   CARDIOVASCULAR RESEARCH

Role of MicroRNA 126 in screening, diagnosis, and prognosis of diabetic patients in Egypt

(2016) Noha A. Rezk et al.   IUBMB LIFE

miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFαto Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose

(2016) Eun-Ah Ye et al.   MEDIATORS OF INFLAMMATION

Clinical significance of microRNAs in chronic and acute human leukemia

(2016) Chien-Hung Yeh et al.   Molecular Cancer

Strand and Cell Type-specific Function of microRNA-126 in Angiogenesis

(2016) Qinbo Zhou et al.   MOLECULAR THERAPY

High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs

(2016) Marianthi Karali et al.   NUCLEIC ACIDS RESEARCH

The progress in understanding and treatment of diabetic retinopathy

(2016) Alan W. Stitt et al.   PROGRESS IN RETINAL AND EYE RESEARCH

MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD

(2016) Catherine Ménard et al.   Oncotarget

MicroRNA-126 contributes to Niaspan treatment induced vascular restoration after diabetic retinopathy

(2016) Yang Wang et al.   Scientific Reports

The microRNA expression profile of mouse Müller glia in vivo and in vitro

(2016) Stefanie G. Wohl et al.   Scientific Reports

The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b

(2016) Jia Li et al.   Molecular Therapy-Nucleic Acids

Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice

(2016) Liheng Shi et al.   PLoS One

Retinal expression of small non-coding RNAs in a murine model of proliferative retinopathy

(2016) Chi-Hsiu Liu et al.   Scientific Reports

Role of MicroRNA-150 and Glycoprotein Nonmetastatic Melanoma Protein B in Angiogenesis during Hyperoxia-Induced Neonatal Lung Injury

(2015) Telugu Narasaraju et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A panel of four decreased serum microRNAs as a novel biomarker for early Parkinson’s disease

(2015) Hui Dong et al.   BIOMARKERS

VEGF-Induced Expression of miR-17–92 Cluster in Endothelial Cells Is Mediated by ERK/ELK1 Activation and Regulates AngiogenesisNovelty and Significance

(2015) Aránzazu Chamorro-Jorganes et al.   CIRCULATION RESEARCH

Angiogenic MicroRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes

(2015) Anna Zampetaki et al.   DIABETES

A genetic variant regulating miR-126 is associated with sight threatening diabetic retinopathy

(2015) Annie K McAuley et al.   Diabetes & Vascular Disease Research

MicroRNA profiling unveils hyperglycaemic memory in the diabetic heart

(2015) Sarah Costantino et al.   EUROPEAN HEART JOURNAL

Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene TargetCCN1in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia

(2015) Lulu Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a

(2015) Sudheesh Pilakka-Kanthikeel et al.   Journal of Neuroinflammation

EndothelialmicroRNA-150is an intrinsic suppressor of pathologic ocular neovascularization

(2015) Chi-Hsiu Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling

(2015) Shira Landskroner-Eiger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development

(2015) N. Dimitrova et al.   Cancer Discovery

MicroRNA-27b, microRNA-101 and microRNA-128 inhibit angiogenesis by down-regulating vascular endothelial growth factor C expression in gastric cancers

(2015) Hai-Ting Liu et al.   Oncotarget

Histological Characterization of the Dicer1 Mutant Zebrafish Retina

(2015) Saeed Akhtar et al.   Journal of Ophthalmology

Serum MicroRNAs as Potential Biomarkers of AMD

(2015) Maciej Szemraj et al.   MEDICAL SCIENCE MONITOR

Serum MiRNA Biomarkers serve as a Fingerprint for Proliferative Diabetic Retinopathy

(2014) Shao Qing et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNAs in human lung cancer

(2014) Sung-Min Kang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hypoxia-Induced Deregulation of miR-126 and Its Regulative Effect on VEGF and MMP-9 Expression

(2014) Panpan Ye et al.   International Journal of Medical Sciences

Identification of Retinopathy of Prematurity Related miRNAs in Hyperoxia-Induced Neonatal Rats by Deep Sequencing

(2014) Ruibin Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

BDNF Promotes Axon Branching of Retinal Ganglion Cells via miRNA-132 and p250GAP

(2014) Katharine J. Marler et al.   JOURNAL OF NEUROSCIENCE

Lessons from miR-143/145: the importance of cell-type localization of miRNAs

(2014) Oliver A. Kent et al.   NUCLEIC ACIDS RESEARCH

A Circulating MicroRNA Profile Is Associated with Late-Stage Neovascular Age-Related Macular Degeneration

(2014) Felix Grassmann et al.   PLoS One

Up-Regulation of miRNA-146a in Progressive, Age-Related Inflammatory Neurodegenerative Disorders of the Human CNS

(2014) Peter N. Alexandrov et al.   Frontiers in Neurology

Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs

(2013) Loredana Fiorentino et al.   ACTA DIABETOLOGICA

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

Clinical Implication of MicroRNA for Lung Cancer

(2013) Yang Wang et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Current and Future Trends in Treatment of Severe Retinopathy of Prematurity

(2013) David K. Wallace et al.   CLINICS IN PERINATOLOGY

Microvesicle-mediated Transfer of MicroRNA-150 from Monocytes to Endothelial Cells Promotes Angiogenesis

(2013) Jing Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis

(2013) Zhen Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting

(2013) Peter D. Westenskow et al.   JOURNAL OF CLINICAL INVESTIGATION

Retinopathy of prematurity

(2013) Ann Hellström et al.   LANCET

Clinical evaluation of microRNA expression profiling in non small cell lung cancer

(2013) A. Markou et al.   LUNG CANCER

miRNA-27b Targets Vascular Endothelial Growth Factor C to Inhibit Tumor Progression and Angiogenesis in Colorectal Cancer

(2013) Jun Ye et al.   PLoS One

Dicer Expression Exhibits a Tissue-Specific Diurnal Pattern That Is Lost during Aging and in Diabetes

(2013) Yuanqing Yan et al.   PLoS One

Conserved microRNA pathway regulates developmental timing of retinal neurogenesis

(2013) A. La Torre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restricted perinatal retinal degeneration induces retina reshaping and correlated structural rearrangement of the retinotopic map

(2013) Nicola A. Maiorano et al.   Nature Communications

Role of miR-132 in Angiogenesis after Ocular Infection with Herpes Simplex Virus

(2012) Sachin Mulik et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNA-214 inhibits angiogenesis by targeting Quaking and reducing angiogenic growth factor release

(2012) Alain van Mil et al.   CARDIOVASCULAR RESEARCH

Microphthalmia-associated Transcription Factor (MITF) Promotes Differentiation of Human Retinal Pigment Epithelium (RPE) by Regulating microRNAs-204/211 Expression

(2012) Jeffrey Adijanto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms and Management of Retinopathy of Prematurity

(2012) M. Elizabeth Hartnett et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prevalence of Diabetic Retinopathy in Various Ethnic Groups: A Worldwide Perspective

(2012) Sobha Sivaprasad et al.   SURVEY OF OPHTHALMOLOGY

MicroRNAs in neuronal function and dysfunction

(2012) Heh-In Im et al.   TRENDS IN NEUROSCIENCES

Mutation Altering the miR-184 Seed Region Causes Familial Keratoconus with Cataract

(2011) Anne E. Hughes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

miRNeye: a microRNA expression atlas of the mouse eye

(2011) Marianthi Karali et al.   BMC GENOMICS

MicroRNA-24 Regulates Vascularity After Myocardial Infarction

(2011) Jan Fiedler et al.   CIRCULATION

MicroRNA-mediated regulation of the angiogenic switch

(2011) Sudarshan Anand et al.   CURRENT OPINION IN HEMATOLOGY

MicroRNA-200b Regulates Vascular Endothelial Growth Factor-Mediated Alterations in Diabetic Retinopathy

(2011) K. McArthur et al.   DIABETES

MicroRNA-126 inhibits ischemia-induced retinal neovascularization via regulating angiogenic growth factors

(2011) Yanyan Bai et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans

(2011) Loïc de Pontual et al.   NATURE GENETICS

miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

(2011) Rikako Sanuki et al.   NATURE NEUROSCIENCE

MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells

(2011) Céline Sabatel et al.   PLoS One

MicroRNA Expression and Clinical Outcome of Small Cell Lung Cancer

(2011) Jih-Hsiang Lee et al.   PLoS One

Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23 27 24 clusters

(2011) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EphA receptor signaling—Complexity and emerging themes

(2011) Hui Miao et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MicroRNAs and vascular (dys)function

(2011) Dorothee Hartmann et al.   VASCULAR PHARMACOLOGY

Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation

(2011) L. Du et al.   Journal of Molecular Cell Biology

Prediction of microRNAs affecting mRNA expression during retinal development

(2010) Amit Arora et al.   BMC DEVELOPMENTAL BIOLOGY

Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium

(2010) N. Davis et al.   DEVELOPMENT

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

(2010) Ryan M. O'Connell et al.   IMMUNITY

miR-200b Targets Ets-1 and Is Down-regulated by Hypoxia to Induce Angiogenic Response of Endothelial Cells

(2010) Yuk Cheung Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mediators of ocular angiogenesis

(2010) Yureeda Qazi et al.   JOURNAL OF GENETICS

Dicer Is Required for the Transition from Early to Late Progenitor State in the Developing Mouse Retina

(2010) S. A. Georgi et al.   JOURNAL OF NEUROSCIENCE

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

(2010) Sudarshan Anand et al.   NATURE MEDICINE

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Perturbations of MicroRNA Function in Mouse Dicer Mutants Produce Retinal Defects and Lead to Aberrant Axon Pathfinding at the Optic Chiasm

(2010) Rita Pinter et al.   PLoS One

miR-204 is required for lens and retinal development via Meis2 targeting

(2010) I. Conte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AngiomiRs—Key regulators of angiogenesis

(2009) Shusheng Wang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

(2009) M. Xin et al.   GENES & DEVELOPMENT

An Integrated Approach for Experimental Target Identification of Hypoxia-induced miR-210

(2009) Pasquale Fasanaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

(2009) Ángeles Mencía et al.   NATURE GENETICS

MicroRNAs couple cell fate and developmental timing in retina

(2009) Sarah Decembrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

The Pathogenesis of Age-related Macular Degeneration

(2008) Ephraim Friedman   AMERICAN JOURNAL OF OPHTHALMOLOGY

Endothelial EphA receptor stimulation increases lung vascular permeability

(2008) Jacqueline Larson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126

(2008) F. Kuhnert et al.   DEVELOPMENT

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3

(2008) Pasquale Fasanaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-21: a small multi-faceted RNA

(2008) Anna M. Krichevsky et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice

(2008) Motoyuki Otsuka et al.   JOURNAL OF CLINICAL INVESTIGATION

Dicer Inactivation Leads to Progressive Functional and Structural Degeneration of the Mouse Retina

(2008) D. Damiani et al.   JOURNAL OF NEUROSCIENCE

Age-related macular degeneration

(2008) Hanna R Coleman et al.   LANCET

MicroRNAs Regulate Ocular Neovascularization

(2008) JiKui Shen et al.   MOLECULAR THERAPY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Age-Related Macular Degeneration

(2008) Rama D. Jager et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis

(2008) Y. Suarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA