Up-Regulation of miRNA-146a in Progressive, Age-Related Inflammatory Neurodegenerative Disorders of the Human CNS

Age-Related Macular Degeneration (AMD): Alzheimer's Disease in the Eye?

(2018) Kai Kaarniranta et al.   JOURNAL OF ALZHEIMERS DISEASE

Retinal amyloid peptides and complement factor H in transgenic models of Alzheimerʼs disease

(2016) Peter N. Alexandrov et al.   NEUROREPORT

Immuno-miRs: critical regulators of T-cell development, function and ageing

(2014) Bart-Jan Kroesen et al.   IMMUNOLOGY

Prions and Prion-like Proteins

(2014) Paul E. Fraser   JOURNAL OF BIOLOGICAL CHEMISTRY

Phagocytosis of Microglia in the Central Nervous System Diseases

(2014) Ruying Fu et al.   MOLECULAR NEUROBIOLOGY

miRNAs and viroids utilize common strategies in genetic signal transfer

(2014) James M. Hill et al.   Frontiers in Molecular Neuroscience

Role of microRNA-146a in normal and malignant hematopoietic stem cell function

(2014) Jimmy L. Zhao et al.   Frontiers in Genetics

Identification of active transcription factor and miRNA regulatory pathways in Alzheimer’s disease

(2013) Wei Jiang et al.   BIOINFORMATICS

Regulation of Neurotropic Signaling by the Inducible, NF-kB-Sensitive miRNA-125b in Alzheimer's Disease (AD) and in Primary Human Neuronal-Glial (HNG) Cells

(2013) Yuhai Zhao et al.   MOLECULAR NEUROBIOLOGY

Circulating miRNA Biomarkers for Alzheimer's Disease

(2013) Pavan Kumar et al.   PLoS One

Identification of Unstable Network Modules Reveals Disease Modules Associated with the Progression of Alzheimer’s Disease

(2013) Masataka Kikuchi et al.   PLoS One

Variability in micro RNA (miRNA) abundance, speciation and complexity amongst different human populations and potential relevance to Alzheimer's disease (AD)

(2013) Walter J. Lukiw   Frontiers in Cellular Neuroscience

Studying micro RNA Function and Dysfunction in Alzheimer’s Disease

(2013) Walter J. Lukiw et al.   Frontiers in Genetics

Human Genetic Individuality

(2012) Maynard V. Olson   Annual Review of Genomics and Human Genetics

Regulation of Complement Factor H (CFH) by Multiple miRNAs in Alzheimer’s Disease (AD) Brain

(2012) Walter J. Lukiw et al.   MOLECULAR NEUROBIOLOGY

Spreading of Alzheimer’s disease inflammatory signaling through soluble micro-RNA

(2012) Walter J. Lukiw et al.   NEUROREPORT

MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State

(2012) Reuben Saba et al.   PLoS One

NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells

(2011) Walter J. Lukiw   EXPERIMENTAL NEUROLOGY

Upregulation of Micro RNA-146a (miRNA-146a), A Marker for Inflammatory Neurodegeneration, in Sporadic Creutzfeldt–Jakob Disease (sCJD) and Gerstmann–Straussler–Scheinker (GSS) Syndrome

(2011) W. J. Lukiw et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease

(2011) Stephen D. Ginsberg et al.   NEUROBIOLOGY OF DISEASE

miRNA-155 upregulation and complement factor H deficits in Down’s syndrome

(2011) Yuan Y. Li et al.   NEUROREPORT

Differential expression of miRNA-146a-regulated inflammatory genes in human primary neural, astroglial and microglial cells

(2011) Yuan Yuan Li et al.   NEUROSCIENCE LETTERS

Parallel findings in age-related macular degeneration and Alzheimer’s disease

(2011) Kyoko Ohno-Matsui   PROGRESS IN RETINAL AND EYE RESEARCH

Differential Regulation of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) and IRAK-2 by MicroRNA-146a and NF-κB in Stressed Human Astroglial Cells and in Alzheimer Disease

(2010) Jian Guo Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Export of microRNAs and microRNA-protective protein by mammalian cells

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

The Role of Complement Factor H in Age-related Macular Degeneration: A Review

(2010) Larry A. Donoso et al.   SURVEY OF OPHTHALMOLOGY

Gene Expression Variability within and between Human Populations and Implications toward Disease Susceptibility

(2010) Jingjing Li et al.   PLoS Computational Biology

Characterization of an NF-κB-regulated, miRNA-146a-mediated down-regulation of complement factor H (CFH) in metal-sulfate-stressed human brain cells

(2009) Aileen I. Pogue et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling

(2009) James M. Hill et al.   NEUROREPORT

Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex

(2009) Prerna Sethi et al.   NEUROSCIENCE LETTERS

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

(2008) Walter J. Lukiw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Native, amyloid fibrils and β-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly

(2008) Andreas P. Sjöberg et al.   MOLECULAR IMMUNOLOGY

A miRNA Signature of Prion Induced Neurodegeneration

(2008) Reuben Saba et al.   PLoS One