Micro RNA Molecules as Modulators of Treatment Resistance, Immune Checkpoints Controllers and Sensitive Biomarkers in Glioblastoma Multiforme

Implications of miRNA expression pattern in bovine oocytes and follicular fluids for developmental competence

(2020) R. Pasquariello et al.   THERIOGENOLOGY

Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2

(2019) Guo-zhong Yi et al.   BRAIN

PD-L1/PD-1 Axis in Glioblastoma Multiforme

(2019) Jakub Litak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression

(2018) Chunming Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

miR-204 reverses temozolomide resistance and inhibits cancer initiating cells phenotypes by degrading FAP-α in glioblastoma

(2018) Yun‑Na Yang et al.   Oncology Letters

Regulation of PD-L1: Emerging Routes for Targeting Tumor Immune Evasion

(2018) Yiting Wang et al.   Frontiers in Pharmacology

MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges

(2018) Alireza Mansouri et al.   NEURO-ONCOLOGY

Immune Checkpoints and Innovative Therapies in Glioblastoma

(2018) Massimo Romani et al.   Frontiers in Oncology

Epigenetic Targeting of Glioblastoma

(2018) Massimo Romani et al.   Frontiers in Oncology

Pseudoprogression, radionecrosis, inflammation or true tumor progression? challenges associated with glioblastoma response assessment in an evolving therapeutic landscape

(2017) Benjamin M. Ellingson et al.   JOURNAL OF NEURO-ONCOLOGY

Profiling bovine blastocyst microRNAs using deep sequencing

(2017) R. Pasquariello et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression

(2017) Wei Chen et al.   Oncotarget

The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma

(2017) Qi Ling et al.   Oncotarget

MicroRNA in Glioblastoma: An Overview

(2017) Barbara Banelli et al.   International Journal of Genomics

Circulating Tumor DNA as Biomarkers for Cancer Detection

(2017) Xiao Han et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer’s disease

(2017) Norikazu Hara et al.   Acta Neuropathologica Communications

Identification of IGF-1-enhanced cytokine expressions targeted by miR-181d in glioblastomas via an integrative miRNA/mRNA regulatory network analysis

(2017) Kuo-Hao Ho et al.   Scientific Reports

A restricted signature of serum miRNAs distinguishes glioblastoma from lower grade gliomas

(2016) Giulia Regazzo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Downregulation of serum microRNA-205 as a potential diagnostic and prognostic biomarker for human glioma

(2016) Xiao Yue et al.   JOURNAL OF NEUROSURGERY

Micro-RNA (miRNA) profile in Hodgkin lymphoma: association between clinical and pathological variables

(2016) Semra Paydas et al.   MEDICAL ONCOLOGY

miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint

(2016) Shaohua Xu et al.   Nature Communications

PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop

(2016) Yan Shi et al.   Oncotarget

The prognostic value of a seven-microRNA classifier as a novel biomarker for the prediction and detection of recurrence in glioma patients

(2016) Wanghao Chen et al.   Oncotarget

Prognostic relevance of miRNA-155 methylation in anaplastic glioma

(2016) Maximilian Georg Schliesser et al.   Oncotarget

MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma

(2016) Tian Tian et al.   Oncotarget

miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectly

(2016) Songhua Xiao et al.   Oncotarget

miR-28 modulates exhaustive differentiation of T cells through silencing programmed cell death-1 and regulating cytokine secretion

(2016) Qing Li et al.   Oncotarget

Potential Diagnostic and Prognostic Value of Plasma Circulating MicroRNA-182 in Human Glioma

(2016) Yilei Xiao et al.   MEDICAL SCIENCE MONITOR

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

(2016) Amanda Shea et al.   Cancer Medicine

Molecular and clinical characterization of PD-L1 expression at transcriptional level via 976 samples of brain glioma

(2016) Zheng Wang et al.   OncoImmunology

A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome

(2015) Bastian Fromm et al.   Annual Review of Genetics

Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells

(2015) Jessian L. Munoz et al.   CANCER LETTERS

Combination treatment with doxorubicin and microRNA-21 inhibitor synergistically augments anticancer activity through upregulation of tumor suppressing genes

(2015) SHANSHAN ZHANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

miR-873 acts as a novel sensitizer of glioma cells to cisplatin by targeting Bcl-2

(2015) XIONG CHEN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

miR-155 Regulates Glioma Cells Invasion and Chemosensitivity by p38 Isforms In Vitro

(2015) Qiang Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints

(2015) Jun Wei et al.   NEURO-ONCOLOGY

Decreased expression of microRNA-107 predicts poorer prognosis in glioma

(2015) Yuchen Ji et al.   TUMOR BIOLOGY

Stress Response of Glioblastoma Cells Mediated by miR-17-5p Targeting PTEN and the Passenger Strand miR-17-3p Targeting MDM2

(2015) Haoran Li et al.   Oncotarget

A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas

(2015) Deepa Kushwaha et al.   Oncotarget

MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma

(2015) Lin Wang et al.   Oncotarget

Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas

(2014) Yolande Berthois et al.   CANCER BIOLOGY & THERAPY

miR-221/222 Confers Radioresistance in Glioblastoma Cells Through Activating Akt Independent of PTEN Status

(2014) W. Li et al.   CURRENT MOLECULAR MEDICINE

MiR-136 modulates glioma cell sensitivity to temozolomide by targeting astrocyte elevated gene-1

(2014) Hao Wu et al.   Diagnostic Pathology

Effect of microRNA-21 on multidrug resistance reversal in A549/DDP human lung cancer cells

(2014) ZUOLIANG DONG et al.   Molecular Medicine Reports

MGMT testing—the challenges for biomarker-based glioma treatment

(2014) Wolfgang Wick et al.   Nature Reviews Neurology

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

(2014) Limo Chen et al.   Nature Communications

Understanding and Targeting Alkylator Resistance in Glioblastoma

(2014) W. Wick et al.   Cancer Discovery

microRNA-17 regulates the expression of ATG7 and modulates the autophagy process, improving the sensitivity to temozolomide and low-dose ionizing radiation treatments in human glioblastoma cells

(2013) Sergio Comincini et al.   CANCER BIOLOGY & THERAPY

Overexpressed miRNA-137 Inhibits Human Glioma Cells Growth by Targeting Rac1

(2013) Guan Sun et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma

(2013) Jun Wei et al.   CANCER RESEARCH

MiR-139 Inhibits Mcl-1 Expression and Potentiates TMZ-Induced Apoptosis in Glioma

(2013) Rui-Yan Li et al.   CNS Neuroscience & Therapeutics

Expressions of miRNAs in papillary thyroid carcinoma and their associations with the BRAFV600E mutation

(2013) Yongbo Huang et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Let-7b expression determines response to chemotherapy through the regulation of Cyclin D1 in Glioblastoma

(2013) Yong Guo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

miR-9 Regulation of BRCA1 and Ovarian Cancer Sensitivity to Cisplatin and PARP Inhibition

(2013) Chaoyang Sun et al.   JNCI-Journal of the National Cancer Institute

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients

(2013) Shuwei Qiu et al.   Journal of Translational Medicine

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis

(2013) Yun Zhang et al.   NATURE CELL BIOLOGY

MiR-145 functions as a tumor-suppressive RNA by targeting Sox9 and adducin 3 in human glioma cells

(2013) S. B. Rani et al.   NEURO-ONCOLOGY

MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma

(2012) Pedro M. Costa et al.   HUMAN MOLECULAR GENETICS

MiR-218 Impairs Tumor Growth and Increases Chemo-Sensitivity to Cisplatin in Cervical Cancer

(2012) Jiarui Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of glioma

(2012) Qiong Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Radiotherapy and concomitant temozolomide may improve survival of elderly patients with glioblastoma

(2012) Christopher A. Barker et al.   JOURNAL OF NEURO-ONCOLOGY

MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas

(2012) Simon Kjær Hermansen et al.   JOURNAL OF NEURO-ONCOLOGY

Tumor microRNA-335 expression is associated with poor prognosis in human glioma

(2012) Jian Jiang et al.   MEDICAL ONCOLOGY

A Systematic Review of MicroRNA in Glioblastoma Multiforme: Micro-modulators in the Mesenchymal Mode of Migration and Invasion

(2012) Heidi G. Møller et al.   MOLECULAR NEUROBIOLOGY

miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression

(2012) W. Zhang et al.   NEURO-ONCOLOGY

Correction: Monitoring of Regulatory T Cell Frequencies and Expression of CTLA-4 on T Cells, before and after DC Vaccination, Can Predict Survival in GBM Patients

(2012) Brendan Fong et al.   PLoS One

MiR-328 Expression Is Decreased in High-Grade Gliomas and Is Associated with Worse Survival in Primary Glioblastoma

(2012) Zhifeng Wu et al.   PLoS One

Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma

(2012) Jingchun Sun et al.   PLoS Computational Biology

Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function

(2011) I. Dunand-Sauthier et al.   BLOOD

2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size

(2011) David Capper et al.   INTERNATIONAL JOURNAL OF CANCER

MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status

(2011) Guang Yang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology

(2011) Byoung Kwon Yoo et al.   PHARMACOLOGY & THERAPEUTICS

A Ten-microRNA Expression Signature Predicts Survival in Glioblastoma

(2011) Sujaya Srinivasan et al.   PLoS One

miR-182 as a Prognostic Marker for Glioma Progression and Patient Survival

(2010) Lili Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

(2010) Zhang Chun-zhi et al.   BMC CANCER

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

(2010) Yu Ren et al.   BMC CANCER

MicroRNAs as biomarkers for CNS cancer and other disorders

(2010) Enrico De Smaele et al.   BRAIN RESEARCH

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma

(2010) Judit Anido et al.   CANCER CELL

miR-195, miR-455-3p and miR-10a∗ are implicated in acquired temozolomide resistance in glioblastoma multiforme cells

(2010) Kenta Ujifuku et al.   CANCER LETTERS

miR-31 Ablates Expression of the HIF Regulatory Factor FIH to Activate the HIF Pathway in Head and Neck Carcinoma

(2010) C.-J. Liu et al.   CANCER RESEARCH

Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations

(2010) Ce Liu et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Over-expression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J

(2010) Wooi Loon Ng et al.   DNA REPAIR

The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma

(2010) Feng Zhi et al.   EUROPEAN JOURNAL OF CANCER

Activation of AMP-activated Protein Kinase by Temozolomide Contributes to Apoptosis in Glioblastoma Cells via p53 Activation and mTORC1 Inhibition

(2010) Wen-bin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating miR-221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression

(2010) Xing-xiang Pu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

MicroRNA Expression Profiles Associated with Mutational Status and Survival in Malignant Melanoma

(2010) Stefano Caramuta et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Astrocyte Elevated Gene-1: A Novel Target for Human Glioma Therapy

(2010) L. Emdad et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients

(2010) O. Slaby et al.   NEOPLASMA

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas

(2009) Bastian Malzkorn et al.   BRAIN PATHOLOGY

microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs

(2009) Hongping Xia et al.   BRAIN RESEARCH

MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

(2009) Yiming Li et al.   BRAIN RESEARCH

MTDH Activation by 8q22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer

(2009) Guohong Hu et al.   CANCER CELL

MicroRNA Classifiers for Predicting Prognosis of Squamous Cell Lung Cancer

(2009) M. Raponi et al.   CANCER RESEARCH

Breast Cancer Metastasis Suppressor 1 Up-regulates miR-146, Which Suppresses Breast Cancer Metastasis

(2009) Douglas R. Hurst et al.   CANCER RESEARCH

RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis

(2009) Scott Valastyan et al.   CELL

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

(2009) J. T. Huse et al.   GENES & DEVELOPMENT

MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC

(2009) Takashi Sasayama et al.   INTERNATIONAL JOURNAL OF CANCER

Cryptosporidium parvumInduces B7‐H1 Expression in Cholangiocytes by Down‐Regulating MicroRNA‐513

(2009) Ai‐Yu Gong et al.   JOURNAL OF INFECTIOUS DISEASES

Emerging functions of microRNAs in glioblastoma

(2009) Sean Lawler et al.   JOURNAL OF NEURO-ONCOLOGY

miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors

(2009) Alfredo Conti et al.   JOURNAL OF NEURO-ONCOLOGY

MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets

(2009) Raffaele Baffa et al.   JOURNAL OF PATHOLOGY

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

(2008) Lei Shi et al.   BRAIN RESEARCH

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

(2008) B. Kefas et al.   CANCER RESEARCH

Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal

(2008) J. Godlewski et al.   CANCER RESEARCH

MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival

(2008) R. Medina et al.   CANCER RESEARCH

Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells

(2008) Shu Takakura et al.   CANCER SCIENCE

Deregulated expression of miR-106a predicts survival in human colon cancer patients

(2008) Raquel Díaz et al.   GENES CHROMOSOMES & CANCER

A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation

(2008) Zuoren Yu et al.   JOURNAL OF CELL BIOLOGY

MicroRNAs modulate the chemosensitivity of tumor cells

(2008) P. E. Blower et al.   MOLECULAR CANCER THERAPEUTICS

The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition

(2008) Nicole Cloonan et al.   GENOME BIOLOGY