MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma

P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK

(2012) Simiao Fan et al.   FREE RADICAL RESEARCH

Expression of miRNAs and PTEN in endometrial specimens ranging from histologically normal to hyperplasia and endometrial adenocarcinoma

(2012) Heejeong Lee et al.   MODERN PATHOLOGY

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

(2011) Ana L. Cardoso et al.   IMMUNOLOGY

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

(2011) A. B. Gaur et al.   NEURO-ONCOLOGY

Glioblastoma Models Reveal the Connection between Adult Glial Progenitors and the Proneural Phenotype

(2011) Liang Lei et al.   PLoS One

Specific miRNA signatures are associated with metastasis and poor prognosis in clear cell renal cell carcinoma

(2011) Joana Heinzelmann et al.   WORLD JOURNAL OF UROLOGY

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

(2010) Yu Ren et al.   BMC CANCER

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism

(2010) Prashanth Ak et al.   FASEB JOURNAL

Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3?

(2010) Sandro Alves et al.   HUMAN MOLECULAR GENETICS

Neuropeptide Y Modulation of Interleukin-1β (IL-1β)-induced Nitric Oxide Production in Microglia

(2010) Raquel Ferreira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-delivery of as-miR-21 and 5-FU by Poly(amidoamine) Dendrimer Attenuates Human Glioma Cell Growth in Vitro

(2010) Yu Ren et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides

(2010) Sara Trabulo et al.   JOURNAL OF CONTROLLED RELEASE

PI3Kinase signaling in glioblastoma

(2010) M. M. Lino et al.   JOURNAL OF NEURO-ONCOLOGY

Phase II study of sunitinib malate in patients with recurrent high-grade glioma

(2010) B. Neyns et al.   JOURNAL OF NEURO-ONCOLOGY

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Pifithrin-α, an Inhibitor of p53 Transactivation, Up-Regulates COX-2 Expression through an MAPK-Dependent Pathway

(2010) Sangmin Kim et al.   PHARMACOLOGY

Novel targeted agents for platelet-derived growth factor receptor and c-KIT in malignant gliomas

(2010) Patrick G. Morris et al.   Targeted Oncology

Advances in the Treatment of Malignant Gliomas

(2010) Mustafa Khasraw et al.   Current Oncology Reports

miR-21as a key regulator of oncogenic processes

(2009) S. Duygu Selcuklu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Emerging functions of microRNAs in glioblastoma

(2009) Sean Lawler et al.   JOURNAL OF NEURO-ONCOLOGY

miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors

(2009) Alfredo Conti et al.   JOURNAL OF NEURO-ONCOLOGY

Drugs targeting the mitochondrial pore act as citotoxic and cytostatic agents in temozolomide-resistant glioma cells

(2009) Annalisa Lena et al.   Journal of Translational Medicine

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

miRNA in situ hybridization in formaldehyde and EDC–fixed tissues

(2009) John T G Pena et al.   NATURE METHODS

The microRNA network and tumor metastasis

(2009) H Zhang et al.   ONCOGENE

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G

(2008) Yang Chen et al.   CANCER LETTERS

Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal

(2008) J. Godlewski et al.   CANCER RESEARCH

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

(2008) Shuomin Zhu et al.   CELL RESEARCH

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene

(2008) Z Lu et al.   ONCOGENE