Cancer Nano-Immunotherapy from the Injection to the Target: The Role of Protein Corona

Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2

(2019) Linh T. Nguyen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Serum type and concentration both affect the protein-corona composition of PLGA nanoparticles

(2019) Katrin Partikel et al.   Beilstein Journal of Nanotechnology

Biomaterial Surface Hydrophobicity-Mediated Serum Protein Adsorption and Immune Responses

(2019) Rahul M. Visalakshan et al.   ACS Applied Materials & Interfaces

Characterizing the protein corona of sub-10 nm nanoparticles

(2019) Dylan Glancy et al.   JOURNAL OF CONTROLLED RELEASE

Interaction of graphene oxide with cell culture medium: Evaluating the fetal bovine serum protein corona formation towards in vitro nanotoxicity assessment and nanobiointeractions

(2019) Lidiane S. Franqui et al.   Materials Science & Engineering C-Materials for Biological Applications

Precision Nanomedicine Development Based on Specific Opsonization of Human Cancer Patient-Personalized Protein Coronas

(2019) Jiayu Ren et al.   NANO LETTERS

Adaptation and memory in immune responses

(2019) Gioacchino Natoli et al.   NATURE IMMUNOLOGY

A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity

(2019) Kristina N Ekdahl et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Synthesis and Immunological Evaluation of Disaccharide Bearing MUC-1 Glycopeptide Conjugates with Virus-like Particles

(2019) Xuanjun Wu et al.   ACS Chemical Biology

Real‐world outcomes of sipuleucel‐T treatment in PROCEED, a prospective registry of men with metastatic castration‐resistant prostate cancer

(2019) Celestia S. Higano et al.   CANCER

Effect of nanoparticle size and PEGylation on the protein corona of PLGA nanoparticles

(2019) Katrin Partikel et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Experimental evolution of immunological specificity

(2019) Kevin Ferro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of Outer Membrane Vesicles as Cancer Vaccines: A New Toolkit for Cancer Therapy

(2019) Yingxuan Zhang et al.   Cancers

Nanotheranostics Targeting the Tumor Microenvironment

(2019) Catarina Roma-Rodrigues et al.   Frontiers in Bioengineering and Biotechnology

Fluorescence correlation spectroscopy as a tool for the study of the intracellular dynamics and biological fate of protein corona

(2019) Marta Martinez-Moro et al.   BIOPHYSICAL CHEMISTRY

Interplay of protein corona and immune cells controls blood residency of liposomes

(2019) Francesca Giulimondi et al.   Nature Communications

Cell Membrane Coating Nanotechnology

(2018) Ronnie H. Fang et al.   ADVANCED MATERIALS

Cell Membrane Bioconjugation and Membrane-Derived Nanomaterials for Immunotherapy

(2018) Peter Y. Li et al.   BIOCONJUGATE CHEMISTRY

Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue

(2018) Gilda Varricchi et al.   CURRENT MEDICINAL CHEMISTRY

Cancer vaccines: translation from mice to human clinical trials

(2018) Hoyoung Maeng et al.   CURRENT OPINION IN IMMUNOLOGY

Cell membrane coating for reducing nanoparticle-induced inflammatory responses to scaffold constructs

(2018) Zhiyuan Fan et al.   Nano Research

Engineering precision biomaterials for personalized medicine

(2018) Brian A. Aguado et al.   Science Translational Medicine

Current and Newly Emerging Autoimmune Diseases

(2018) Laurel J. Gershwin   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Human macrophage responses to metal-oxide nanoparticles: a review

(2018) Camila Figueiredo Borgognoni et al.   Artificial Cells Nanomedicine and Biotechnology

Safety and Efficacy of BIND-014, a Docetaxel Nanoparticle Targeting Prostate-Specific Membrane Antigen for Patients With Metastatic Castration-Resistant Prostate Cancer

(2018) Karen A. Autio et al.   JAMA Oncology

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Dense and Dynamic Polyethylene Glycol Shells Cloak Nanoparticles from Uptake by Liver Endothelial Cells for Long Blood Circulation

(2018) Hao Zhou et al.   ACS Nano

The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery

(2018) Matthias Bros et al.   Frontiers in Immunology

Altered Expression of CD300a Inhibitory Receptor on CD4+ T Cells From Human Immunodeficiency Virus-1-Infected Patients: Association With Disease Progression Markers

(2018) Joana Vitallé et al.   Frontiers in Immunology

Synthesis of Patient-Specific Nanomaterials

(2018) James Lazarovits et al.   NANO LETTERS

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

(2018) Qian Chen et al.   Nature Nanotechnology

Introduction to checkpoint inhibitors and cancer immunotherapy

(2017) Arlene H. Sharpe   IMMUNOLOGICAL REVIEWS

Correlation between early-life regulation of the immune system by microbiota and allergy development

(2017) Thomas Gensollen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ontak-like human IL-2 fusion toxin

(2017) Zhaohui Wang et al.   JOURNAL OF IMMUNOLOGICAL METHODS

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease

(2017) Mercy R. PrabhuDas et al.   JOURNAL OF IMMUNOLOGY

Macrophages as Key Drivers of Cancer Progression and Metastasis

(2017) Sebastian R. Nielsen et al.   MEDIATORS OF INFLAMMATION

Phase II study of paclitaxel associated with lipid core nanoparticles (LDE) as third-line treatment of patients with epithelial ovarian carcinoma

(2017) Silvia R. Graziani et al.   MEDICAL ONCOLOGY

Visualization of the protein corona: towards a biomolecular understanding of nanoparticle-cell-interactions

(2017) Maria Kokkinopoulou et al.   Nanoscale

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

(2017) Yuanzeng Min et al.   Nature Nanotechnology

Neoadjuvant Therapy with Weekly Nanoparticle Albumin‐Bound Paclitaxel for Luminal Early Breast Cancer Patients: Results from the NABRAX Study (GEICAM/2011‐02), a Multicenter, Non‐Randomized, Phase II Trial, with a Companion Biomarker Analysis

(2017) Miguel Martín et al.   ONCOLOGIST

Simplifying Logistics and Avoiding the Unnecessary in Patients With Breast Cancer Undergoing Sentinel Node Biopsy. A Prospective Feasibility Trial of the Preoperative Injection of Super Paramagnetic Iron Oxide Nanoparticles

(2017) A. Karakatsanis et al.   Scandinavian Journal of Surgery

Formation of the Protein Corona: The Interface between Nanoparticles and the Immune System

(2017) Francesco Barbero et al.   SEMINARS IN IMMUNOLOGY

Biocorona formation on gold nanoparticles modulates human proximal tubule kidney cell uptake, cytotoxicity and gene expression

(2017) M.T. Ortega et al.   TOXICOLOGY IN VITRO

In situ detection of the protein corona in complex environments

(2017) Monica Carril et al.   Nature Communications

Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics

(2017) Nicolas Bertrand et al.   Nature Communications

Personalized protein corona on nanoparticles and its clinical implications

(2017) Claudia Corbo et al.   Biomaterials Science

In Vitro and In Vivo Differences in Murine Third Complement Component (C3) Opsonization and Macrophage/Leukocyte Responses to Antibody-Functionalized Iron Oxide Nanoworms

(2017) Guankui Wang et al.   Frontiers in Immunology

Elucidation of the Physicochemical Properties Ruling the Colloidal Stability of Iron Oxide Nanoparticles under Physiological Conditions

(2017) Antonio Aires et al.   ChemNanoMat

The nanoparticle protein corona formed in human blood or human blood fractions

(2017) Martin Lundqvist et al.   PLoS One

Differential Protein Adsorption and Cellular Uptake of Silica Nanoparticles Based on Size and Porosity

(2016) Jiban Saikia et al.   ACS Applied Materials & Interfaces

Microdosed Lipid-Coated 67Ga-Magnetite Enhances Antigen-Specific Immunity by Image Tracked Delivery of Antigen and CpG to Lymph Nodes

(2016) Ane Ruiz-de-Angulo et al.   ACS Nano

A phase 2 study of nanoparticle albumin-bound paclitaxel plus nedaplatin for patients with advanced, recurrent, or metastatic cervical carcinoma

(2016) Yifan Li et al.   CANCER

Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors

(2016) D. D. Von Hoff et al.   CLINICAL CANCER RESEARCH

The influence of different long-circulating materials on the pharmacokinetics of liposomal vincristine sulfate

(2016) Xiang Li et al.   International Journal of Nanomedicine

Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors

(2016) Muhammad S. Beg et al.   INVESTIGATIONAL NEW DRUGS

Combinatorial approach to cancer immunotherapy: strength in numbers

(2016) Anna E. Vilgelm et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

(2016) Claudia Corbo et al.   Nanomedicine

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

(2016) Danny N. Khalil et al.   Nature Reviews Clinical Oncology

Protein corona acts as a protective shield against Fe 3 O 4 -PEG inflammation and ROS-induced toxicity in human macrophages

(2016) V. Escamilla-Rivera et al.   TOXICOLOGY LETTERS

The “Sweet” Side of the Protein Corona: Effects of Glycosylation on Nanoparticle–Cell Interactions

(2015) Sha Wan et al.   ACS Nano

Immune modulation of pathologic complete response after neoadjuvant HER2-directed therapies in the NeoSphere trial

(2015) G. Bianchini et al.   ANNALS OF ONCOLOGY

Synthetic Nanoparticles for Vaccines and Immunotherapy

(2015) Darrell J. Irvine et al.   CHEMICAL REVIEWS

Comparative examination of adsorption of serum proteins on HSA- and PLGA-based nanoparticles using SDS–PAGE and LC–MS

(2015) R. Gossmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Surface coating mediates the toxicity of polymeric nanoparticles towards human-like macrophages

(2015) Nadège Grabowski et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Diversity of Food Allergy

(2015) Tatsuya MORIYAMA   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Radiation and checkpoint blockade immunotherapy: radiosensitisation and potential mechanisms of synergy

(2015) Andrew B Sharabi et al.   LANCET ONCOLOGY

In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer

(2015) P. H. Lizotte et al.   Nature Nanotechnology

The fate of a designed protein corona on nanoparticles in vitro and in vivo

(2015) Denise Bargheer et al.   Beilstein Journal of Nanotechnology

T-cell-based Immunotherapy: Adoptive Cell Transfer and Checkpoint Inhibition

(2015) R. Houot et al.   Cancer Immunology Research

Classification of current anticancer immunotherapies

(2015) Lorenzo Galluzzi et al.   Oncotarget

Nanoparticle–Cell Interactions: Molecular Structure of the Protein Corona and Cellular Outcomes

(2014) Candace C. Fleischer et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cryptic Epitopes of Albumin Determine Mononuclear Phagocyte System Clearance of Nanomaterials

(2014) Gysell M. Mortimer et al.   ACS Nano

Monoclonal antibody conjugated magnetic nanoparticles could target MUC-1-positive cellsin vitrobut notin vivo

(2014) Saeed Shanehsazzadeh et al.   Contrast Media & Molecular Imaging

Secondary Structure of Corona Proteins Determines the Cell Surface Receptors Used by Nanoparticles

(2014) Candace C. Fleischer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

(2014) Sandra S. McAllister et al.   NATURE CELL BIOLOGY

Theranostics: An Iron Oxide Nanocarrier for dsRNA to Target Lymph Nodes and Strongly Activate Cells of the Immune System (Small 24/2014)

(2014) Macarena Cobaleda-Siles et al.   Small

Polymer-Coated Nanoparticles Interacting with Proteins and Cells: Focusing on the Sign of the Net Charge

(2013) Dominik Hühn et al.   ACS Nano

Immunopathogenic mechanisms of systemic autoimmune disease

(2013) Marie Wahren-Herlenius et al.   LANCET

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Nanomagnetic Sensing of Blood Plasma Protein Interactions with Iron Oxide Nanoparticles: Impact on Macrophage Uptake

(2012) Lénaic Lartigue et al.   ACS Nano

Reversible versus Irreversible Binding of Transferrin to Polystyrene Nanoparticles: Soft and Hard Corona

(2012) Silvia Milani et al.   ACS Nano

Alarmins: awaiting a clinical response

(2012) James K. Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Protection of Nonself Surfaces from Complement Attack by Factor H-Binding Peptides: Implications for Therapeutic Medicine

(2011) You-Qiang Wu et al.   JOURNAL OF IMMUNOLOGY

BSA Adsorption on Differently Charged Polystyrene Nanoparticles using Isothermal Titration Calorimetry and the Influence on Cellular Uptake

(2011) Grit Baier et al.   MACROMOLECULAR BIOSCIENCE

Cancer immunotherapy – revisited

(2011) W. Joost Lesterhuis et al.   NATURE REVIEWS DRUG DISCOVERY

Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice

(2010) Lukas W. Pfannenstiel et al.   CELLULAR IMMUNOLOGY

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

(2010) Zhou J. Deng et al.   Nature Nanotechnology

Quantitative analysis of the protein corona on FePt nanoparticles formed by transferrin binding

(2009) X. Jiang et al.   Journal of the Royal Society Interface

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression

(2009) James F Curtin et al.   PLOS MEDICINE

Critical parameters in the pegylation of gold nanoshells for biomedical applications: Anin vitromacrophage study

(2008) James Chen Yong Kah et al.   JOURNAL OF DRUG TARGETING

Pharmacokinetics and Biodistribution of Nanoparticles

(2008) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS