Transcriptome‐wide association study reveals candidate causal genes for lung cancer

Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage

(2019) Jun Xia et al.   CELL

Opportunities and challenges for transcriptome-wide association studies

(2019) Michael Wainberg et al.   NATURE GENETICS

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

(2019) Phuwanat Sakornsakolpat et al.   NATURE GENETICS

Abundant associations with gene expression complicate GWAS follow-up

(2019) Boxiang Liu et al.   NATURE GENETICS

Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics

(2018) Ivana Nedeljkovic et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations

(2018) Maxime Lamontagne et al.   HUMAN MOLECULAR GENETICS

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

(2018) Alexander Gusev et al.   NATURE GENETICS

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

(2018) Alvaro N. Barbeira et al.   Nature Communications

Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN

(2018) Yan-Wei Hu et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

(2017) James D McKay et al.   NATURE GENETICS

Complex Sources of Variation in Tissue Expression Data: Analysis of the GTEx Lung Transcriptome

(2016) Matthew N. McCall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Aquaporin-3 Inhibition Reduces the Growth of NSCLC Cells Induced by Hypoxia

(2016) Shu-Ying Hou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer

(2016) Hua Yuan et al.   Scientific Reports

Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung

(2014) Justin Dang Uy Nguyen et al.   CARCINOGENESIS

Aquaporin 3 knockdown suppresses tumour growth and angiogenesis in experimental non-small cell lung cancer

(2014) Hui Xia et al.   EXPERIMENTAL PHYSIOLOGY

Regulatory effect of iron regulatory protein-2 on iron metabolism in lung cancer

(2014) Z. Cheng et al.   GENETICS AND MOLECULAR RESEARCH

Genome-wide expression quantitative trait loci analysis in asthma

(2013) Yohan Bossé   Current Opinion in Allergy and Clinical Immunology

Interplay of Genetic Risk Factors (CHRNA5-CHRNA3-CHRNB4) and Cessation Treatments in Smoking Cessation Success

(2012) Li-Shiun Chen et al.   AMERICAN JOURNAL OF PSYCHIATRY

Association of the 15q25 and 5p15 Lung Cancer Susceptibility Regions with Gene Expression in Lung Tumor Tissue

(2012) G. Fehringer et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

(2012) Maria N. Timofeeva et al.   HUMAN MOLECULAR GENETICS

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

(2012) Ke Hao et al.   PLoS Genetics

Mutations in NEXN, a Z-Disc Gene, Are Associated with Hypertrophic Cardiomyopathy

(2010) Hu Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Tumorigenic Properties of Iron Regulatory Protein 2 (IRP2) Mediated by Its Specific 73-Amino Acids Insert

(2010) Carmen Maffettone et al.   PLoS One

Toxicological effects of inorganic nanoparticles on human lung cancer A549 cells

(2009) Soo-Jin Choi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Altered iron metabolism, inflammation, transferrin receptors, and ferritin expression in non-small-cell lung cancer

(2009) Suzana Kukulj et al.   MEDICAL ONCOLOGY

Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

(2009) David Hassel et al.   NATURE MEDICINE

Expression profile of early lung adenocarcinoma: identification ofMRP3as a molecular marker for early progression

(2008) S Hanada et al.   JOURNAL OF PATHOLOGY