Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma

PBK/TOPK expression correlates with mutant p53 and affects patients' prognosis and cell proliferation and viability in lung adenocarcinoma

(2015) Bin Lei et al.   HUMAN PATHOLOGY

Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo

(2015) Mrinal Joel et al.   Molecular Cancer

Overexpression of SMYD2 contributes to malignant outcome in gastric cancer

(2014) S Komatsu et al.   BRITISH JOURNAL OF CANCER

Expression of PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK) in human urinary bladder transitional cell carcinoma

(2014) P.K. Singh et al.   IMMUNOBIOLOGY

Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial

(2014) Hansjochen Wilke et al.   LANCET ONCOLOGY

TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis

(2014) Y. Matsuo et al.   Science Translational Medicine

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

(2013) Patrick C O´Leary et al.   BMC CANCER

Overexpression of YWHAZ relates to tumor cell proliferation and malignant outcome of gastric carcinoma

(2013) Y Nishimura et al.   BRITISH JOURNAL OF CANCER

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Novel TOPK Inhibitor HI-TOPK-032 Effectively Suppresses Colon Cancer Growth

(2012) D. J. Kim et al.   CANCER RESEARCH

Overexpression ofTRIM44contributes to malignant outcome in gastric carcinoma

(2012) Kingo Kashimoto et al.   CANCER SCIENCE

Alterations of theTP53Gene in Gastric and Esophageal Carcinogenesis

(2012) Marilanda Ferreira Bellini et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer

(2011) M-C Shih et al.   ONCOGENE

TNM seventh edition: What's new, what's changed

(2010) Leslie H Sobin et al.   CANCER

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

(2010) Yung-Jue Bang et al.   LANCET

PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21

(2010) F Hu et al.   ONCOGENE

Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target

(2009) D Herrero-Martín et al.   BRITISH JOURNAL OF CANCER

Critical roles of T-LAK cell-originated protein kinase in cytokinesis

(2009) Jae-Hyun Park et al.   CANCER SCIENCE

Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma

(2009) Shuhei Komatsu et al.   CARCINOGENESIS

PBK/TOPK in the differential diagnosis of cholangiocarcinoma from hepatocellular carcinoma and its involvement in prognosis of human cholangiocarcinoma

(2009) Furong He et al.   HUMAN PATHOLOGY

Individualization of breast cancer based on histopathological features and molecular alterations

(2008) Hitoshi Tsuda   Breast Cancer