TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer

Invasiveness and anchorage independent growth ability augmented by PTEN inactivation through the PI3K/AKT/NFkB pathway in lung cancer cells

(2011) Hakan Akca et al.   LUNG CANCER

Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data

(2010)   LANCET

PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21

(2010) F Hu et al.   ONCOGENE

Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target

(2009) D Herrero-Martín et al.   BRITISH JOURNAL OF CANCER

Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients

(2009) I Zlobec et al.   BRITISH JOURNAL OF CANCER

Genomic Prognostic Models in Early-Stage Lung Cancer

(2009) Johannes R. Kratz et al.   Clinical Lung Cancer

From Midbody Protein−Protein Interaction Network Construction to Novel Regulators in Cytokinesis

(2009) Tzu-Chi Chen et al.   JOURNAL OF PROTEOME RESEARCH

VEGFA Upregulates FLJ10540 and Modulates Migration and Invasion of Lung Cancer via PI3K/AKT Pathway

(2009) Chang-Han Chen et al.   PLoS One

Post-recurrence survival in completely resected stage I non-small cell lung cancer with local recurrence

(2009) J-J Hung et al.   THORAX

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Adjuvant Paclitaxel Plus Carboplatin Compared With Observation in Stage IB Non–Small-Cell Lung Cancer: CALGB 9633 With the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups

(2008) Gary M. Strauss et al.   JOURNAL OF CLINICAL ONCOLOGY