TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis

Targeted Therapy for Breast Cancer

(2013) Ali Mohamed et al.   AMERICAN JOURNAL OF PATHOLOGY

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

(2013) Patrick C O´Leary et al.   BMC CANCER

Breast cancer statistics, 2013

(2013) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Incisive Imaging and Computation for Cellular Mysteries: Lessons from Abscission

(2013) Natalie Elia et al.   CELL

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Novel TOPK Inhibitor HI-TOPK-032 Effectively Suppresses Colon Cancer Growth

(2012) D. J. Kim et al.   CANCER RESEARCH

Inhibitors Targeting Mitosis: Tales of How Great Drugs against a Promising Target Were Brought Down by a Flawed Rationale

(2012) E. Komlodi-Pasztor et al.   CLINICAL CANCER RESEARCH

Phosphorylation of IκBα at Serine 32 by T-lymphokine-activated Killer Cell-originated Protein Kinase Is Essential for Chemoresistance against Doxorubicin in Cervical Cancer Cells

(2012) Jung-Hwan Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Cancer stromal targeting (CAST) therapy

(2011) Yasuhiro Matsumura   ADVANCED DRUG DELIVERY REVIEWS

Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy

(2011) Ming-Kung Yeh et al.   International Journal of Nanomedicine

T-LAK Cell-originated Protein Kinase (TOPK) Phosphorylation of MKP1 Protein Prevents Solar Ultraviolet Light-induced Inflammation through Inhibition of the p38 Protein Signaling Pathway

(2011) Shengqing Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

(2011) Theonie Anastassiadis et al.   NATURE BIOTECHNOLOGY

Tumor control versus adverse events with targeted anticancer therapies

(2011) Dorothy M. K. Keefe et al.   Nature Reviews Clinical Oncology

TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer

(2011) M-C Shih et al.   ONCOGENE

Using a Stem Cell-Based Signature to Guide Therapeutic Selection in Cancer

(2010) I. Shats et al.   CANCER RESEARCH

Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells

(2010) Chikako Fukukawa et al.   GENES CHROMOSOMES & CANCER

PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21

(2010) F Hu et al.   ONCOGENE

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Critical roles of T-LAK cell-originated protein kinase in cytokinesis

(2009) Jae-Hyun Park et al.   CANCER SCIENCE

Downregulation of Signal Transducer and Activator of Transcription 5 (STAT5) in CD34+Cells Promotes Megakaryocytic Development, Whereas Activation of STAT5 Drives Erythropoiesis

(2008) Sandra G. Olthof et al.   STEM CELLS