Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent

Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II

(2017) Christoph Maier et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Angiotensin-converting enzyme 2 amplification limited to the circulation does not protect mice from development of diabetic nephropathy

(2017) Jan Wysocki et al.   KIDNEY INTERNATIONAL

A Fluorometric Method of Measuring Carboxypeptidase Activities for Angiotensin II and Apelin-13

(2017) Pan Liu et al.   Scientific Reports

Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney

(2016) Oliver Domenig et al.   Scientific Reports

Plasma and Kidney Angiotensin Peptides: Importance of the Aminopeptidase A/Angiotensin III Axis

(2015) Jan Wysocki et al.   AMERICAN JOURNAL OF HYPERTENSION

The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients

(2015) Jofre Tenorio-Laranga et al.   Journal of Neuroinflammation

New Components of the Renin-Angiotensin System: Alamandine and the Mas-Related G Protein-Coupled Receptor D

(2014) Gisele Maia Etelvino et al.   CURRENT HYPERTENSION REPORTS

Angiotensin-Converting Enzyme 2–Independent Action of Presumed Angiotensin-Converting Enzyme 2 Activators

(2014) Philipp K. Haber et al.   HYPERTENSION

A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation

(2014) A. Gaggar et al.   JOURNAL OF IMMUNOLOGY

Update on the Angiotensin Converting Enzyme 2-Angiotensin (1–7)-Mas Receptor Axis: Fetal Programing, Sex Differences, and Intracellular Pathways

(2014) Mark C. Chappell et al.   Frontiers in Endocrinology

Predominance of AT1 Blockade Over Mas–Mediated Angiotensin-(1–7) Mechanisms in the Regulation of Blood Pressure and Renin–Angiotensin System in mRen2.Lewis Rats

(2013) Jasmina Varagic et al.   AMERICAN JOURNAL OF HYPERTENSION

Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry

(2013) Nadja Grobe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis

(2013) Yiqin Zuo et al.   KIDNEY INTERNATIONAL

Angiotensin-(1–7) in kidney disease: a review of the controversies

(2012) Danielle Zimmerman et al.   CLINICAL SCIENCE

Murine Recombinant Angiotensin-Converting Enzyme 2

(2012) Minghao Ye et al.   HYPERTENSION

Distribution of Prolyl Oligopeptidase in Human Peripheral Tissues and in Ovarian and Colorectal Tumors

(2012) Timo T. Myöhänen et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Prolyl oligopeptidase induces angiogenesis bothin vitroandin vivoin a novel regulatory manner

(2010) TT Myöhänen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibitors of Prolyl Oligopeptidases for the Therapy of Human Diseases: Defining Diseases and Inhibitors

(2010) Janice Lawandi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting the Degradation of Angiotensin II With Recombinant Angiotensin-Converting Enzyme 2

(2009) Jan Wysocki et al.   HYPERTENSION

Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen

(2009) Philip J. O'Reilly et al.   JOURNAL OF NEUROIMMUNOLOGY

Characterization of membrane-bound prolyl endopeptidase from brain

(2008) Jofre Tenorio-Laranga et al.   FEBS Journal

Cellular and subcellular distribution of rat brain prolyl oligopeptidase and its association with specific neuronal neurotransmitters

(2008) Timo T. Myöhänen et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Prolyl oligopeptidase stimulates the aggregation of α-synuclein

(2008) Inger Brandt et al.   PEPTIDES