Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer’s disease

TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

(2017) Maria Cristina Marrone et al.   Nature Communications

TRPV1 Regulates Stress Responses through HDAC2

(2017) Sung Eun Wang et al.   Cell Reports

The Role of Aβ-Induced Calcium Dysregulation in the Pathogenesis of Alzheimer's Disease

(2017) David H. Small et al.   JOURNAL OF ALZHEIMERS DISEASE

Evaluation of the antidepressant- and anxiolytic-like activity of α-spinasterol, a plant derivative with TRPV1 antagonistic effects, in mice

(2016) Katarzyna Socała et al.   BEHAVIOURAL BRAIN RESEARCH

Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways

(2016) Jisung Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus

(2016) Moonseok Choi et al.   Molecular Brain

Die Another Day: A Painless Path to Longevity

(2014) Sophie M. Steculorum et al.   CELL

TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling

(2014) Céline E. Riera et al.   CELL

Acute Heat-Evoked Temperature Sensation Is Impaired but Not Abolished in Mice Lacking TRPV1 and TRPV3 Channels

(2014) Irène Marics et al.   PLoS One

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice

(2014) V Gatta et al.   Cell Death & Disease

TRPV1: A Potential Drug Target for Treating Various Diseases

(2014) Rafael Brito et al.   Cells

Calcium channel blockers and dementia

(2013) V Nimmrich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner

(2013) Yue Wang et al.   NEUROBIOLOGY OF AGING

TRPV1 Activation in Primary Cortical Neurons Induces Calcium-Dependent Programmed Cell Death

(2013) Juhyun Song et al.   Experimental Neurobiology

Ryanodine Receptor Blockade Reduces Amyloid-  Load and Memory Impairments in Tg2576 Mouse Model of Alzheimer Disease

(2012) B. Oules et al.   JOURNAL OF NEUROSCIENCE

Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice

(2012) Jun Peng et al.   NEUROSCIENCE LETTERS

Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine

(2011) Thimmappa S. Anekonda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The absence of the calcium-buffering protein calbindin is associated with faster age-related decline in hippocampal metabolism

(2011) Herman Moreno et al.   HIPPOCAMPUS

New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc

(2011) C Corona et al.   Cell Death & Disease

The dysregulation of intracellular calcium in Alzheimer disease

(2010) Charlene Supnet et al.   CELL CALCIUM

SDS-PAGE/Immunoblot Detection of Aβ Multimers in Human Cortical Tissue Homogenates using Antigen-Epitope Retrieval

(2010) Rebecca F. Rosen et al.   Jove-Journal of Visualized Experiments

Functional emergence of the hippocampus in context fear learning in infant rats

(2009) Charlis Raineki et al.   HIPPOCAMPUS

Deviant Ryanodine Receptor-Mediated Calcium Release Resets Synaptic Homeostasis in Presymptomatic 3xTg-AD Mice

(2009) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

TRPV1 stimulation triggers apoptotic cell death of rat cortical neurons

(2008) Hisashi Shirakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

(2008) King-Ho Cheung et al.   NEURON