TRPV1: A Potential Drug Target for Treating Various Diseases

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Role of CXCR2 and TRPV1 in functional, inflammatory and behavioural changes in the rat model of cyclophosphamide-induced haemorrhagic cystitis

(2013) Fabiana N Dornelles et al.   BRITISH JOURNAL OF PHARMACOLOGY

Transient receptor potential vanilloid-2 mediates the effects of transient heat shock on endocytosis of human monocyte-derived dendritic cells

(2013) Attila Gábor Szöllősi et al.   FEBS LETTERS

Cyclophosphamide-induced cystitis reduces ASIC channel but enhances TRPV1 receptor function in rat bladder sensory neurons

(2013) Khoa Dang et al.   JOURNAL OF NEUROPHYSIOLOGY

Dynamic and Permissive Roles of TRPV1 and TRPV4 Channels for Thermosensation in Mouse Supraoptic Magnocellular Neurosecretory Neurons

(2013) Jessica R. Sudbury et al.   JOURNAL OF NEUROSCIENCE

The role of endogenous molecules in modulating pain through transient receptor potential vanilloid 1 (TRPV1)

(2013) Sara L. Morales-Lázaro et al.   JOURNAL OF PHYSIOLOGY-LONDON

Increased mRNA Expression of Genes Involved in Pronociceptive Inflammatory Reactions in Bladder Tissue of Interstitial Cystitis

(2013) Yukio Homma et al.   JOURNAL OF UROLOGY

Alteration in TRPV1 and Muscarinic (M3) receptor expression and function in idiopathic overactive bladder urothelial cells

(2012) L. A. Birder et al.   Acta Physiologica

TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors

(2012) Tina Marie Lieu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Quantitative analysis of TRP channel genes in mouse organs

(2012) Yongwoo Jang et al.   ARCHIVES OF PHARMACAL RESEARCH

Cyclin-Dependent Kinase 5 Controls TRPV1 Membrane Trafficking and the Heat Sensitivity of Nociceptors through KIF13B

(2012) B.-M. Xing et al.   JOURNAL OF NEUROSCIENCE

TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammation

(2012) Roxanne Y. Walder et al.   PAIN

Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors

(2012) A. M. Gregus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient receptor potential genes, smoking, occupational exposures and cough in adults

(2012) Lidwien AM Smit et al.   RESPIRATORY RESEARCH

Rat detrusor overactivity induced by chronic spinalization can be abolished by a transient receptor potential vanilloid 1 (TRPV1) antagonist

(2011) André Santos-Silva et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

The thermo-TRP ion channel family: properties and therapeutic implications

(2011) Laura Vay et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cough reflex sensitivity is increased in guinea pigs with parainfluenza virus infection

(2011) X. M. Ye et al.   EXPERIMENTAL LUNG RESEARCH

Heteromeric Heat-sensitive Transient Receptor Potential Channels Exhibit Distinct Temperature and Chemical Response

(2011) Wei Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation

(2011) T Kaur et al.   Cell Death & Disease

NOX3 NADPH Oxidase Couples Transient Receptor Potential Vanilloid 1 to Signal Transducer and Activator of Transcription 1-Mediated Inflammation and Hearing Loss

(2010) Debashree Mukherjea et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of capsaicin on potassium conductance and electromotility of the guinea pig outer hair cell

(2010) T. Wu et al.   HEARING RESEARCH

Loss of Function of Transient Receptor Potential Vanilloid 1 (TRPV1) Genetic Variant Is Associated with Lower Risk of Active Childhood Asthma

(2010) Gerard Cantero-Recasens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thermosensitive transient receptor potential channels in human corneal epithelial cells

(2010) Stefan Mergler et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Analgesic potential of TRPV1 antagonists

(2009) Philip R. Kym et al.   BIOCHEMICAL PHARMACOLOGY

Sex differences in the expression profile of acid-sensing ion channels in the mouse urinary bladder: a possible involvement in irritative bladder symptoms

(2009) Hideki Kobayashi et al.   BJU INTERNATIONAL

An Update on the Pharmacological Management of Post-Herpetic Neuralgia and Painful Diabetic Neuropathy

(2009) Che S Zin et al.   CNS DRUGS

Vanilloid Receptor Antagonists: Emerging Class of Novel Anti-Inflammatory Agents for Pain Management

(2009) Manojit Pal et al.   CURRENT PHARMACEUTICAL DESIGN

Transient receptor potential vanilloid-1 signaling inhibits differentiation and activation of human dendritic cells

(2009) Balázs I. Tóth et al.   FEBS LETTERS

TRPV1 Is Activated by Both Acidic and Basic pH

(2009) A. Dhaka et al.   JOURNAL OF NEUROSCIENCE

Selective Pharmacological Blockade of the TRPV1 Receptor Suppresses Sensory Reflexes of the Rodent Bladder

(2009) Joseph S. Cefalu et al.   JOURNAL OF UROLOGY

Pharmacology of Vanilloid Transient Receptor Potential Cation Channels

(2009) J. Vriens et al.   MOLECULAR PHARMACOLOGY

Behavioral assessment and identification of a molecular marker in a salicylate-induced tinnitus in rats

(2009) K. Kizawa et al.   NEUROSCIENCE

Changes in transient receptor potential vanilloid (TRPV) 1, 2, 3 and 4 expression in mouse inner ear following gentamicin challenge

(2008) Takuya Ishibashi et al.   ACTA OTO-LARYNGOLOGICA

Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks

(2008) Gilbert Y. Wong et al.   BRAIN RESEARCH REVIEWS

Recent Progress in the Development of Selective TRPV1 Antagonists for Pain

(2008) Lisa Broad et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Differential Localizations of the Transient Receptor Potential Channels TRPV4 and TRPV1 in the Mouse Urinary Bladder

(2008) Takahiro Yamada et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Short Interfering RNA against Transient Receptor Potential Vanilloid 1 Attenuates Cisplatin-Induced Hearing Loss in the Rat

(2008) D. Mukherjea et al.   JOURNAL OF NEUROSCIENCE

Altered expression of TRPV1 and sensitivity to capsaicin in pulmonary myelinated afferents following chronic airway inflammation in the rat

(2008) Guangfan Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Actions of 3-methyl-N-oleoyldopamine, 4-methyl-N-oleoyldopamine and N-oleoylethanolamide on the rat TRPV1 receptor in vitro and in vivo

(2008) Róbert Almási et al.   LIFE SCIENCES

Influence of TRPV1 on Diabetes-Induced Alterations in Thermal Pain Sensitivity

(2008) Reddy M Pabbidi et al.   Molecular Pain

Lack of TRPV1 inhibits cystitis-induced increased mechanical sensitivity in mice

(2008) Zun-Yi Wang et al.   PAIN