Astrocytic expression of ZIP14 (SLC39A14) is part of the inflammatory reaction in chronic neurodegeneration with iron overload

SLC39A14 deficiency alters manganese homeostasis and excretion resulting in brain manganese accumulation and motor deficits in mice

(2018) Supak Jenkitkasemwong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels

(2017) Jacob Sterling et al.   EXPERIMENTAL EYE RESEARCH

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Metal Transporter Zip14 ( Slc39a14 ) Deletion in Mice Increases Manganese Deposition and Produces Neurotoxic Signatures and Diminished Motor Activity

(2017) Tolunay Beker Aydemir et al.   JOURNAL OF NEUROSCIENCE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Modelling iron mismanagement in neurodegenerative disease in vitro : paradigms, pitfalls, possibilities & practical considerations

(2017) Sinead Healy et al.   PROGRESS IN NEUROBIOLOGY

The role of interleukin-6 signaling in nervous tissue

(2016) Michelle Rothaug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Aging amplifies multiple phenotypic defects in mice with zinc transporter Zip14 (Slc39a14) deletion

(2016) Tolunay Beker Aydemir et al.   EXPERIMENTAL GERONTOLOGY

Inflammatory Response in the CNS: Friend or Foe?

(2016) Marta Sochocka et al.   MOLECULAR NEUROBIOLOGY

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism–dystonia

(2016) Karin Tuschl et al.   Nature Communications

Molecular mechanisms of non-transferrin-bound and transferring-bound iron uptake in primary hippocampal neurons

(2015) Changyi Ji et al.   JOURNAL OF NEUROCHEMISTRY

Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

(2015) Maj Schneider Thomsen et al.   NEUROBIOLOGY OF DISEASE

Analysis of IL-6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M

(2014) Meng-Ping Hsu et al.   GLIA

Iron dysregulation in Huntington's disease

(2014) Michelle Muller et al.   JOURNAL OF NEUROCHEMISTRY

Interleukin-6 enhances manganese accumulation in SH-SY5Y cells: implications of the up-regulation of ZIP14 and the down-regulation of ZnT10

(2014) Hitomi Fujishiro et al.   Metallomics

An iron-regulated and glycosylation-dependent proteasomal degradation pathway for the plasma membrane metal transporter ZIP14

(2014) N. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron uptake in quiescent and inflammation-activated astrocytes: A potentially neuroprotective control of iron burden

(2013) Ilaria Pelizzoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration

(2013) Hjalte Holm Andersen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders

(2013) H. Nam et al.   HAEMATOLOGICA

Regulation of CCL20 expression in astrocytes by IL-6 and IL-17

(2012) Gordon P. Meares et al.   GLIA

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron

(2011) Jorge J. Pinilla-Tenas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Pathogenic implications of iron accumulation in multiple sclerosis

(2011) Rachel Williams et al.   JOURNAL OF NEUROCHEMISTRY

ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin

(2010) Ningning Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic accumulation of iron and zinc by cultured astrocytes

(2010) Glenda M. Bishop et al.   JOURNAL OF NEURAL TRANSMISSION

Inflammation and gliosis in neurological diseases – clinical implications

(2010) Anna Członkowska et al.   JOURNAL OF NEUROIMMUNOLOGY

Accumulation of Non-Transferrin-Bound Iron by Neurons, Astrocytes, and Microglia

(2010) Glenda M. Bishop et al.   NEUROTOXICITY RESEARCH

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Interleukin-1β contributes via nitric oxide to the upregulation and functional activity of the zinc transporter Zip14 (Slc39a14) in murine hepatocytes

(2009) Louis A. Lichten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A potential pathogenetic role of iron in Alzheimer's disease

(2008) Laura Silvestri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE