Microglial cell‐derived interleukin‐6 influences behavior and inflammatory response in the brain following traumatic brain injury

Different responses to a high-fat diet in IL-6 conditional knock-out mice driven by constitutive GFAP-Cre and Synapsin 1-Cre expression

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Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies

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Interleukin-6: designing specific therapeutics for a complex cytokine

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Detecting and Avoiding Problems When Using the Cre–lox System

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Immune cells and CNS physiology: Microglia and beyond

(2018) Geoffrey T. Norris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species

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The role of the immunoproteasome in interferon-γ-mediated microglial activation

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Microglia in the TBI brain: The good, the bad, and the dysregulated

(2016) David J. Loane et al.   EXPERIMENTAL NEUROLOGY

Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammation

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Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury

(2016) A. Erturk et al.   JOURNAL OF NEUROSCIENCE

Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury

(2016) Alok Kumar et al.   JOURNAL OF NEUROTRAUMA

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proangiogenic Properties of Thrombospondin-4Significance

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Acute CSF interleukin-6 trajectories after TBI: Associations with neuroinflammation, polytrauma, and outcome

(2015) R.G. Kumar et al.   BRAIN BEHAVIOR AND IMMUNITY

Astrocytic IL-6 mediates locomotor activity, exploration, anxiety, learning and social behavior

(2015) Maria Erta et al.   HORMONES AND BEHAVIOR

Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury

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Early inflammatory mediator gene expression in two models of traumatic brain injury: ex vivo cortical slice in mice and in vivo cortical impact in piglets

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ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

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Interleukin-6 deletion in mice driven by aP2-Cre-ERT2 prevents against high-fat diet-induced gain weight and adiposity in female mice

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Genetic targeting of microglia

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A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Animal models of traumatic brain injury

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Microglia: New Roles for the Synaptic Stripper

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Plasticity Response in the Contralesional Hemisphere after Subtle Neurotrauma: Gene Expression Profiling after Partial Deafferentation of the Hippocampus

(2013) Daniel Andersson et al.   PLoS One

Astrocyte-specific deficiency of interleukin-6 and its receptor reveal specific roles in survival, body weight and behavior

(2012) Albert Quintana et al.   BRAIN BEHAVIOR AND IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

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Interleukin-6, a Major Cytokine in the Central Nervous System

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NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Interleukin-6 Regulates the Expression of Hypothalamic Neuropeptides Involved in Body Weight in a Gender-Dependent Way

(2011) R. M. Señarís et al.   JOURNAL OF NEUROENDOCRINOLOGY

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

IL6 Deficiency Affects Function After Traumatic Brain Injury

(2011) Eric J. Ley et al.   JOURNAL OF SURGICAL RESEARCH

Resistin enhances the expansion of regulatory T cells through modulation of dendritic cells

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The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

Interleukin-6 as a key player in systemic inflammation and joint destruction

(2009) J.E. Fonseca et al.   AUTOIMMUNITY REVIEWS

Impaired hippocampus-dependent and -independent learning in IL-6 deficient mice

(2009) Paul Christian Baier et al.   BEHAVIOURAL BRAIN RESEARCH

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

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Site-Specific Production of IL-6 in the Central Nervous System Retargets and Enhances the Inflammatory Response in Experimental Autoimmune Encephalomyelitis

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In Situ Detection of Inflammatory Mediators in Post Mortem Human Brain Tissue after Traumatic Injury

(2009) Tony Frugier et al.   JOURNAL OF NEUROTRAUMA

Cell-type-specific isolation of ribosome-associated mRNA from complex tissues

(2009) E. Sanz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central Resistin Regulates Hypothalamic and Peripheral Lipid Metabolism in a Nutritional-Dependent Fashion

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Redefining the Role of Metallothionein within the Injured Brain

(2008) Roger S. Chung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of CX3CR1 (Fractalkine Receptor) in Brain Damage and Inflammation Induced by Focal Cerebral Ischemia in Mouse

(2008) Ádám Dénes et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria

(2008) Daniel Degrandi et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury

(2008) Charlotte Israelsson et al.   JOURNAL OF NEUROTRAUMA

Traumatic brain injury induces adipokine gene expression in rat brain

(2008) Russell Brown et al.   NEUROSCIENCE LETTERS

Effect of astrocyte-targeted production of IL-6 on traumatic brain injury and its impact on the cortical transcriptome

(2007) Albert Quintana et al.   Developmental Neurobiology