Translational bioinformatics in the era of real-time biomedical, health care and wellness data streams

The hundred person wellness project and Google’s baseline study: medical revolution or unnecessary and potentially harmful over-testing?

(2015) Eleftherios P Diamandis   BMC Medicine

Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits

(2015) P. Darrell Neufer et al.   Cell Metabolism

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Providing Time-Discrete Gait Information by Wearable Feedback Apparatus for Lower-Limb Amputees: Usability and Functional Validation

(2015) Simona Crea et al.   IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING

GSK collaborates with Apple on ResearchKit

(2015) Michael Eisenstein   NATURE BIOTECHNOLOGY

Methods of integrating data to uncover genotype–phenotype interactions

(2015) Marylyn D. Ritchie et al.   NATURE REVIEWS GENETICS

Public Health in the Precision-Medicine Era

(2015) Ronald Bayer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Precision Medicine — Personalized, Problematic, and Promising

(2015) J. Larry Jameson et al.   NEW ENGLAND JOURNAL OF MEDICINE

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

Financing translation: Analysis of the NCATS rare-diseases portfolio

(2015) David E. Fagnan et al.   Science Translational Medicine

Precision medicine: Beyond the inflection point

(2015) Sam Hawgood et al.   Science Translational Medicine

The emerging field of mobile health

(2015) Steven R. Steinhubl et al.   Science Translational Medicine

A targeted real-time early warning score (TREWScore) for septic shock

(2015) Katharine E. Henry et al.   Science Translational Medicine

Identification of type 2 diabetes subgroups through topological analysis of patient similarity

(2015) Li Li et al.   Science Translational Medicine

Creating a Common Data Model for Comparative Effectiveness with the Observational Medical Outcomes Partnership

(2015) F.S. Resnic et al.   Applied Clinical Informatics

mActive: A Randomized Clinical Trial of an Automated mHealth Intervention for Physical Activity Promotion

(2015) S. S. Martin et al.   Journal of the American Heart Association

Driving Innovation in Health Systems through an Apps-Based Information Economy

(2015) Kenneth D. Mandl et al.   Cell Systems

A Stock Market Forecasting Model Combining Two-Directional Two-Dimensional Principal Component Analysis and Radial Basis Function Neural Network

(2015) Zhiqiang Guo et al.   PLoS One

Invited Commentary: Observational Research in the Age of the Electronic Health Record

(2014) C. G. Chute   AMERICAN JOURNAL OF EPIDEMIOLOGY

The Placental Exposome: Placental Determinants of Fetal Adiposity and Postnatal Body Composition

(2014) R.M. Lewis et al.   ANNALS OF NUTRITION AND METABOLISM

Individualized Medicine from Prewomb to Tomb

(2014) Eric J. Topol   CELL

Quantified self and human movement: A review on the clinical impact of wearable sensing and feedback for gait analysis and intervention

(2014) Pete B. Shull et al.   GAIT & POSTURE

Big Data In Health: A New Era For Research And Patient Care

(2014) Alan R. Weil   HEALTH AFFAIRS

Creating Value In Health Care Through Big Data: Opportunities And Policy Implications

(2014) Joachim Roski et al.   HEALTH AFFAIRS

Big Data In Health Care: Using Analytics To Identify And Manage High-Risk And High-Cost Patients

(2014) David W. Bates et al.   HEALTH AFFAIRS

Unobtrusive Sensing and Wearable Devices for Health Informatics

(2014) Ya-Li Zheng et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Clinical Interpretation and Implications of Whole-Genome Sequencing

(2014) Frederick E. Dewey et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Personalized Coaching Systems to support healthy behavior in people with chronic conditions

(2014) H. Hermens et al.   JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY

Fraud in a population-based study of headache: prevention, detection and correction

(2014) Bilal Ahmed et al.   JOURNAL OF HEADACHE AND PAIN

Disposable Biosensors for Clinical Diagnosis

(2014) Bruno Campos Janegitz et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Assessment of biofeedback rehabilitation in post-stroke patients combining fMRI and gait analysis: a case study

(2014) Silvia Del Din et al.   Journal of NeuroEngineering and Rehabilitation

Wearable accelerometry-based technology capable of assessing functional activities in neurological populations in community settings: a systematic review

(2014) Dax Steins et al.   Journal of NeuroEngineering and Rehabilitation

D-62 Thematic Poster - Physical Activity Interventions

(2014) &NA;   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Guidelines for investigating causality of sequence variants in human disease

(2014) D. G. MacArthur et al.   NATURE

FDA Regulation of Mobile Health Technologies

(2014) Nathan G. Cortez et al.   NEW ENGLAND JOURNAL OF MEDICINE

Patient-centered interventions to improve medication management and adherence: A qualitative review of research findings

(2014) Jennifer L. Kuntz et al.   PATIENT EDUCATION AND COUNSELING

Automated Detection of Off-Label Drug Use

(2014) Kenneth Jung et al.   PLoS One

Soft Microfluidic Assemblies of Sensors, Circuits, and Radios for the Skin

(2014) S. Xu et al.   SCIENCE

Disease Risk Factors Identified Through Shared Genetic Architecture and Electronic Medical Records

(2014) L. Li et al.   Science Translational Medicine

Biobanks and Electronic Medical Records: Enabling Cost-Effective Research

(2014) E. Bowton et al.   Science Translational Medicine

Survey on Fall Detection and Fall Prevention Using Wearable and External Sensors

(2014) Yueng Delahoz et al.   SENSORS

The exposome: a new paradigm to study the impact of environment on health

(2014) Martine Vrijheid   THORAX

Effect of Neurofeedback and Electromyographic-Biofeedback Therapy on Improving Hand Function in Stroke Patients

(2014) S. M. Rayegani et al.   Topics in Stroke Rehabilitation

Non-invasive wearable electrochemical sensors: a review

(2014) Amay J. Bandodkar et al.   TRENDS IN BIOTECHNOLOGY

Body-Monitoring and Health Supervision by Means of Optical Fiber-Based Sensing Systems in Medical Textiles

(2014) Brit M. Quandt et al.   Advanced Healthcare Materials

Enabling multiscale modeling in systems medicine

(2014) Olaf Wolkenhauer et al.   Genome Medicine

Predictive Monitoring of Mobile Patients by Combining Clinical Observations With Data From Wearable Sensors

(2014) Lei Clifton et al.   IEEE Journal of Biomedical and Health Informatics

Biofeedback-based training for stress management in daily hassles: an intervention study

(2014) Yuka Kotozaki et al.   Brain and Behavior

Bringing precision medicine to the clinic: from genomic profiling to the power of clinical observation

(2013) J. Baselga   ANNALS OF ONCOLOGY

A self-updating road map of The Cancer Genome Atlas

(2013) D. E. Robbins et al.   BIOINFORMATICS

Predicting out of intensive care unit cardiopulmonary arrest or death using electronic medical record data

(2013) Carlos A Alvarez et al.   BMC Medical Informatics and Decision Making

iPOP Goes the World: Integrated Personalized Omics Profiling and the Road toward Improved Health Care

(2013) Jennifer Li-Pook-Than et al.   CHEMISTRY & BIOLOGY

The CLIPMERGE PGx Program: Clinical Implementation of Personalized Medicine Through Electronic Health Records and Genomics–Pharmacogenomics

(2013) O Gottesman et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Measuring the exposome: A powerful basis for evaluating environmental exposures and cancer risk

(2013) Christopher P. Wild et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Blood pressure regulation: every adaptation is an integration?

(2013) Michael J. Joyner et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

The arrival of genomic medicine to the clinic is only the beginning of the journey

(2013) James P. Evans et al.   GENETICS IN MEDICINE

Implementing genomic medicine in the clinic: the future is here

(2013) Teri A. Manolio et al.   GENETICS IN MEDICINE

Some experiences and opportunities for big data in translational research

(2013) Christopher G. Chute et al.   GENETICS IN MEDICINE

The promise of wearable activity sensors to define patient recovery

(2013) Geoff Appelboom et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Smart Health Monitoring Systems: An Overview of Design and Modeling

(2013) Mirza Mansoor Baig et al.   JOURNAL OF MEDICAL SYSTEMS

Quantifying light exposure patterns in young adult students

(2013) Amanda A. Alvarez et al.   JOURNAL OF MODERN OPTICS

Validation of the Fitbit One activity monitor device during treadmill walking

(2013) Judit Takacs et al.   JOURNAL OF SCIENCE AND MEDICINE IN SPORT

Exposome informatics: considerations for the design of future biomedical research information systems

(2013) Fernando Martin Sanchez et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

The big challenges of big data

(2013) Vivien Marx   NATURE

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

NCBI’s Database of Genotypes and Phenotypes: dbGaP

(2013) Kimberly A. Tryka et al.   NUCLEIC ACIDS RESEARCH

Feasibility of an Ingestible Sensor-Based System for Monitoring Adherence to Tuberculosis Therapy

(2013) Robert Belknap et al.   PLoS One

Biosensors in Clinical Practice: Focus on Oncohematology

(2013) Nicola Fracchiolla et al.   SENSORS

Data Mining for Wearable Sensors in Health Monitoring Systems: A Review of Recent Trends and Challenges

(2013) Hadi Banaee et al.   SENSORS

Remote monitoring of patients with implanted devices: data exchange and integration

(2013) Enno T Van der Velde et al.   European Journal of Preventive Cardiology

Phenome-Wide Association Study (PheWAS) for Detection of Pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

(2013) Sarah A. Pendergrass et al.   PLoS Genetics

Wearable Monitoring for Mood Recognition in Bipolar Disorder Based on History-Dependent Long-Term Heart Rate Variability Analysis

(2013) Gaetano Valenza et al.   IEEE Journal of Biomedical and Health Informatics

Translational Bioinformatics Approaches to Drug Development

(2013) Ben Readhead et al.   Advances in Wound Care

Smart wearable systems: Current status and future challenges

(2012) Marie Chan et al.   ARTIFICIAL INTELLIGENCE IN MEDICINE

A new sensor for the assessment of personal exposure to volatile organic compounds

(2012) Cheng Chen et al.   ATMOSPHERIC ENVIRONMENT

SEQanswers: an open access community for collaboratively decoding genomes

(2012) Jing-Woei Li et al.   BIOINFORMATICS

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

(2012) Rui Chen et al.   CELL

Role for direct electronic verification of pharmaceutical ingestion in pharmaceutical development

(2012) Lorenzo A. DiCarlo   Contemporary Clinical Trials

Wearable Electrochemical Sensors and Biosensors: A Review

(2012) Joshua Ray Windmiller et al.   ELECTROANALYSIS

Comparison of Next-Generation Sequencing Systems

(2012) Lin Liu et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Importance of Health Information Technology, Electronic Health Records, and Continuously Aggregating Data to Comparative Effectiveness Research and Learning Health Care

(2012) Benjamin J. Miriovsky et al.   JOURNAL OF CLINICAL ONCOLOGY

Early detection of impending physiologic deterioration among patients who are not in intensive care: Development of predictive models using data from an automated electronic medical record

(2012) Gabriel J. Escobar et al.   Journal of Hospital Medicine

A review of wearable sensors and systems with application in rehabilitation

(2012) Shyamal Patel et al.   Journal of NeuroEngineering and Rehabilitation

The coming age of data-driven medicine: translational bioinformatics' next frontier

(2012) N. H. Shah et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Mining electronic health records: towards better research applications and clinical care

(2012) Peter B. Jensen et al.   NATURE REVIEWS GENETICS

Preparing for Precision Medicine

(2012) Reza Mirnezami et al.   NEW ENGLAND JOURNAL OF MEDICINE

BioGPS and MyGene.info: organizing online, gene-centric information

(2012) Chunlei Wu et al.   NUCLEIC ACIDS RESEARCH

A Review on Architectures and Communications Technologies for Wearable Health-Monitoring Systems

(2012) Víctor Custodio et al.   SENSORS

Integration of data from remote monitoring systems and programmers into the hospital electronic health record system based on international standards

(2012) E. T. van der Velde et al.   Netherlands Heart Journal

Proteome-Wide Analysis of Disease-Associated SNPs That Show Allele-Specific Transcription Factor Binding

(2012) Falk Butter et al.   PLoS Genetics

A contact lens with embedded sensor for monitoring tear glucose level

(2011) Huanfen Yao et al.   BIOSENSORS & BIOELECTRONICS

Stable expression of FRET biosensors: A new light in cancer research

(2011) Kazuhiro Aoki et al.   CANCER SCIENCE

Predicting and Preventing Sudden Cardiac Death

(2011) N.A. Mark Estes   CIRCULATION

A prescription fraud detection model

(2011) Karca Duru Aral et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Mobility Support for Health Monitoring at Home Using Wearable Sensors

(2011) Sergio González-Valenzuela et al.   IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE

Accuracy Of Fitbit Activity Monitor To Predict Energy Expenditure With And Without Classification Of Activities

(2011) Kathryn L. Dannecker et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Data transformation practices in biomedical sciences

(2011) Mihai Valcu et al.   NATURE METHODS

Using electronic health records to drive discovery in disease genomics

(2011) Isaac S. Kohane   NATURE REVIEWS GENETICS

WikiPathways: building research communities on biological pathways

(2011) T. Kelder et al.   NUCLEIC ACIDS RESEARCH

Gene Expression Atlas update--a value-added database of microarray and sequencing-based functional genomics experiments

(2011) M. Kapushesky et al.   NUCLEIC ACIDS RESEARCH

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

3DSwap: curated knowledgebase of proteins involved in 3D domain swapping

(2011) K. Shameer et al.   Database-The Journal of Biological Databases and Curation

BioStar: An Online Question & Answer Resource for the Bioinformatics Community

(2011) Laurence D. Parnell et al.   PLoS Computational Biology

Sudden Cardiac Death Prediction and Prevention

(2010) Glenn I. Fishman et al.   CIRCULATION

Contributions of remote monitoring to the follow-up of implantable cardioverter-defibrillator leads under advisory

(2010) L. Guedon-Moreau et al.   EUROPEAN HEART JOURNAL

Desquamative interstitial pneumonia

(2010) Henry D Tazelaar et al.   HISTOPATHOLOGY

Prognosis—A Wearable Health-Monitoring System for People at Risk: Methodology and Modeling

(2010) Alexandros Pantelopoulos et al.   IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE

Effectiveness of telemedicine: A systematic review of reviews

(2010) Anne G. Ekeland et al.   INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS

Novel monitor paradigm for real-time exposure assessment

(2010) Indira Negi et al.   Journal of Exposure Science and Environmental Epidemiology

Cost savings and safety of ICD remote control by telephone: a prospective, observational study

(2010) Olympia Bikou et al.   JOURNAL OF TELEMEDICINE AND TELECARE

Expanding Risk-Profiling Strategies for Prediction and Prevention of Sudden Cardiac Death**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

(2010) Robert J. Myerburg et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Self-Monitoring in Weight Loss: A Systematic Review of the Literature

(2010) Lora E. Burke et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Leveraging informatics for genetic studies: use of the electronic medical record to enable a genome-wide association study of peripheral arterial disease

(2010) Iftikhar J Kullo et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Clinical assessment incorporating a personal genome

(2010) Euan A Ashley et al.   LANCET

In silico research in the era of cloud computing

(2010) Joel T Dudley et al.   NATURE BIOTECHNOLOGY

Strategies for treating idiopathic pulmonary fibrosis

(2010) R. M. du Bois   NATURE REVIEWS DRUG DISCOVERY

The Path to Personalized Medicine

(2010) Margaret A. Hamburg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wearable Sensor Glove Based on Conducting Fabric Using Electrodermal Activity and Pulse-Wave Sensors for e-Health Application

(2010) Youngbum Lee et al.   Telemedicine and e-Health

A Wearable and Wireless Sensor System for Real-Time Monitoring of Toxic Environmental Volatile Organic Compounds

(2009) Francis Tsow et al.   IEEE SENSORS JOURNAL

Remote Monitoring of Implantable Cardioverter Defibrillators versus Quarterly Device Interrogations in Clinic: Results from a Randomized Pilot Clinical Trial

(2009) SANA M. AL-KHATIB et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Remote monitoring of implantable cardioverter defibrillator patients: a safe, time-saving, and cost-effective means for follow-up

(2008) M.J. P. Raatikainen et al.   EUROPACE

The Triple Aim: Care, Health, And Cost

(2008) Donald M. Berwick et al.   HEALTH AFFAIRS

Translational Research: The full cycle

(2008) Heidi Ledford   NATURE

The future of biocuration

(2008) Doug Howe et al.   NATURE

Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

(2008) Christian Gieger et al.   PLoS Genetics