Some experiences and opportunities for big data in translational research

Implementing genomic medicine in the clinic: the future is here

(2013) Teri A. Manolio et al.   GENETICS IN MEDICINE

Preparing for the 21st-Century Patient

(2013) Abhishek Pandey   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genomic Medicine, Health Information Technology, and Patient Care

(2013) Christopher G. Chute et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Inevitable Application of Big Data to Health Care

(2013) Travis B. Murdoch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Crossing the Omic Chasm

(2013) Justin Starren et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Disease-targeted sequencing: a cornerstone in the clinic

(2013) Heidi L. Rehm   NATURE REVIEWS GENETICS

Eoulsan: a cloud computing-based framework facilitating high throughput sequencing analyses

(2012) Laurent Jourdren et al.   BIOINFORMATICS

Hadoop-BAM: directly manipulating next generation sequencing data in the cloud

(2012) Matti Niemenmaa et al.   BIOINFORMATICS

A Report Template for Molecular Genetic Tests Designed to Improve Communication Between the Clinician and Laboratory

(2012) Maren T. Scheuner et al.   Genetic Testing and Molecular Biomarkers

Building a robust, scalable and standards-driven infrastructure for secondary use of EHR data: The SHARPn project

(2012) Susan Rea et al.   JOURNAL OF BIOMEDICAL INFORMATICS

The 1000 Genomes Project: data management and community access

(2012) Laura Clarke et al.   NATURE METHODS

The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies

(2011) Catherine A McCarty et al.   BMC Medical Genomics

Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality

(2011) Rebecca L. Zuvich et al.   GENETIC EPIDEMIOLOGY

Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network experience

(2011) Jyotishman Pathak et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Electronic Medical Records for Genetic Research: Results of the eMERGE Consortium

(2011) A. N. Kho et al.   Science Translational Medicine

Leveraging informatics for genetic studies: use of the electronic medical record to enable a genome-wide association study of peripheral arterial disease

(2010) Iftikhar J Kullo et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

The “Meaningful Use” Regulation for Electronic Health Records

(2010) David Blumenthal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cloud-scale RNA-sequencing differential expression analysis with Myrna

(2010) Ben Langmead et al.   GENOME BIOLOGY

CloudBurst: highly sensitive read mapping with MapReduce

(2009) M. C. Schatz   BIOINFORMATICS

The Unreasonable Effectiveness of Data

(2009) Alon Halevy et al.   IEEE INTELLIGENT SYSTEMS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Searching for SNPs with cloud computing

(2009) Ben Langmead et al.   GENOME BIOLOGY

Ordering Molecular Genetic Tests and Reporting Results

(2008) Ira M. Lubin et al.   JOURNAL OF MOLECULAR DIAGNOSTICS