Yeast synthetic biology for designed cell factories producing secretory recombinant proteins
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Yeast synthetic biology for designed cell factories producing secretory recombinant proteins
Authors
Keywords
-
Journal
FEMS YEAST RESEARCH
Volume 20, Issue 2, Pages -
Publisher
Oxford University Press (OUP)
Online
2020-01-31
DOI
10.1093/femsyr/foaa009
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Yeast Expression Systems: Overview and Recent Advances
- (2019) Roghayyeh Baghban et al. MOLECULAR BIOTECHNOLOGY
- Synthetic biology approaches for chromosomal integration of genes and pathways in industrial microbial systems
- (2019) Lei Li et al. BIOTECHNOLOGY ADVANCES
- RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae
- (2019) Guokun Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disruption of vacuolar protein sorting components of the HOPS complex leads to enhanced secretion of recombinant proteins in Pichia pastoris
- (2019) Lukas Marsalek et al. Microbial Cell Factories
- Advances in Using Hansenula polymorpha as Chassis for Recombinant Protein Production
- (2019) João Heitor Colombelli Manfrão-Netto et al. Frontiers in Bioengineering and Biotechnology
- Novel glycosylated human interferon alpha 2b expressed in glycoengineered Pichia pastoris and its biological activity: N-linked glycoengineering approach
- (2019) Srikanth Katla et al. ENZYME AND MICROBIAL TECHNOLOGY
- Improved cellulase production in recombinant Saccharomyces cerevisiae by disrupting the cell wall protein-encoding gene CWP2
- (2019) Jie Li et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Engineering the early secretory pathway for increased protein secretion in Saccharomyces cerevisiae
- (2019) Pamela B. Besada-Lombana et al. METABOLIC ENGINEERING
- Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags
- (2018) Ewelina Celińska et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Engineering strategies for enhanced production of protein and bio-products in Pichia pastoris : A review
- (2018) Zhiliang Yang et al. BIOTECHNOLOGY ADVANCES
- Structural analysis of N-/O-glycans assembled on proteins in yeasts
- (2018) Eun Jung Thak et al. JOURNAL OF MICROBIOLOGY
- Metabolic engineering of Pichia pastoris
- (2018) David A. Peña et al. METABOLIC ENGINEERING
- Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation
- (2018) Chiu-Ping Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysosomal Targeting Enhancement by Conjugation of Glycopeptides Containing Mannose-6-phosphate Glycans Derived from Glyco-engineered Yeast
- (2018) Ji-Yeon Kang et al. Scientific Reports
- Mutational Mtc6p attenuates autophagy and improves secretory expression of heterologous proteins in Kluyveromyces marxianus
- (2018) Yang Liu et al. Microbial Cell Factories
- Engineering the protein secretory pathway of Saccharomyces cerevisiae enables improved protein production
- (2018) Mingtao Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of recombinant Yarrowia lipolytica producing virus-like particles of a fish nervous necrosis virus
- (2017) Van-Trinh Luu et al. JOURNAL OF MICROBIOLOGY
- Synonymous Codons: Choose Wisely for Expression
- (2017) Christina E. Brule et al. TRENDS IN GENETICS
- Efficient protein production by yeast requires global tuning of metabolism
- (2017) Mingtao Huang et al. Nature Communications
- A Modular Toolkit for Generating Pichia pastoris Secretion Libraries
- (2017) Ulrike Obst et al. ACS Synthetic Biology
- Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris
- (2017) Lukas Marsalek et al. Biotechnology Journal
- Systematic Optimization of Protein Secretory Pathways in Saccharomyces cerevisiae to Increase Expression of Hepatitis B Small Antigen
- (2017) Jiayuan Sheng et al. Frontiers in Microbiology
- Cell Factory Engineering
- (2017) Anne Mathilde Davy et al. Cell Systems
- Codon optimization of Saccharomyces cerevisiae mating factor alpha prepro-leader to improve recombinant protein production in Pichia pastoris
- (2016) Jungoh Ahn et al. BIOTECHNOLOGY LETTERS
- Synthetic biology and molecular genetics in non-conventional yeasts: Current tools and future advances
- (2016) James M. Wagner et al. FUNGAL GENETICS AND BIOLOGY
- A dual approach for improving homogeneity of a human-type N-glycan structure in Saccharomyces cerevisiae
- (2016) Mari A. Piirainen et al. GLYCOCONJUGATE JOURNAL
- A new set of rDNA-NTS-based multiple integrative cassettes for the development of antibiotic-marker-free recombinant yeasts
- (2016) Hye Yun Moon et al. JOURNAL OF BIOTECHNOLOGY
- Endogenous signal peptides in recombinant protein production by Pichia pastoris: From in-silico analysis to fermentation
- (2016) Aslan Massahi et al. JOURNAL OF THEORETICAL BIOLOGY
- A highly efficient single-step, markerless strategy for multi-copy chromosomal integration of large biochemical pathways in Saccharomyces cerevisiae
- (2016) Shuobo Shi et al. METABOLIC ENGINEERING
- Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum
- (2016) Jorg C. de Ruijter et al. Microbial Cell Factories
- N-hypermannose glycosylation disruption enhances recombinant protein production by regulating secretory pathway and cell wall integrity in Saccharomyces cerevisiae
- (2016) Hongting Tang et al. Scientific Reports
- Modular Integrated Secretory System Engineering in Pichia pastoris To Enhance G-Protein Coupled Receptor Expression
- (2016) Katrien Claes et al. ACS Synthetic Biology
- Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica
- (2016) Cory Schwartz et al. ACS Synthetic Biology
- The Genomic Landscape of Position Effects on Protein Expression Level and Noise in Yeast
- (2016) Xiaoshu Chen et al. Cell Systems
- Hansenula polymorpha Hac1p Is Critical to ProteinN-Glycosylation Activity Modulation, as Revealed by Functional and Transcriptomic Analyses
- (2015) Hye-Yun Moon et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Analysis of antibody production in Saccharomyces cerevisiae: effects of ER protein quality control disruption
- (2015) Jorg C. de Ruijter et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Overexpression of native Saccharomyces cerevisiae ER-to-Golgi SNARE genes increased heterologous cellulase secretion
- (2015) John Henry D. Van Zyl et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Engineering protein folding and translocation improves heterologous protein secretion inSaccharomyces cerevisiae
- (2015) Hongting Tang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Genome-scale metabolic model ofPichia pastoriswith native and humanized glycosylation of recombinant proteins
- (2015) Zahra Azimzadeh Irani et al. BIOTECHNOLOGY AND BIOENGINEERING
- Characterization of Aspergillus niger endo-1,4-β-glucanase ENG1 secreted from Saccharomyces cerevisiae using different expression vectors
- (2015) S.M. Taipakova et al. GENETICS AND MOLECULAR RESEARCH
- Increased mannosylphosphorylation of N-glycans by heterologous expression of YlMPO1 in glyco-engineered Saccharomyces cerevisiae for mannose-6-phosphate modification
- (2015) Jin Young Gil et al. JOURNAL OF BIOTECHNOLOGY
- Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast
- (2015) Mingtao Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Efficient Genome-Wide Fusion Partner Screening System for Secretion of Recombinant Proteins in Yeast
- (2015) Jung-Hoon Bae et al. Scientific Reports
- Gene and Protein Sequence Optimization for High-Level Production of Fully Active and Aglycosylated Lysostaphin in Pichia pastoris
- (2014) H. Zhao et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- A condition-specific codon optimization approach for improved heterologous gene expression in Saccharomyces cerevisiae
- (2014) Amanda M Lanza et al. BMC Systems Biology
- Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production
- (2014) Justyna Nocon et al. METABOLIC ENGINEERING
- Glycoengineering of yeasts from the perspective of glycosylation efficiency
- (2014) Mari A. Piirainen et al. New Biotechnology
- The Effects of Codon Context on In Vivo Translation Speed
- (2014) Fabienne F. V. Chevance et al. PLoS Genetics
- Enhancement of lipase r27RCL production in Pichia pastoris by regulating gene dosage and co-expression with chaperone protein disulfide isomerase
- (2013) Chong Sha et al. ENZYME AND MICROBIAL TECHNOLOGY
- The effect of α-mating factor secretion signal mutations on recombinant protein expression in Pichia pastoris
- (2013) Geoff P. Lin-Cereghino et al. GENE
- Production of sialylated O-linked glycans in Pichia pastoris
- (2013) S. R. Hamilton et al. GLYCOBIOLOGY
- Metabolic reaction network ofPichia pastoriswith glycosylation reactions: Flux analysis for erythropoietin production
- (2013) Melda Ş. Eskitoros et al. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
- Can too many copies spoil the broth?
- (2013) Rochelle Aw et al. Microbial Cell Factories
- A Combined System for Engineering Glycosylation Efficiency and Glycan Structure in Saccharomyces cerevisiae
- (2012) Farnoush Parsaie Nasab et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Improvement of N-glycan site occupancy of therapeutic glycoproteins produced in Pichia pastoris
- (2012) Byung-Kwon Choi et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Computational codon optimization of synthetic gene for protein expression
- (2012) Bevan Chung et al. BMC Systems Biology
- Architecture and Biosynthesis of the Saccharomyces cerevisiae Cell Wall
- (2012) P. Orlean GENETICS
- Remodeling of the glycosylation pathway in the methylotrophic yeast Hansenula polymorpha to produce human hybrid-type N-glycans
- (2012) Seon Ah Cheon et al. JOURNAL OF MICROBIOLOGY
- Engineering the yeast Yarrowia lipolytica for the production of therapeutic proteins homogeneously glycosylated with Man8GlcNAc2 and Man5GlcNAc2
- (2012) Karen De Pourcq et al. Microbial Cell Factories
- A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes
- (2012) Petra Tiels et al. NATURE BIOTECHNOLOGY
- Systematic Single-Cell Analysis of Pichia pastoris Reveals Secretory Capacity Limits Productivity
- (2012) Kerry Routenberg Love et al. PLoS One
- Engineering Yarrowia lipolytica to Produce Glycoproteins Homogeneously Modified with the Universal Man3GlcNAc2 N-Glycan Core
- (2012) Karen De Pourcq et al. PLoS One
- Expression of glycoproteins bearing complex human-like glycans with galactose terminal in Hansenula polymorpha
- (2012) Hui Wang et al. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
- Production of recombinant proteins by yeast cells
- (2011) Eda Çelik et al. BIOTECHNOLOGY ADVANCES
- Elimination of -mannose glycan structures in Pichia pastoris
- (2011) D. Hopkins et al. GLYCOBIOLOGY
- Native-State Stability Determines the Extent of Degradation Relative to Secretion of Protein Variants from Pichia pastoris
- (2011) Graham Whyteside et al. PLoS One
- Essential Role of YlMPO1, a NovelYarrowia lipolyticaHomologue ofSaccharomyces cerevisiae MNN4, in Mannosylphosphorylation of N- and O-Linked Glycans
- (2010) Jeong-Nam Park et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Engineering of glycosylation in yeast and other fungi: current state and perspectives
- (2010) Karen De Pourcq et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Post-translational modifications of protein biopharmaceuticals
- (2010) Gary Walsh DRUG DISCOVERY TODAY
- Conditional cell-wall mutants of Saccharomyces cerevisiae as delivery vehicles for therapeutic agents in vivo to the GI tract
- (2010) Walid A.M. Omara et al. JOURNAL OF BIOTECHNOLOGY
- The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins
- (2010) Mouna Guerfal et al. Microbial Cell Factories
- Disruption of the OCH1 and MNN1 genes decrease N-glycosylation on glycoprotein expressed in Kluyveromyces lactis
- (2009) Bo Liu et al. JOURNAL OF BIOTECHNOLOGY
- Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response
- (2009) Sebastian Schuck et al. JOURNAL OF CELL BIOLOGY
- Transcript-specific translational regulation in the unfolded protein response ofSaccharomyces cerevisiae
- (2008) Tom Payne et al. FEBS LETTERS
- Engineering of a mammalian O-glycosylation pathway in the yeast Saccharomyces cerevisiae: production of O-fucosylated epidermal growth factor domains
- (2008) Y. Chigira et al. GLYCOBIOLOGY
- Engineering of mucin-type human glycoproteins in yeast cells
- (2008) K. Amano et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More