A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes

Engineering the yeast Yarrowia lipolytica for the production of therapeutic proteins homogeneously glycosylated with Man8GlcNAc2 and Man5GlcNAc2

(2012) Karen De Pourcq et al.   Microbial Cell Factories

Sequencing of high G+C microbial genomes using the ultrafast pyrosequencing technology

(2011) Patrick Schwientek et al.   JOURNAL OF BIOTECHNOLOGY

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont

(2010) Yanping Zhu et al.   Nature Chemical Biology

Decision-making in structure solution using Bayesian estimates of map quality: thePHENIX AutoSolwizard

(2009) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Glycosylation- and phosphorylation-dependent intracellular transport of lysosomal hydrolases

(2009) Sandra Pohl et al.   BIOLOGICAL CHEMISTRY

Production of human  -hexosaminidase A with highly phosphorylated N-glycans by the overexpression of the Ogataea minuta MNN4 gene

(2009) H. Akeboshi et al.   GLYCOBIOLOGY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Glycoengineered Acid α-Glucosidase With Improved Efficacy at Correcting the Metabolic Aberrations and Motor Function Deficits in a Mouse Model of Pompe Disease

(2009) Yunxiang Zhu et al.   MOLECULAR THERAPY