KLF15-activating Twist2 ameliorated hepatic steatosis by inhibiting inflammation and improving mitochondrial dysfunction via NF-κB–FGF21 or SREBP1c-FGF21 pathway

Endoplasmic Reticulum Stress in Metabolic Liver Diseases and Hepatic Fibrosis

(2019) Jessica Maiers et al.   SEMINARS IN LIVER DISEASE

From NASH to HCC: current concepts and future challenges

(2019) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism

(2019) Masaji Sakaguchi et al.   Nature Communications

FTO promotes SREBP1c maturation and enhances CIDEC transcription during lipid accumulation in HepG2 cells

(2018) Ao Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases

(2018) Varman T. Samuel et al.   Cell Metabolism

Endoplasmic Reticulum stress signaling and the pathogenesis of Non-Alcoholic Fatty Liver Disease

(2018) Cynthia Lebeaupin et al.   JOURNAL OF HEPATOLOGY

The Krüppel-Like Factors and Control of Energy Homeostasis

(2018) Paishiun N Hsieh et al.   ENDOCRINE REVIEWS

Fatty liver and FGF21 physiology

(2017) Eleftheria Maratos-Flier   EXPERIMENTAL CELL RESEARCH

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis

(2016) Lucas D. BonDurant et al.   Annual Review of Nutrition

Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum

(2016) Timothy Hardy et al.   Annual Review of Pathology-Mechanisms of Disease

Understanding the Physiology of FGF21

(2016) Ffolliott Martin Fisher et al.   Annual Review of Physiology

Innate Immunity and Inflammation in NAFLD/NASH

(2016) Marco Arrese et al.   DIGESTIVE DISEASES AND SCIENCES

A possible regulatory link between Twist 1 and PPARγ gene regulation in 3T3-L1 adipocytes

(2016) Rui Ren et al.   Lipids in Health and Disease

Mechanism of ER Stress and Inflammation for Hepatic Insulin Resistance in Obesity

(2015) Ok-Kyung Kim et al.   ANNALS OF NUTRITION AND METABOLISM

p18, a novel adaptor protein, regulates pulmonary endothelial barrier function via enhanced endocytic recycling of VE-cadherin

(2015) Havovi Chichger et al.   FASEB JOURNAL

The role of fibroblast growth factor 21 in the pathogenesis of non-alcoholic fatty liver disease and implications for therapy

(2015) Jia Liu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

FoxO1: mute for a tuned metabolism?

(2015) Zhiyong Cheng   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hepatic Steatosis as a Marker of Metabolic Dysfunction

(2015) Elisa Fabbrini et al.   Nutrients

From NAFLD to NASH to cirrhosis—new insights into disease mechanisms

(2013) Alexander Wree et al.   Nature Reviews Gastroenterology & Hepatology

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

Manganese superoxide dismutase regulation and cancer

(2012) Sanjit Kumar Dhar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase C/protein kinase G/p65/PPAR gamma coactivator 1 alpha pathway

(2012) Lei Zhou et al.   HEPATOLOGY

Protein Antigen Adsorption to the DDA/TDB Liposomal Adjuvant: Effect on Protein Structure, Stability, and Liposome Physicochemical Characteristics

(2012) Mette Hamborg et al.   PHARMACEUTICAL RESEARCH

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

The role of oxidative stress in non-alcoholic steatohepatitis

(2011) G.H. Koek et al.   CLINICA CHIMICA ACTA

The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes

(2011) Y. Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Redundant or separate entities?--roles of Twist1 and Twist2 as molecular switches during gene transcription

(2010) H. L. Franco et al.   NUCLEIC ACIDS RESEARCH

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Twist-1 Is a PPARδ-Inducible, Negative-Feedback Regulator of PGC-1α in Brown Fat Metabolism

(2009) Dongning Pan et al.   CELL

A Possible Inflammatory Role of Twist1 in Human White Adipocytes

(2009) A. T. Pettersson et al.   DIABETES

A twist of insight - the role of Twist-family bHLH factors in development

(2009) Ralston M. Barnes et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man

(2008) Cecilia Gälman et al.   Cell Metabolism

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES