Deficiency in the short-chain acyl-CoA dehydrogenase protects mice against diet-induced obesity and insulin resistance

Adipogenesis and metabolic health

(2019) Alexandra L. Ghaben et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unraveling the Regulation of Hepatic Gluconeogenesis

(2019) Xueping Zhang et al.   Frontiers in Endocrinology

Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt ActivationNovelty and Significance

(2018) Xukun Bi et al.   CIRCULATION RESEARCH

Regulation of hepatic gluconeogenesis by nuclear factor Y transcription factor in mice

(2018) Yanjie Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinoic acid receptor-related orphan receptor α stimulates adipose tissue inflammation by modulating endoplasmic reticulum stress

(2017) Yin Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance

(2017) Max C. Petersen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

New anti-cancer molecules targeting HSPA5/BIP to induce endoplasmic reticulum stress, autophagy and apoptosis

(2016) Michaël Cerezo et al.   Autophagy

Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance

(2016) Max C. Petersen et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity-induced endoplasmic reticulum stress suppresses nuclear factor-Y expression

(2016) Yulan Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue

(2016) Sun-Joong Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver

(2016) Sujoy Ghosh et al.   Nutrition & Metabolism

N-acetylcysteine inhibits lipid accumulation in mouse embryonic adipocytes

(2016) A. Pieralisi et al.   Redox Biology

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

(2015) Gijs den Besten et al.   DIABETES

De novo lipogenesis in health and disease

(2014) Fatima Ameer et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Short-Chain Fatty Acids Activate AMP-Activated Protein Kinase and Ameliorate Ethanol-Induced Intestinal Barrier Dysfunction in Caco-2 Cell Monolayers

(2013) Elhaseen E. Elamin et al.   JOURNAL OF NUTRITION

Cancer Cells Resistant to Therapy Promote Cell Surface Relocalization of GRP78 Which Complexes with PI3K and Enhances PI(3,4,5)P3 Production

(2013) Yi Zhang et al.   PLoS One

Diacylglycerol Activation of Protein Kinase Cε and Hepatic Insulin Resistance

(2012) François R. Jornayvaz et al.   Cell Metabolism

Intrahepatic Diacylglycerol Content Is Associated With Hepatic Insulin Resistance in Obese Subjects

(2012) Faidon Magkos et al.   GASTROENTEROLOGY

Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity

(2012) Y Li et al.   INTERNATIONAL JOURNAL OF OBESITY

Malonyl-CoA: the regulator of fatty acid synthesis and oxidation

(2012) Daniel W. Foster   JOURNAL OF CLINICAL INVESTIGATION

Measurement of tissue acyl-CoAs using flow-injection tandem mass spectrometry: acyl-CoA profiles in short-chain fatty acid oxidation defects

(2012) Andrew A. Palladino et al.   MOLECULAR GENETICS AND METABOLISM

Brain Transcriptional Responses to High-Fat Diet in Acads-Deficient Mice Reveal Energy Sensing Pathways

(2012) Claudia Kruger et al.   PLoS One

Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling

(2011) S. Wey et al.   BLOOD

The minor C-allele of rs2014355 in ACADSis associated with reduced insulin release following an oral glucose load

(2011) Malene Hornbak et al.   BMC Medical Genetics

Characterization of murine melanocortin receptors mediating adipocyte lipolysis and examination of signalling pathways involved

(2011) Cathrine Laustrup Møller et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

(2011) N. Kumashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance to High-Fat Diet-Induced Obesity and Insulin Resistance in Mice with Very Long-Chain Acyl-CoA Dehydrogenase Deficiency

(2010) Dongyan Zhang et al.   Cell Metabolism

The critical role of GRP78 in physiologic and pathologic stress

(2010) Kyle T Pfaffenbach et al.   CURRENT OPINION IN CELL BIOLOGY

Molecular pathogenesis of a novel mutation, G108D, in short-chain acyl-CoA dehydrogenase identified in subjects with short-chain acyl-CoA dehydrogenase deficiency

(2010) Kenichiro Shirao et al.   HUMAN GENETICS

Untangling HDL quantitative trait loci on mouse chromosome 5 and identifyingScarb1andAcadsas the underlying genes

(2010) Zhiguang Su et al.   JOURNAL OF LIPID RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways

(2009) J A Kelber et al.   ONCOGENE

Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium

(2008) Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA