Cobalt nanoparticles trigger ferroptosis‐like cell death (oxytosis) in neuronal cells: Potential implications for neurodegenerative disease

INSIdE NANO: a systems biology framework to contextualize the mechanism-of-action of engineered nanomaterials

(2019) Angela Serra et al.   Scientific Reports

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity

(2019) Jennifer Yinuo Cao et al.   Cell Reports

Comparison of the neurotoxicity associated with cobalt nanoparticles and cobalt chloride in Wistar rats

(2019) Fuli Zheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Calcium-dependent cyto- and genotoxicity of nickel metal and nickel oxide nanoparticles in human lung cells

(2018) Sebastiano Di Bucchianico et al.   Particle and Fibre Toxicology

Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System

(2018) Jan Lewerenz et al.   Frontiers in Neuroscience

Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

(2018) Moataz Abdalkader et al.   Frontiers in Neuroscience

Live and Let Die? Life Cycle Human Health Impacts from the Use of Tire Studs

(2018) Anna Furberg et al.   International Journal of Environmental Research and Public Health

Nanoparticles of WC-Co, WC, Co and Cu of relevance for traffic wear particles – Particle stability and reactivity in synthetic surface water and influence of humic matter

(2017) Yolanda S. Hedberg et al.   ENVIRONMENTAL POLLUTION

Cobalt toxicity in humans—A review of the potential sources and systemic health effects

(2017) Laura Leyssens et al.   TOXICOLOGY

BID links ferroptosis to mitochondrial cell death pathways

(2017) Sandra Neitemeier et al.   Redox Biology

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

(2017) Omkar Zilka et al.   ACS Central Science

Importance of the HIF pathway in cobalt nanoparticle-induced cytotoxicity and inflammation in human macrophages

(2015) Agata Nyga et al.   Nanotoxicology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Molecular analysis of chromium and cobalt-related toxicity

(2014) Brian Scharf et al.   Scientific Reports

A review of the health hazards posed by cobalt

(2013) Dennis J. Paustenbach et al.   CRITICAL REVIEWS IN TOXICOLOGY

Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

(2013) Joanna A. Korecka et al.   PLoS One

NanoMiner — Integrative Human Transcriptomics Data Resource for Nanoparticle Research

(2013) Lingjia Kong et al.   PLoS One

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Cobalt and Chromium Measurement in Patients with Metal Hip Prostheses

(2012) M. P. Estey et al.   CLINICAL CHEMISTRY

Neurotoxicity of cobalt

(2011) S Catalani et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Nrf2 promotes neuronal cell differentiation

(2009) Fei Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of sight and sound. Could it be the hip?

(2009) Maria Cristina Rizzetti et al.   LANCET

Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

(2009) Yanping Li et al.   NATURE NEUROSCIENCE

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

A Systematic Comparison of the Actual, Potential, and Theoretical Health Effects of Cobalt and Chromium Exposures from Industry and Surgical Implants

(2008) Gemma M. Keegan et al.   CRITICAL REVIEWS IN TOXICOLOGY

Toxicity of Tungsten Carbide and Cobalt-Doped Tungsten Carbide Nanoparticles in Mammalian Cells in Vitro

(2008) Susanne Bastian et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The oxidation of glutathione by cobalt/tungsten carbide contributes to hard metal-induced oxidative stress

(2008) Ivana Fenoglio et al.   FREE RADICAL RESEARCH