Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats

Umbelliferone Ameliorates CCl4-Induced Liver Fibrosis in Rats by Upregulating PPARγ and Attenuating Oxidative Stress, Inflammation, and TGF-β1/Smad3 Signaling

(2019) Ayman M. Mahmoud et al.   INFLAMMATION

Chicoric acid prevents methotrexate-induced kidney injury by suppressing NF-κB/NLRP3 inflammasome activation and up-regulating Nrf2/ARE/HO-1 signaling

(2019) Sanaa M. Abd El-Twab et al.   INFLAMMATION RESEARCH

Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation, and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity

(2019) Aladaileh et al.   Biomolecules

Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats

(2019) Saleem H. Aladaileh et al.   Antioxidants

Ellagic acid as a potential antioxidant, alleviates methotrexate-induced hepatotoxicity in male rats

(2018) Saeed Mehrzadi et al.   ACTA CHIRURGICA BELGICA

Commiphora molmol protects against methotrexate-induced nephrotoxicity by up-regulating Nrf2/ARE/HO-1 signaling

(2018) Ayman M. Mahmoud et al.   BIOMEDICINE & PHARMACOTHERAPY

An in vitro inflammation model to study the Nrf2 and NF-κB crosstalk in presence of ferulic acid as modulator

(2018) Nadia Lampiasi et al.   IMMUNOBIOLOGY

Health-related effects and improving extractability of cereal arabinoxylans

(2018) Abdulmannan Fadel et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Spirulina ameliorates methotrexate hepatotoxicity via antioxidant, immune stimulation, and proinflammatory cytokines and apoptotic proteins modulation

(2018) Asmaa F. Khafaga et al.   LIFE SCIENCES

Mitochondrial dysfunction and oxidative stress are involved in the mechanism of methotrexate-induced renal injury and electrolytes imbalance

(2018) Reza Heidari et al.   BIOMEDICINE & PHARMACOTHERAPY

Ferulic acid (FA) abrogates γ-radiation induced oxidative stress and DNA damage by up-regulating nuclear translocation of Nrf2 and activation of NHEJ pathway

(2017) Ujjal Das et al.   FREE RADICAL RESEARCH

Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells

(2017) Cristina Perez-Ternero et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Ferulic acid exhibits antiepileptogenic effect and prevents oxidative stress and cognitive impairment in the kindling model of epilepsy

(2017) Parichehr Hassanzadeh et al.   LIFE SCIENCES

The Role of Nrf2 in Cardiovascular Function and Disease

(2017) Sandro Satta et al.   Oxidative Medicine and Cellular Longevity

The Effects of Ferulic Acid Against Oxidative Stress and Inflammation in Formaldehyde-Induced Hepatotoxicity

(2016) Fethullah Gerin et al.   INFLAMMATION

Ferulic acid prevents liver injury induced by Diosbulbin B and its mechanism

(2016) Chengwei Niu et al.   BioScience Trends

Rutin ameliorates methotrexate induced hepatic injury in rats

(2015) Esra Erdogan et al.   Acta Cirurgica Brasileira

The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in metabolism, immunity, and cancer

(2015) Jung-Hoon Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation

(2015) Ayman M. Mahmoud et al.   Genes and Nutrition

Ferulic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NADPH oxidase and NF-κB pathway

(2015) Yan-jun Cao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats

(2015) Azza A. K. El-Sheikh et al.   MEDIATORS OF INFLAMMATION

Ferulic Acid Protects Against Lead Acetate-Induced Inhibition of Neurite Outgrowth by Upregulating HO-1 in PC12 Cells: Involvement of ERK1/2-Nrf2 Pathway

(2015) Chun-Lei Yu et al.   MOLECULAR NEUROBIOLOGY

18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation

(2015) Ayman M. Mahmoud et al.   Genes and Nutrition

Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis

(2013) VK Kolli et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Ferulic Acid Modulates Fluoride-Induced Oxidative Hepatotoxicity in Male Wistar Rats

(2012) Lakshmikanthan Panneerselvam et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Methotrexate: a detailed review on drug delivery and clinical aspects

(2012) Zulfequar Ahamad Khan et al.   Expert Opinion on Drug Delivery

The Absence of Nrf2 Enhances NF-B-Dependent Inflammation following Scratch Injury in Mouse Primary Cultured Astrocytes

(2012) Hao Pan et al.   MEDIATORS OF INFLAMMATION

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

PPARγ inhibits NF-κB-dependent transcriptional activation in skeletal muscle

(2009) A. H. V. Remels et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Neutrophil Infiltration and Oxidative Stress May Play a Critical Role in Methotrexate-Induced Renal Damage

(2009) Viswa Kalyan Kolli et al.   CHEMOTHERAPY

The future of drug safety testing: expanding the view and narrowing the focus

(2009) James L. Stevens et al.   DRUG DISCOVERY TODAY