Inhibition of FGFR Signaling Partially Rescues Osteoarthritis in Mice Overexpressing High Molecular Weight FGF2 Isoforms

Wnt signaling: a promising target for osteoarthritis therapy

(2019) Yudan Wang et al.   Cell Communication and Signaling

Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection

(2018) Patience M. Burt et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study

(2017) Lucia Nogova et al.   JOURNAL OF CLINICAL ONCOLOGY

Fibroblast Growth Factor Receptor 3 Inhibits Osteoarthritis Progression in the Knee Joints of Adult Mice

(2016) Junzhou Tang et al.   Arthritis & Rheumatology

Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage

(2015) Marcela Buchtova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes

(2015) Leilei Zhong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms of fibroblast growth factor signaling in the ovarian follicle

(2015) Christopher A Price   JOURNAL OF ENDOCRINOLOGY

Osteocyte-Specific Deletion of Fgfr1 Suppresses FGF23

(2014) Zhousheng Xiao et al.   PLoS One

Low-density lipoprotein receptor–related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction

(2014) Youngnim Shin et al.   ARTHRITIS RESEARCH & THERAPY

Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice

(2012) Hwanhee Oh et al.   ARTHRITIS AND RHEUMATISM

Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice

(2012) Tujun Weng et al.   ARTHRITIS AND RHEUMATISM

Pharmacological inhibition of fibroblast growth factor (FGF) receptor signaling ameliorates FGF23-mediated hypophosphatemic rickets

(2012) Simon Wöhrle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family

(2012) Xin Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fibroblast growth factor control of cartilage homeostasis

(2012) M.B. Ellman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

An Atypical Degenerative Osteoarthropathy in Hyp Mice is Characterized by a Loss in the Mineralized Zone of Articular Cartilage

(2011) Guoying Liang et al.   CALCIFIED TISSUE INTERNATIONAL

Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis

(2011) B.Y. Chan et al.   OSTEOARTHRITIS AND CARTILAGE

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

(2011) Dongyao Yan et al.   ARTHRITIS RESEARCH & THERAPY

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis

(2009) Shi-Lu Chia et al.   ARTHRITIS AND RHEUMATISM

Survey of the Enthesopathy of X-Linked Hypophosphatemia and Its Characterization in Hyp Mice

(2009) Guoying Liang et al.   CALCIFIED TISSUE INTERNATIONAL

Nuclear Isoforms of Fibroblast Growth Factor 2 Are Novel Inducers of Hypophosphatemia via Modulation of FGF23 and KLOTHO

(2009) Liping Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene targeted ablation of high molecular weight fibroblast growth factor-2

(2008) Mohamad Azhar et al.   DEVELOPMENTAL DYNAMICS

Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes

(2007) Hee-Jeong Im et al.   JOURNAL OF CELLULAR PHYSIOLOGY