Low-density lipoprotein receptor–related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction
Published 2014 View Full Article
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Title
Low-density lipoprotein receptor–related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction
Authors
Keywords
Cartilage Destruction, Chondrocyte Apoptosis, International Cartilage Repair Society, Micromass Culture, Catabolic Factor
Journal
ARTHRITIS RESEARCH & THERAPY
Volume 16, Issue 1, Pages R37
Publisher
Springer Nature
Online
2014-01-31
DOI
10.1186/ar4466
References
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Related references
Note: Only part of the references are listed.- Heterozygosity for an inactivating mutation in low-density lipoprotein-related receptor 6 (Lrp6) increases osteoarthritis severity in mice after ligament and meniscus injury
- (2013) D.M. Joiner et al. OSTEOARTHRITIS AND CARTILAGE
- Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition
- (2013) Ryan C. Riddle et al. PLoS One
- Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice
- (2012) Hwanhee Oh et al. ARTHRITIS AND RHEUMATISM
- Genetic deletion of low-density lipoprotein receptor-related protein 5 increases cartilage degradation in instability-induced osteoarthritis
- (2012) L. Lodewyckx et al. RHEUMATOLOGY
- Bone morphogenetic protein-2-induced Wnt/beta-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes
- (2012) Ioanna Papathanasiou et al. ARTHRITIS RESEARCH & THERAPY
- Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction
- (2011) J-H Ryu et al. CELL DEATH AND DIFFERENTIATION
- To Seek Shelter from the Wnt in Osteoarthritis? Wnt-Signaling as a Target for Osteoarthritis Therapy
- (2010) Arjen B. Blom et al. CURRENT DRUG TARGETS
- Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction
- (2010) Siyoung Yang et al. NATURE MEDICINE
- Matrix metalloproteinase 13âdeficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
- (2009) C. B. Little et al. ARTHRITIS AND RHEUMATISM
- Esophageal cancer related gene 4 (ECRG4) is a marker of articular chondrocyte differentiation and cartilage destruction
- (2009) Yun Hyun Huh et al. GENE
- Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction
- (2008) Mei Zhu et al. ARTHRITIS AND RHEUMATISM
- Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum
- (2008) Vijay K. Yadav et al. CELL
- Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice
- (2008) Mei Zhu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Molecular network of cartilage homeostasis and osteoarthritis
- (2007) Megumi Hashimoto et al. MEDICINAL RESEARCH REVIEWS
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