Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation

FAP57/WDR65 targets assembly of a subset of inner arm dyneins and connects to regulatory hubs in cilia

(2019) Jianfeng Lin et al.   MOLECULAR BIOLOGY OF THE CELL

Shedding light on the role of cAMP in mammalian sperm physiology

(2018) Melanie Balbach et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Asymmetric distribution and spatial switching of dynein activity generates ciliary motility

(2018) Jianfeng Lin et al.   SCIENCE

Genetically Encoded FRET Biosensors to Illuminate Compartmentalised GPCR Signalling

(2018) Michelle L. Halls et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding

(2018) F. Windler et al.   Nature Communications

TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells

(2018) Bifeng Pan et al.   NEURON

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Protein abundance of AKT and ERK pathway components governs cell type‐specific regulation of proliferation

(2017) Lorenz Adlung et al.   Molecular Systems Biology

Signaling in Sperm: More Different than Similar

(2017) U.B. Kaupp et al.   TRENDS IN CELL BIOLOGY

Sperm Sensory Signaling

(2017) Dagmar Wachten et al.   Cold Spring Harbor Perspectives in Biology

CatSperζ regulates the structural continuity of sperm Ca2+ signaling domains and is required for normal fertility

(2017) Jean-Ju Chung et al.   eLife

Network model predicts that CatSper is the main Ca2+ channel in the regulation of sea urchin sperm motility

(2017) Jesús Espinal-Enríquez et al.   Scientific Reports

Cation dependencies and turnover rates of the human K+-dependent Na+-Ca2+ exchangers NCKX1, NCKX2, NCKX3 and NCKX4

(2016) Ali H. Jalloul et al.   CELL CALCIUM

Sperm as microswimmers – navigation and sensing at the physical limit

(2016) Ulrich B. Kaupp et al.   European Physical Journal-Special Topics

Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics

(2016) Bryn S. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel biosensor to study cAMP dynamics in cilia and flagella

(2016) Shatanik Mukherjee et al.   eLife

Parallel Allostery by cAMP and PDE Coordinates Activation and Termination Phases in cAMP Signaling

(2015) Srinath Krishnamurthy et al.   BIOPHYSICAL JOURNAL

The elusive mechanotransduction machinery of hair cells

(2015) Bo Zhao et al.   CURRENT OPINION IN NEUROBIOLOGY

Proteomics of Primary Cilia by Proximity Labeling

(2015) David U. Mick et al.   DEVELOPMENTAL CELL

cGMP in mouse rods: the spatiotemporal dynamics underlying single photon responses

(2015) Owen P. Gross et al.   Frontiers in Molecular Neuroscience

Soluble adenylyl cyclase of sea urchin spermatozoa

(2014) Victor D. Vacquier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Active Site Coupling in PDE:PKA Complexes Promotes Resetting of Mammalian cAMP Signaling

(2014) Srinath Krishnamurthy et al.   BIOPHYSICAL JOURNAL

The CatSper channel controls chemosensation in sea urchin sperm

(2014) R. Seifert et al.   EMBO JOURNAL

High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor

(2014) Magdalena Pichlo et al.   JOURNAL OF CELL BIOLOGY

G-protein-coupled receptors, Hedgehog signaling and primary cilia

(2014) Saikat Mukhopadhyay et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Kinetics of Ligand-Receptor Interaction Reveals an Induced-Fit Mode of Binding in a Cyclic Nucleotide-Activated Protein

(2013) Sebastian Peuker et al.   BIOPHYSICAL JOURNAL

An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier

(2013) David K. Breslow et al.   JOURNAL OF CELL BIOLOGY

Niflumic acid disrupts marine spermatozoan chemotaxis without impairing the spatiotemporal detection of chemoattractant gradients

(2013) A. Guerrero et al.   JOURNAL OF CELL SCIENCE

Simultaneous knockout ofSlo3andCatSper1abolishes all alkalization- and voltage-activated current in mouse spermatozoa

(2013) Xu-Hui Zeng et al.   JOURNAL OF GENERAL PHYSIOLOGY

The SLC24 gene family of Na+/Ca2+–K+ exchangers: From sight and smell to memory consolidation and skin pigmentation

(2013) Paul P.M. Schnetkamp   MOLECULAR ASPECTS OF MEDICINE

Direct recording and molecular identification of the calcium channel of primary cilia

(2013) Paul G. DeCaen et al.   NATURE

Primary cilia are specialized calcium signalling organelles

(2013) Markus Delling et al.   NATURE

Conserved structural motifs in the central pair complex of eukaryotic flagella

(2012) Blanca I. Carbajal-González et al.   Cytoskeleton

The rate of change in Ca2+concentration controls sperm chemotaxis

(2012) Luis Alvarez et al.   JOURNAL OF CELL BIOLOGY

A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia

(2012) Hooi Lynn Kee et al.   NATURE CELL BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Optically monitoring voltage in neurons by photo-induced electron transfer through molecular wires

(2012) E. W. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The use of selected reaction monitoring in quantitative proteomics

(2012) Stephen W Holman et al.   Bioanalysis

Mechanism Regulating Ca2+-dependent Mechanosensory Behaviour in Sea Urchin Spermatozoa

(2011) Yuka Kambara et al.   CELL STRUCTURE AND FUNCTION

Exploring HCN channels as novel drug targets

(2011) Otilia Postea et al.   NATURE REVIEWS DRUG DISCOVERY

Mammalian Cyclic Nucleotide Phosphodiesterases: Molecular Mechanisms and Physiological Functions

(2011) Sharron H. Francis et al.   PHYSIOLOGICAL REVIEWS

Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy

(2011) Philip Brownridge et al.   PROTEOMICS

Activation of Visual Pigments by Light and Heat

(2011) D.-G. Luo et al.   SCIENCE

A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa

(2011) Jean-Ju Chung et al.   Nature Communications

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

A Novel, Single, Transmembrane Protein CATSPERG Is Associated with CATSPER1 Channel Protein1

(2009) Haikun Wang et al.   BIOLOGY OF REPRODUCTION

Phototransduction Motifs and Variations

(2009) King-Wai Yau et al.   CELL

Low-Conductance HCN1 Ion Channels Augment the Frequency Response of Rod and Cone Photoreceptors

(2009) A. J. Barrow et al.   JOURNAL OF NEUROSCIENCE

An Atypical CNG Channel Activated by a Single cGMP Molecule Controls Sperm Chemotaxis

(2009) W. Bonigk et al.   Science Signaling

Ion channels that control fertility in mammalian spermatozoa

(2008) Betsy Navarro et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Accuracy of direct gradient sensing by single cells

(2008) R. G. Endres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA