Irisin increases the expression of anorexigenic and neurotrophic genes in mouse brain

A role for FNDC5/Irisin in the beneficial effects of exercise on the brain and in neurodegenerative diseases

(2019) Michael F. Young et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor?

(2019) Athanasios D. Anastasilakis et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal PGC-1α/FNDC5/BDNF Pathway

(2018) Muaz Belviranlı et al.   NEUROMOLECULAR MEDICINE

A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review

(2018) Hassan Askari et al.   PHARMACOLOGICAL RESEARCH

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

Small interfering RNA mediated knockdown of irisin suppresses food intake and modulates appetite regulatory peptides in zebrafish

(2017) Lakshminarasimhan Sundarrajan et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Physiology and role of irisin in glucose homeostasis

(2017) Nikolaos Perakakis et al.   Nature Reviews Endocrinology

The effects of intracerebroventricular infusion of irisin on feeding behaviour in rats

(2017) Suat Tekin et al.   NEUROSCIENCE LETTERS

Irisin in goldfish ( Carassius auratus ): Effects of irisin injections on feeding behavior and expression of appetite regulators, uncoupling proteins and lipoprotein lipase, and fasting-induced changes in FNDC5 expression

(2017) Zahndra Diann Butt et al.   PEPTIDES

Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells

(2017) Shiwei Liu et al.   PLoS One

Effects of Irisin and Exercise on Metabolic Parameters and Reproductive Hormone Levels in High-Fat Diet-Induced Obese Female Mice

(2017) Ercan Bastu et al.   Reproductive Sciences

Effects of Neuropeptide Y on Stem Cells and Their Potential Applications in Disease Therapy

(2017) Song Peng et al.   Stem Cells International

Molecular Therapy of Melanocortin-4-Receptor Obesity by an Autoregulatory BDNF Vector

(2017) Jason J. Siu et al.   Molecular Therapy-Methods & Clinical Development

Crosstalk between adipokines and myokines in fat browning

(2016) A. Rodríguez et al.   Acta Physiologica

Central inhibitory effects on feeding induced by the adipo-myokine irisin

(2016) Claudio Ferrante et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-diabetic activity of recombinant irisin in STZ-induced insulin-deficient diabetic mice

(2016) Huikun Duan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Irisin Increased the Number and Improved the Function of Endothelial Progenitor Cells in Diabetes Mellitus Mice

(2016) Guangxu Zhu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Effects of central irisin administration on the uncoupling proteins in rat brain

(2016) Yavuz Erden et al.   NEUROSCIENCE LETTERS

Irisin protects against endothelial injury and ameliorates atherosclerosis in apolipoprotein E-Null diabetic mice

(2015) Junyan Lu et al.   ATHEROSCLEROSIS

FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity

(2015) Xiao-Qing Xiong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses

(2015) Di Zhu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The 148 M allele of the PNPLA3 is associated with plasma irisin levels in a population sample of Caucasian children: The PANIC Study

(2015) Anna Viitasalo et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Irisin levels before and after physical activity among school-age children with different BMI: A direct relation with leptin

(2015) Berenice Palacios-González et al.   Obesity

The identification of irisin in human cerebrospinal fluid: influence of adiposity, metabolic markers, and gestational diabetes

(2014) Milan K. Piya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

(2013) Christiane D. Wrann et al.   Cell Metabolism

The hypothalamus and metabolism: integrating signals to control energy and glucose homeostasis

(2013) Anthony P Coll et al.   CURRENT OPINION IN PHARMACOLOGY

Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

(2013) Y. Zhang et al.   DIABETES

Association between circulating irisin levels and the promotion of insulin resistance during the weight maintenance period after a dietary weight-lowering program in obese patients

(2013) Ana B. Crujeiras et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity – Correlation with body mass index

(2012) Andreas Stengel et al.   PEPTIDES

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

(2008) Zane B. Andrews et al.   NATURE