Opportunities to debottleneck the downstream processing of the oncolytic measles virus

Forced Degradation Studies to Identify Critical Process Parameters for the Purification of Infectious Measles Virus

(2019) Loewe et al.   Viruses-Basel

High titer oncolytic measles virus production process by integration of dielectric spectroscopy as online monitoring system

(2018) Tanja A. Grein et al.   BIOTECHNOLOGY AND BIOENGINEERING

A generalized purification step for viral particles using mannitol flocculation

(2018) Caryn L. Heldt et al.   BIOTECHNOLOGY PROGRESS

A fast and efficient purification platform for cell-based influenza viruses by flow-through chromatography

(2018) Yu-Fen Tseng et al.   VACCINE

Potential and clinical translation of oncolytic measles viruses

(2017) Steven Robinson et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Effect of mass overloading on binding and elution of unstable proteins in hydrophobic interaction chromatography

(2017) Renata Muca et al.   JOURNAL OF CHROMATOGRAPHY A

Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol

(2017) Pavel Marichal-Gallardo et al.   JOURNAL OF CHROMATOGRAPHY A

Recovery of infective virus particles in ion-exchange and hydrophobic interaction monolith chromatography is influenced by particle charge and total-to-infective particle ratio

(2017) Dora Sviben et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015

(2017) et al.   JAMA Oncology

Stability, biophysical properties and effect of ultracentrifugation and diafiltration on measles virus and mumps virus

(2016) Dora Sviben et al.   ARCHIVES OF VIROLOGY

Clarification of vaccines: An overview of filter based technology trends and best practices

(2016) Lise Besnard et al.   BIOTECHNOLOGY ADVANCES

Oncolytic viruses: finally delivering

(2016) Leonard W Seymour et al.   BRITISH JOURNAL OF CANCER

Nonspecific native elution of proteins and mumps virus in immunoaffinity chromatography

(2016) Marija Brgles et al.   JOURNAL OF CHROMATOGRAPHY A

Mono- and polyprotic buffer systems in anion exchange chromatography of influenza virus particles

(2016) Judith Vajda et al.   JOURNAL OF CHROMATOGRAPHY A

Core bead chromatography for preparation of highly pure, infectious respiratory syncytial virus in the negative purification mode

(2016) Sophia T. Mundle et al.   VACCINE

Measles to the Rescue: A Review of Oncolytic Measles Virus

(2016) Sarah Aref et al.   Viruses-Basel

Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

(2016) Guy Ungerechts et al.   Molecular Therapy-Methods & Clinical Development

Oncolytic Viruses: Therapeutics With an Identity Crisis

(2016) Caroline J. Breitbach et al.   EBioMedicine

Improved virus purification processes for vaccines and gene therapy

(2015) Piergiuseppe Nestola et al.   BIOTECHNOLOGY AND BIOENGINEERING

Regulation of biologic oncology products in the FDA׳s Center for Biologics Evaluation and Research

(2015) Peter F. Bross et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Preparation of pure, high titer, pseudoinfectious Flavivirus particles by hollow fiber tangential flow filtration and anion exchange chromatography

(2015) Sophia T. Mundle et al.   VACCINE

Downstream processing and chromatography based analytical methods for production of vaccines, gene therapy vectors, and bacteriophages

(2015) Petra Kramberger et al.   Human Vaccines & Immunotherapeutics

Oncolytic viruses: From bench to bedside with a focus on safety

(2015) Pascal RA Buijs et al.   Human Vaccines & Immunotherapeutics

Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

(2014) E. Galanis et al.   CANCER RESEARCH

Optimised concentration and purification of retroviruses using membrane chromatography

(2014) D.J. McNally et al.   JOURNAL OF CHROMATOGRAPHY A

A flow-through chromatography process for influenza A and B virus purification

(2014) Thomas Weigel et al.   JOURNAL OF VIROLOGICAL METHODS

Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy

(2014) Stephen J. Russell et al.   MAYO CLINIC PROCEEDINGS

Purification of Vero cell derived live replication deficient influenza A and B virus by ion exchange monolith chromatography

(2014) Marko Banjac et al.   VACCINE

Recent advances in bioprocessing application of membrane chromatography

(2013) Valerie Orr et al.   BIOTECHNOLOGY ADVANCES

Membrane Supported Virus Separation from Biological Solutions

(2013) Tanja A. Grein et al.   CHEMIE INGENIEUR TECHNIK

Purification of infective baculoviruses by monoliths

(2013) Petra Gerster et al.   JOURNAL OF CHROMATOGRAPHY A

Use of hollow fiber tangential flow filtration for the recovery and concentration of HIV virus-like particles produced in insect cells

(2013) Alejandro Negrete et al.   JOURNAL OF VIROLOGICAL METHODS

Next Generation Inactivated Polio Vaccine Manufacturing to Support Post Polio-Eradication Biosafety Goals

(2013) Yvonne E. Thomassen et al.   PLoS One

Attenuated Oncolytic Measles Virus Strains as Cancer Therapeutics

(2012) P. Msaouel et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Principles and applications of steric exclusion chromatography

(2012) Jeremy Lee et al.   JOURNAL OF CHROMATOGRAPHY A

Purification of a recombinant baculovirus of Autographa californica M nucleopolyhedrovirus by ion exchange membrane chromatography

(2012) Tanja A. Grein et al.   JOURNAL OF VIROLOGICAL METHODS

Nectin 4 is the epithelial cell receptor for measles virus

(2012) Ryan S. Noyce et al.   TRENDS IN MICROBIOLOGY

Downstream Processing of Lentiviral Vectors: Releasing Bottlenecks

(2012) Vanessa Bandeira et al.   Human Gene Therapy Methods

Rational design and optimization of downstream processes of virus particles for biopharmaceutical applications: Current advances

(2011) Tiago Vicente et al.   BIOTECHNOLOGY ADVANCES

Highly efficient concentration of lenti- and retroviral vector preparations by membrane adsorbers and ultrafiltration

(2011) Katrin Zimmermann et al.   BMC BIOTECHNOLOGY

Process optimization of diafiltration with time-dependent water adding for albumin production

(2011) Radoslav Paulen et al.   CHEMICAL ENGINEERING AND PROCESSING

Downstream processing of cell culture-derived virus particles

(2011) Michael W Wolf et al.   Expert Review of Vaccines

Stabilization of measles virus for vaccine formulation

(2011) Julian Kissmann et al.   Human vaccines & immunotherapeutics

Concentration and purification of rubella virus using monolithic chromatographic support

(2011) Dubravko Forcic et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Purification of cell culture-derived modified vaccinia ankara virus by pseudo-affinity membrane adsorbers and hydrophobic interaction chromatography

(2010) Michael W. Wolff et al.   BIOTECHNOLOGY AND BIOENGINEERING

Purification of Minute Virus of Mice using high performance tangential flow filtration

(2009) Miriam I. Hensgen et al.   DESALINATION

Purification of recombinant baculoviruses for gene therapy using membrane processes

(2009) T Vicente et al.   GENE THERAPY

Scalable Purification of Adeno-associated Virus Serotype 1 (AAV1) and AAV8 Vectors, Using Dual Ion-Exchange Adsorptive Membranes

(2009) Takashi Okada et al.   HUMAN GENE THERAPY

Purification of anatid herpesvirus 1 particles by tangential-flow ultrafiltration and sucrose gradient ultracentrifugation

(2009) Yufei Guo et al.   JOURNAL OF VIROLOGICAL METHODS

Advances in Primary Recovery: Centrifugation and Membrane Technology

(2008) D.J. Roush et al.   BIOTECHNOLOGY PROGRESS