Mast Cell Biology at Molecular Level: a Comprehensive Review

A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain

(2019) Dustin P. Green et al.   NEURON

Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch

(2019) James Meixiong et al.   IMMUNITY

Role of Mast Cells in Shaping the Tumor Microenvironment

(2019) Daniel Elieh Ali Komi et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Overexpression of Notch ligand Delta-like-1 by dendritic cells enhances their immunoregulatory capacity and exerts antiallergic effects on Th2-mediated allergic asthma in mice

(2018) Chen-Chen Lee et al.   CLINICAL IMMUNOLOGY

Is it time for a new classification of mast cells? What do we know about mast cell heterogeneity?

(2018) Barbara Frossi et al.   IMMUNOLOGICAL REVIEWS

The role and relevance of mast cells in urticaria

(2018) Martin K. Church et al.   IMMUNOLOGICAL REVIEWS

Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells

(2018) Jeremy A. O'Sullivan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers

(2017) Mohamed H. Shamji et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Globule Leukocytes and Other Mast Cells in the Mouse Intestine

(2017) Peter Vogel et al.   VETERINARY PATHOLOGY

Interactions between Innate Lymphoid Cells and Cells of the Innate and Adaptive Immune System

(2017) Cornelia Symowski et al.   Frontiers in Immunology

Mast cell differentiation: still open questions?

(2016) M. Arock   BLOOD

Of Mouse Models of Mast Cell Deficiency and Metabolic Syndrome

(2016) Thorsten B. Feyerabend et al.   Cell Metabolism

Role of Mast Cells in the Pathogenesis of Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

(2016) Daniel Elieh-Ali-Komi et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Airway inflammation in asthma

(2016) Alex KleinJan   CURRENT OPINION IN PULMONARY MEDICINE

Mast Cells Regulate Wound Healing in Diabetes

(2016) Ana Tellechea et al.   DIABETES

Molecular mechanisms of regulation of Toll-like receptor signaling

(2016) Cynthia A. Leifer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Emerging concepts: mast cell involvement in allergic diseases

(2016) Brian D. Modena et al.   Translational Research

Important role of mast cells in multiple sclerosis

(2016) P. Conti et al.   Multiple Sclerosis and Related Disorders

No Role for Mast Cells in Obesity-Related Metabolic Dysregulation

(2016) Jindřich Chmelař et al.   Frontiers in Immunology

Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

(2016) Dean D. Metcalfe et al.   World Allergy Organization Journal

Lin- CD34hi CD117int/hi Fc RI+ cells in human blood constitute a rare population of mast cell progenitors

(2015) J. S. Dahlin et al.   BLOOD

From IgE to clinical trials of allergic rhinitis

(2015) Giorgio Ciprandi et al.   Expert Review of Clinical Immunology

Mast cells and dendritic cells form synapses that facilitate antigen transfer for T cell activation

(2015) Amanda Carroll-Portillo et al.   JOURNAL OF CELL BIOLOGY

Mast Cell and Autoimmune Diseases

(2015) Yunzhi Xu et al.   MEDIATORS OF INFLAMMATION

Mast cell mediator responses and their suppression by pathogenic and commensal microorganisms

(2015) Hae Woong Choi et al.   MOLECULAR IMMUNOLOGY

Potential effector and immunoregulatory functions of mast cells in mucosal immunity

(2015) L L Reber et al.   Mucosal Immunology

Distinguishing Mast Cell Progenitors from Mature Mast Cells in Mice

(2015) Joakim S. Dahlin et al.   STEM CELLS AND DEVELOPMENT

Mast Cells as Regulators of T Cell Responses

(2015) Silvia Bulfone-Paus et al.   Frontiers in Immunology

Mast cell/MDSC a liaison immunosuppressive for tumor microenvironment

(2015) Luca Danelli et al.   OncoImmunology

Mast Cells Protect against Pseudomonas aeruginosa–Induced Lung Injury

(2014) Robert D. Junkins et al.   AMERICAN JOURNAL OF PATHOLOGY

Characterization of Mast Cell Secretory Granules and Their Cell Biology

(2014) Nurit Pereg Azouz et al.   DNA AND CELL BIOLOGY

Siglec-7 is an inhibitory receptor on human mast cells and basophils

(2014) Sa'ar Mizrahi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis

(2014) Albert Dahdah et al.   JOURNAL OF CLINICAL INVESTIGATION

Mast Cell IL-6 Improves Survival from Klebsiella Pneumonia and Sepsis by Enhancing Neutrophil Killing

(2014) R. E. Sutherland et al.   JOURNAL OF IMMUNOLOGY

Mast cell histamine promotes the immunoregulatory activity of myeloid-derived suppressor cells

(2014) Rebecca K. Martin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

(2014) Benjamin D. McNeil et al.   NATURE

Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells

(2014) E. Lefrancais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are mast cells instrumental for fibrotic diseases?

(2014) Catherine Overed-Sayer et al.   Frontiers in Pharmacology

Vesicular Trafficking and Signaling for Cytokine and Chemokine Secretion in Mast Cells

(2014) Ulrich Blank et al.   Frontiers in Immunology

Mast Cell Mediators: Their Differential Release and the Secretory Pathways Involved

(2014) Tae Chul Moon et al.   Frontiers in Immunology

Mast cells and basophils are essential for allergies: mechanisms of allergic inflammation and a proposed procedure for diagnosis

(2013) Shao-heng He et al.   ACTA PHARMACOLOGICA SINICA

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Mast cells: from lipid droplets to lipid mediators

(2013) Andrea Dichlberger et al.   CLINICAL SCIENCE

Mast cell activity in the healing wound: more than meets the eye?

(2013) Brian C. Wulff et al.   EXPERIMENTAL DERMATOLOGY

Mechanisms of Granule Membrane Recapture following Exocytosis in Intact Mast Cells

(2013) Jose M. Cabeza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate Immunity and Its Regulation by Mast Cells

(2013) A. L. St. John et al.   JOURNAL OF IMMUNOLOGY

Mast Cells Play a Key Role in Host Defense against Herpes Simplex Virus Infection through TNF-α and IL-6 Production

(2013) Rui Aoki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Rat Embryonic Mast Cells Originate in the AGM

(2013) Michel Farchi Guiraldelli et al.   PLoS One

Insights into mast cell functions in asthma using mouse models

(2013) Ying Lei et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Role of Interleukin-33 in Innate-Type Immune Cells in Allergy

(2013) Susumu Nakae et al.   ALLERGOLOGY INTERNATIONAL

Mast Cell Activation Syndrome: A Review

(2012) Marianne Frieri et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Mast Cell Proteoglycans

(2012) Elin Rönnberg et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

IgE and mast cells in allergic disease

(2012) Stephen J Galli et al.   NATURE MEDICINE

Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions

(2012) Takumi Kiwamoto et al.   PHARMACOLOGY & THERAPEUTICS

New models for analyzing mast cell functions in vivo

(2012) Laurent L. Reber et al.   TRENDS IN IMMUNOLOGY

Cytoskeleton in Mast Cell Signaling

(2012) Pavel Dráber et al.   Frontiers in Immunology

Novel Identified Receptors on Mast Cells

(2012) Helena Migalovich-Sheikhet et al.   Frontiers in Immunology

T Cell-Mediated Modulation of Mast Cell Function: Heterotypic Adhesion-Induced Stimulatory or Inhibitory Effects

(2012) Yoseph A. Mekori et al.   Frontiers in Immunology

Role and Relevance of Mast Cells in Fungal Infections

(2012) R. Saluja et al.   Frontiers in Immunology

Mast Cell: An Emerging Partner in Immune Interaction

(2012) Giorgia Gri et al.   Frontiers in Immunology

Mast Cells are Important Modifiers of Autoimmune Disease: With so Much Evidence, Why is There Still Controversy?

(2012) Melissa A. Brown et al.   Frontiers in Immunology

Mast Cell Chemotaxis – Chemoattractants and Signaling Pathways

(2012) Ivana Halova et al.   Frontiers in Immunology

The SNARE Machinery in Mast Cell Secretion

(2012) Axel Lorentz et al.   Frontiers in Immunology

New insights into the role of mast cells in autoimmunity: Evidence for a common mechanism of action?

(2011) Margaret E. Walker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice

(2011) J. N. Lilla et al.   BLOOD

Plasticity in mast cell responses during bacterial infections

(2011) Cheryl Y Chan et al.   CURRENT OPINION IN MICROBIOLOGY

Mast Cells in Tissue Healing: From Skin to the Gastrointestinal Tract

(2011) Rory Kennelly et al.   CURRENT PHARMACEUTICAL DESIGN

Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of Haptens

(2011) Anne Dudeck et al.   IMMUNITY

Cre-Mediated Cell Ablation Contests Mast Cell Contribution in Models of Antibody- and T Cell-Mediated Autoimmunity

(2011) Thorsten B. Feyerabend et al.   IMMUNITY

SNARE complex-mediated degranulation in mast cells

(2011) Joseph R. Woska et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Processing of Human Protryptase in Mast Cells Involves Cathepsins L, B, and C

(2011) Q. T. Le et al.   JOURNAL OF IMMUNOLOGY

Kit (W-sh) Mice Develop Earlier and More Severe Experimental Autoimmune Encephalomyelitis Due to Absence of Immune Suppression

(2011) H. Li et al.   JOURNAL OF IMMUNOLOGY

Skin Mast Cells Protect Mice against Vaccinia Virus by Triggering Mast Cell Receptor S1PR2 and Releasing Antimicrobial Peptides

(2011) Z. Wang et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Enhance Mast Cell Production of IL-6 via Surface-Bound TGF- 

(2011) K. Ganeshan et al.   JOURNAL OF IMMUNOLOGY

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

Requirement of Interaction between Mast Cells and Skin Dendritic Cells to Establish Contact Hypersensitivity

(2011) Atsushi Otsuka et al.   PLoS One

Mast cells and inflammation

(2010) Theoharis C. Theoharides et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mast cell repopulation of the peritoneal cavity: contribution of mast cell progenitors versus bone marrow derived committed mast cell precursors

(2010) Maria Jamur et al.   BMC IMMUNOLOGY

Mast cell mediators in tolerance

(2010) Victor C de Vries et al.   CURRENT OPINION IN IMMUNOLOGY

Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity

(2010) Stephen J. Galli et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mast cell signaling: The role of protein tyrosine kinase Syk, its activation and screening methods for new pathway participants

(2010) Reuben P. Siraganian et al.   FEBS LETTERS

IgE, mast cells, basophils, and eosinophils

(2010) Kelly D. Stone et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulation of secretory granule size by the precise generation and fusion of unit granules

(2010) Ilan Hammel et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Polyamines Are Present in Mast Cell Secretory Granules and Are Important for Granule Homeostasis

(2010) Gianni García-Faroldi et al.   PLoS One

The role of mast cells in wound healing

(2010) Michael FY Ng   International Wound Journal

Mast Cell Peptidases

(2009) Neil N. Trivedi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mast Cell Degranulation Breaks Peripheral Tolerance

(2009) V. C. de Vries et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Human Mast Cells Stimulate Activated T Cells

(2009) Theoharis C. Theoharides et al.   Annals of the New York Academy of Sciences

Mast Cells

(2009) Kavitha N. Rao et al.   Annals of the New York Academy of Sciences

T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis

(2009) Elias Gounaris et al.   CANCER RESEARCH

Our perception of the mast cell from Paul Ehrlich to now

(2009) Michael A. Beaven   EUROPEAN JOURNAL OF IMMUNOLOGY

The tyrosine kinase network regulating mast cell activation

(2009) Alasdair M. Gilfillan et al.   IMMUNOLOGICAL REVIEWS

Adapters in the organization of mast cell signaling

(2009) Damiana Alvarez-Errico et al.   IMMUNOLOGICAL REVIEWS

Mast cell and T cell communication; amplification and control of adaptive immunity

(2009) Alon Y. Hershko et al.   IMMUNOLOGY LETTERS

Pathophysiological Role of Skin Mast Cells in Wound Healing after Scald Injury: Study with Mast Cell-Deficient W/WV Mice

(2009) Naotaka Shiota et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

TLR2-dependent mast cell activation contributes to the control of Mycobacterium tuberculosis infection

(2009) Daniela Carlos et al.   MICROBES AND INFECTION

P2 receptor-mediated signaling in mast cell biology

(2009) Elena Bulanova et al.   Purinergic Signalling

Mast Cell Regulation of the Immune Response

(2009) John J. Ryan et al.   World Allergy Organization Journal

SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

(2008) B. Huang et al.   BLOOD

Acute exposure of human skin to ultraviolet or infrared radiation or heat stimuli increases mast cell numbers and tryptase expression in human skinin vivo

(2008) M-S. Kim et al.   BRITISH JOURNAL OF DERMATOLOGY

Mast cells as regulators of adaptive immunity to tumours

(2008) A. Wasiuk et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mast cell activation by myelin through scavenger receptor

(2008) Nevenka Medic et al.   JOURNAL OF NEUROIMMUNOLOGY

New developments in mast cell biology

(2008) Janet Kalesnikoff et al.   NATURE IMMUNOLOGY

Urochordate Histoincompatible Interactions Activate Vertebrate-Like Coagulation System Components

(2008) Matan Oren et al.   PLoS One

Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms

(2008) N. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA