A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes

Role of activating transcription factor 3 in fructose-induced metabolic syndrome in mice

(2018) Chu-Lin Chou et al.   HYPERTENSION RESEARCH

A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver

(2018) Tobias Strunz et al.   Scientific Reports

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

(2018) Derek Klarin et al.   NATURE GENETICS

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

(2016) Kaixin Zhou et al.   NATURE GENETICS

Genomic Characterization of Metformin Hepatic Response

(2016) Marcelo R. Luizon et al.   PLoS Genetics

Role of Nrf2 in the pathogenesis of atherosclerosis

(2015) Junsei Mimura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gender-related lipid and/or lipoprotein responses to statins in subjects in primary and secondary prevention

(2015) Giuliana Mombelli et al.   Journal of Clinical Lipidology

From genome to function by studying eQTLs

(2014) Harm-Jan Westra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants atDPYDand a putative role forENOSF1rather thanTYMS

(2014) Dan Rosmarin et al.   GUT

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

Heritability and genomics of gene expression in peripheral blood

(2014) Fred A Wright et al.   NATURE GENETICS

Genomic architecture of pharmacological efficacy and adverse events

(2014) Aparna Chhibber et al.   PHARMACOGENOMICS

Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

Foxa1 and Foxa2 Are Essential for Sexual Dimorphism in Liver Cancer

(2012) Zhaoyu Li et al.   CELL

Genome-Wide Association Study Evaluating Lipoprotein-Associated Phospholipase A 2 Mass and Activity at Baseline and After Rosuvastatin Therapy

(2012) Audrey Y. Chu et al.   Circulation-Cardiovascular Genetics

Sex-biased genetic effects on gene regulation in humans

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Liver expression quantitative trait loci: a foundation for pharmacogenomic research

(2012) Dylan M. Glubb et al.   Frontiers in Genetics

Endogenous Estrogens Lower Plasma PCSK9 and LDL Cholesterol But Not Lp(a) or Bile Acid Synthesis in Women

(2011) Lena Persson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The PPAR-RXR Transcriptional Complex in the Vasculature

(2011) Jorge Plutzky   CIRCULATION RESEARCH

A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort

(2011) D. M. Greenawalt et al.   GENOME RESEARCH

Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver

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Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease

(2011) Yijing Zhang et al.   PLoS One

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

(2011) Federico Innocenti et al.   PLoS Genetics

Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters

(2010) Dylan M. Glubb et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies

(2010) Oliver Stegle et al.   PLoS Computational Biology

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Genetic and Metabolic Determinants of Plasma PCSK9 Levels

(2009) Susan G. Lakoski et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Activating Transcription Factor 3 Is a Novel Repressor of the Nuclear Factor Erythroid-Derived 2 Related Factor 2 (Nrf2) Regulated Stress Pathway

(2008) S. L. Brown et al.   CANCER RESEARCH

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY