A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes
出版年份 2019 全文链接
标题
A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes
作者
关键词
-
出版物
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-12-23
DOI
10.1002/cpt.1751
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Role of activating transcription factor 3 in fructose-induced metabolic syndrome in mice
- (2018) Chu-Lin Chou et al. HYPERTENSION RESEARCH
- A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver
- (2018) Tobias Strunz et al. Scientific Reports
- Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program
- (2018) Derek Klarin et al. NATURE GENETICS
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
- (2016) Kaixin Zhou et al. NATURE GENETICS
- Genomic Characterization of Metformin Hepatic Response
- (2016) Marcelo R. Luizon et al. PLoS Genetics
- Role of Nrf2 in the pathogenesis of atherosclerosis
- (2015) Junsei Mimura et al. FREE RADICAL BIOLOGY AND MEDICINE
- Gender-related lipid and/or lipoprotein responses to statins in subjects in primary and secondary prevention
- (2015) Giuliana Mombelli et al. Journal of Clinical Lipidology
- From genome to function by studying eQTLs
- (2014) Harm-Jan Westra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants atDPYDand a putative role forENOSF1rather thanTYMS
- (2014) Dan Rosmarin et al. GUT
- An atlas of genetic influences on human blood metabolites
- (2014) So-Youn Shin et al. NATURE GENETICS
- Heritability and genomics of gene expression in peripheral blood
- (2014) Fred A Wright et al. NATURE GENETICS
- Genomic architecture of pharmacological efficacy and adverse events
- (2014) Aparna Chhibber et al. PHARMACOGENOMICS
- Matrix eQTL: ultra fast eQTL analysis via large matrix operations
- (2012) A. A. Shabalin BIOINFORMATICS
- Foxa1 and Foxa2 Are Essential for Sexual Dimorphism in Liver Cancer
- (2012) Zhaoyu Li et al. CELL
- Genome-Wide Association Study Evaluating Lipoprotein-Associated Phospholipase A 2 Mass and Activity at Baseline and After Rosuvastatin Therapy
- (2012) Audrey Y. Chu et al. Circulation-Cardiovascular Genetics
- Sex-biased genetic effects on gene regulation in humans
- (2012) A. S. Dimas et al. GENOME RESEARCH
- Liver expression quantitative trait loci: a foundation for pharmacogenomic research
- (2012) Dylan M. Glubb et al. Frontiers in Genetics
- Endogenous Estrogens Lower Plasma PCSK9 and LDL Cholesterol But Not Lp(a) or Bile Acid Synthesis in Women
- (2011) Lena Persson et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The PPAR-RXR Transcriptional Complex in the Vasculature
- (2011) Jorge Plutzky CIRCULATION RESEARCH
- A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
- (2011) D. M. Greenawalt et al. GENOME RESEARCH
- Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver
- (2011) A Schröder et al. PHARMACOGENOMICS JOURNAL
- Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease
- (2011) Yijing Zhang et al. PLoS One
- Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue
- (2011) Federico Innocenti et al. PLoS Genetics
- Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters
- (2010) Dylan M. Glubb et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies
- (2010) Oliver Stegle et al. PLoS Computational Biology
- Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
- (2010) Dan L. Nicolae et al. PLoS Genetics
- Genetic and Metabolic Determinants of Plasma PCSK9 Levels
- (2009) Susan G. Lakoski et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Activating Transcription Factor 3 Is a Novel Repressor of the Nuclear Factor Erythroid-Derived 2 Related Factor 2 (Nrf2) Regulated Stress Pathway
- (2008) S. L. Brown et al. CANCER RESEARCH
- Mapping the Genetic Architecture of Gene Expression in Human Liver
- (2008) Eric E Schadt et al. PLOS BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started